The effects of alcohol on laboratory-measured impulsivity after L-Tryptophan depletion or loading

Psychopharmacology

Volumn 193, Issue 1, 2007, Pages 137-150

  Dougherty, Donald M ^a   Marsh, Dawn M ^a   Mathias, Charles W ^a   Dawes, Michael A ^a   Bradley, Don M ^b   Morgan, Chris J ^c   Badawy, Abdulla A B ^d  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^d CARDIFF METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Alcohol; Humans; Impulsivity; L tryptophan depletion; Serotonin

Indexed keywords

ALCOHOL; SEROTONIN; TRYPTOPHAN;

ADULT; ARTICLE; BIOSYNTHESIS; BREATH ANALYSIS; CHEMICALLY INDUCED DISORDER; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; IMPULSIVENESS; MALE; METABOLISM; NEUROPSYCHOLOGICAL TEST; PSYCHOLOGICAL ASPECT;

ADULT; BREATH TESTS; DOUBLE-BLIND METHOD; ETHANOL; FEMALE; HUMANS; IMPULSIVE BEHAVIOR; MALE; NEUROPSYCHOLOGICAL TESTS; SEROTONIN; TRYPTOPHAN;

EID: 34548463098     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-007-0763-6     Document Type: Article

References (126)

1. Allen TJ, Moeller FG, Rhoades HR, Cherek DR (1998) Impulsivity and history of drug dependence. Drug Alcohol Depend 50:137-145 (Pubitemid 28271628)
2. Asberg M, Traskman L, Thoren P (1976) 5-HIAA in the cerebrospinal fluid: a biochemical suicide predictor. Arch Gen Psychiatry 33:1193-1197
3. Asberg M, Nordstrom P, Traskman-Bendz L (1986) Cerebrospinal fluid studies in suicide: an overview. Ann N Y Acad Sci 487:243-255
4. Badawy AA-B (1998) Alcohol, aggression and serotonin: metabolic aspects. Alcohol Alcohol 33:66-72
5. Badawy AA-B (2003) Alcohol and violence and the possible role of serotonin. Crim Behav Ment Health 13:31-44
6. Badawy AA, Morgan CJ, Lovett JW, Bradley DM, Thomas R (1995) Decrease in circulating tryptophan availability to the brain after acute ethanol consumption by normal volunteers: implications for alcohol-induced aggressive behaviour and depression. Pharmacopsychiatry 28:93-97
7. Badawy AA-B, Morgan CJ, Llewelyn MB, Albuquerque, SRJ, Farmer A (2005) Heterogeneity of serum tryptophan concentration and availability to the brain in patients with the chronic fatigue syndrome. J Psychopharmacol 19:385-391 (Pubitemid 41003134)
8. Ballenger JC, Goodwin FK, Major LF, Brown GL (1979) Alcohol and central serotonin metabolism in man. Arch Gen Psychiatry 36:224-227 (Pubitemid 9098809)
9. Banki CM (1981) Factors influencing monoamine metabolites and tryptophan in patients with alcohol dependence. J Neural Transm 50:89-101
10. Banki CM, Arato M (1983) Amine metabolites, neuroendocrine findings, and personality dimensions as correlates of suicidal behavior. Psychiatry Res 10:253-261 (Pubitemid 14223179)
11. Barkley RA (1991) The ecological validity of laboratory and analogue assessment methods of ADHD symptoms. J Abnorm Child Psychol 19:149-178
12. Barratt ES, Patton JH (1983) Impulsivity: cognitive, behavioral and psychophysiological correlates. In: Zuckerman M (ed) Biological bases of sensation seeking, impulsivity, and anxiety. Lawrence Earlbaum Associates, Hillsdale, NJ, pp 77-121
13. Beale IL, Matthew PJ, Oliver S, Cornballis MC (1987) Performance of disabled and normal readers on the Continuous Performance Test. J Abnorm Child Psychol 15:229-238
14. Benkelfat C, Ellenbogen MA, Dean P, Palmour RM, Young SN (1994) Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders. Arch Gen Psychiatry 51:687-697
15. Berney A, Sookman D, Leyton M, Young SN, Benkelfat C (2006) Lack of effects on core obsessive-compulsive symptoms of tryptophan depletion during symptom provocation in remitted obsessive-compulsive disorder patients. Biol Psychiatry 59:853-857
16. Bhatti T, Gillin JC, Seifritz E, Moore P, Clark C, Golshan S, Stahl S, Rapaport M, Kelsoe J (1998) Effects of a tryptophan-free amino acid drink challenge on normal human sleep electroencephalogram and mood. Biol Psychiatry 43:52-59 (Pubitemid 28059072)
17. Biggio G, Fadda F, Fanni P, Tagliamonte A, Gessa GL (1974) Rapid depletion of serum tryptophan, brain tryptophan, serotonin and 5-hydroxyindoleacetic acid by a tryptophan-free diet. Life Sci 14:1321-1329
18. Bjork JM, Dougherty DM, Moeller FG, Cherek DR, Swann AC (1999) The effects of tryptophan depletion and loading on laboratory aggression in men: time course and a food-restricted control. Psychopharmacology 142:24-30 (Pubitemid 29196060)
19. Bjork JM, Dougherty DM, Moeller FG, Swann AC (2000) Differential behavioral effects of plasma tryptophan depletion and loading in aggressive and nonaggressive men. Neuropsychopharmacology 22:357-369 (Pubitemid 30105764)
20. Booij L, van der Does AJ, Riedel WJ (2003) Monoamine depletion in psychiatric and healthy populations: review. Mol Psychiatry 88:951-973 (Pubitemid 37523908)
21. Booij L, van der Does AJ, Haffmans PM, Riedel WJ (2005) Acute tryptophan depletion as a model of depressive relapse: behavioural specificity and ethical considerations. J Affect Disord 86:305-311
22. Borg S, Kvande H, Liljeberg P, Mossberg D, Valverius P (1985) 5-Hydroxyindoleacetic acid in cerebrospinal fluid in alcoholic patients under different clinical conditions. Alcohol 2:415-418 (Pubitemid 15242723)
23. Brown GL, Ballanger JC, Minichiello MD, Goodwin FK (1979) Human aggression and its relationship to cerebrospinal fluid 5-hydroxyindoleacetic acid, 3-methoxy-4-hydroxyphenylglycol, and homovanillic acid. In: Sandler M (ed) Psychopharmacology of aggression. Raven, New York, pp 131-148
24. Brown GL, Ebert MH, Goyer PF, Jimerson DC, Klein WJ, Bunney WE, Goodwin FK (1982) Aggression, suicide, and serotonin: relationships to CSF amine metabolites. Am J Psychiatry 139:741-746 (Pubitemid 12123213)
25. Buss AH, Perry M (1992) The Aggression Questionnaire. J Pers Soc Psychol 63:452-459
26. Cappiello A, Sernyak MJ, Malison RT, McDougle CJ, Heninger GR, Price LH (1997) Effects of acute tryptophan depletion in lithium-remitted manic patients: a pilot study. Biol Psychiatry 42:1076-1078 (Pubitemid 27496440)
27. Carlsson A, Lindqvist M (1978) Dependence of 5-HT and catecholamine synthesis on concentrations of precursor amino acids in rat brain. Naunyn Schmiedebergs Arch Pharmacol 303:157-164 (Pubitemid 8369123)
28. Carpenter LL, Anderson GA, Pelton GH, Gudin JA, Kirwin PDS, Price LH, Heninger GR, McDougal CJ (1998) Tryptophan depletion during continuous CSF sampling in healthy human subjects. Neuropsychopharmacology 19:26-35 (Pubitemid 28255211)
29. Carver CS, Miller CJ (2006) Relations of serotonin function to personality: current views and a key methodological issue. Psychiatry Res 144:1-15 (Pubitemid 44332540)
30. Chambers RA, Taylor JR, Potenza MN (2003) Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. Am J Psychiatry 160:1041-1052 (Pubitemid 41070962)
31. Cherek DR, Moeller FG, Schnapp W, Dougherty DM (1997) Studies of violent and nonviolent male parolees: I. Laboratory and psychometric measurements of aggression. Biol Psychiatry 41:514-522 (Pubitemid 27145537)
32. Cleare AJ, Bond AJ (1995) The effect of tryptophan depletion and enhancement on subjective and behavioral aggression in normal healthy male subjects. Psychopharmacology 118:72-81
33. Coccaro EF, Berman ME, Kavoussi RJ (1997) Assessment of life history of aggression: development and psychometric characteristics. Psychiatry Res 73:147-157 (Pubitemid 28088171)
34. Cornblatt BA, Risch NJ, Faris G, Friedman D, Erlenmeyer-Kimling L (1988) The Continuous Performance Test: Identical Pairs Version (CPT-IP) I. New findings about sustained attention in normal families. Psychiatry Res 26:223-238
35. Crean J, Richards JB, deWit H (2002) Effect of tryptophan depletion on impulsive behavior in men with or without a family history of alcoholism. Behav Brain Res 15:349-357 (Pubitemid 35333250)
36. Curzon G (1979) Relationship between plasma, CSF and brain tryptophan. J Neural Transm 15(Suppl):81-92
37. de Wit H, Crean J, Richards JB (2000) Effects of d-amphetamine and ethanol on a measure of behavioral inhibition in humans. Behav Neurosci 114:830-837 (Pubitemid 30646572)
38. Delgado PL, Charney DS, Price LH, Aghajanian GK, Landis H, Heninger GR (1990) Serotonin function and the mechanism of antidepressant action: reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatry 47:411-418 (Pubitemid 20161259)
39. Dougherty DM, Marsh DM (2003) Immediate and Delayed Memory Tasks (IMT/DMT 2.0): a research tool for studying attention, memory, and impulsive behavior (Manual). Neurobehavioral Research Laboratory and Clinic, University of Texas Health Science Center at Houston, Houston, Texas
40. Dougherty DM, Bjork JM, Bennett RH, Moeller FG (1999a) The effects of a cumulative alcohol dosing procedure on laboratory aggression in men and women. J Stud Alcohol 60:322-329 (Pubitemid 29214833)
41. Dougherty DM, Bjork JM, Marsh DM, Moeller FG (1999b) Influence of trait hostility on tryptophan depletion-induced laboratory aggression. Psychiatry Res 88:227-232 (Pubitemid 30074178)
42. Dougherty DM, Moeller FG, Bjork JM, Marsh DM (1999c) Plasma L-tryptophan depletion and aggression. Adv Exp Med Biol 467:57-65 (Pubitemid 32202141)
43. Dougherty DM, Moeller FG, Bjork JM, Marsh DM (1999d) Plasma L-tryptophan depletion and aggression. In: Huether G, Kochen W, Simat TJ, Steinhart H (eds) Tryptophan, serotonin and melatonin: basic aspects and applications. Kluwer Academic/Plenum, New York, pp 57-65
44. Dougherty DM, Moeller FG, Steinberg JL, Marsh DM, Hines SE, Bjork JM (1999e) Alcohol increases commission error rates for a continuous performance test. Alcohol Clin Exp Res 23:1342-1351 (Pubitemid 29409348)
45. Dougherty DM, Marsh DM, Moeller FG, Chokshi RV, Rosen VC (2000) The effects of moderate and high doses of alcohol on attention, impulsivity, discriminability, and response bias in immediate and delayed memory task performance. Alcohol Clin Exp Res 24:1702-1711
46. Dougherty DM, Marsh DM, Mathias CW (2002) Immediate and Delayed Memory Tasks: a computerized measure of memory, attention, and impulsivity. Behav Res Meth Instrum Comput 34:391-398
47. Dougherty DM, Bjork JM, Harper RA, Marsh DM, Moeller FG, Mathias CW (2003a) Behavioral impulsivity paradigms: a comparison in hospitalized adolescents with disruptive behavior disorders. J Child Psychol Psychiatry 44:1145-1157 (Pubitemid 37461056)
48. Dougherty DM, Bjork JM, Harper RA, Mathias CW, Moeller FG, Marsh DM (2003b) Validation of the Immediate and Delayed Memory Tasks in hospitalized adolescents with disruptive behavior disorders. Psychol Rec 53:509-532 (Pubitemid 37496360)
49. Dougherty DM, Marsh DM, Mathias CW, Morgan CJ, Bradley DM, Badawy AA-B (2004) Impulsive behaviour differences following combined alcohol and L-tryptophan depletion/loading manipulation. J Psychopharmacol 18(Suppl to No 3):A32
50. Dougherty DM, Marsh DM, Mathias CW, Swann AC (2005a) Bipolar disorder and substance abuse: the conceptualization and role of impulsivity. Psychiatric Times 22:32-35
51. Dougherty DM, Mathias CW, Marsh DM, Jagar AA (2005b) Laboratory behavioral measures of impulsivity. Behav Res Meth Instrum Comput 37:82-90 (Pubitemid 41560261)
52. Drummond PD (2005) Effect of tryptophan depletion on symptoms of motion sickness in migraineurs. Neurology 65:620-622
53. Dufour MC (1999) What is moderate drinking? Defining "drinks" and drinking levels. Alcohol Res Health 23:5-14
54. Dykman RA, Ackerman PT, Oglesby DM (1979) Selective and sustained attention in hyperactive, learning-disabled and normal boys. J Nerv Ment Dis 167:288-297 (Pubitemid 9188716)
55. Eckardt MJ, File SE, Gessa GL, Grant KA, Guerri C, Hoffman PL, Kalant H, Koob GF, Li TK, Tabakoff B (1998) Effects of moderate alcohol consumption on the central nervous system. Alcohol Clin Exp Res 22:998-1040 (Pubitemid 28408991)
56. Erickson CK, Matchett JA (1975) Correlation of brain amine changes with ethanol-induced sleep time in mice. In: Gross MM (ed) Alcohol intoxication and withdrawal. Experimental studies II. Plenum, New York, pp 419-430
57. Evenden JL (1999) Varieties of impulsivity. Psychopharmacology 146:348-361
58. Feola TW, de Wit H, Richards JB (2000) Effects of d-amphetamine and alcohol on a measure of behavioral inhibition in rats. Behav Neurosci 114:838-848 (Pubitemid 30646573)
59. Fernstrom JD (1983) Role of precursor availability in control of monoamine biosynthesis in brain. Physiol Rev 63:484-546
60. Fernstrom JD, Wurtman RJ (1972) Brain serotonin content: physiological regulation by plasma neutral amino acids. Science 178:414-416
61. First MB, Gibbon M, Spitzer RL, Williams JBW, Benjamin L (1997) Structured clinical interview for DSM-IV Axis II Personality Disorders (SCID-II). Biometrics Research, New York State Psychiatric Institute, NY
62. First MB, Spitzer RL, Gibbon M, Williams JBW (2001) Structured clinical interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition (SCID-I/NP). Biometrics Research, New York State Psychiatric Institute, NY
63. Gessa GL, Biggio G, Fadda F, Corsini GU, Tagliamonte A (1974) Effect of the oral administration of tryptophan-free amino acid mixtures on serum tryptophan, brain tryptophan and serotonin metabolism. J Neurochem 22:869-870
64. Giancola PR (2002) Irritability, acute alcohol consumption and aggressive behavior in men and women. Drug Alcohol Depend 68:263-274
65. Guimarães APM, Zeni C, Polanczyk GV, Genro JP, Roman T, Rohde LA, Hutz MH (2006) Serotonin genes and attention deficit/hyperactivity disorder in a brazilian sample: preferential transmission of the HTR2A 452His allele to affected boys. Am J Med Genet Part B, Sep 6; [Epub ahead of print]
66. Halperin JM, Wolf LE, Pascualvaca D, Newcorn JH, Healey JM, O'Brien JD, Morganstein A, Young J (1988) Differential assessment of attention and impulsivity in children. J Am Acad Child Adolesc Psych 27:326-329
67. Halperin JM, Wolf LE, Greenblatt ER, Young G (1991) Subtype analysis of commission errors on the continuous performance test. Dev Neuropsychol 7:207-217
68. Higley JD (2001) Individual differences in alcohol-induced aggression: a nonhuman primate model. Alcohol Res Health 25:12-19
69. Hindmarch I, Kerr JS, Sherwood N (1991) The effects of alcohol and other drugs on psychomotor performance and cognitive function. Alcohol 26:71-79
70. Keppel G (1991) Design and analysis: a researcher's handbook. Prentice Hall, Englewood Cliffs, NJ
71. Kruesi MJ (1989) Cruelty to animals and CSF 5-HIAA (letter). Psychiatry Res 28:115-116
72. Kruesi MJ, Rapoport JL, Hamburger S, Hibbs E, Potter WZ, Lenane M, Brown GL (1990) Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescent. Arch Gen Psychiatry 47(5):419-426 (Pubitemid 20161260)
73. Kruesi MJ, Hibbs ED, Zahn TP, Keysor CS, Manburger SD, Bartko JJ, Rapoport JL (1992) A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures? Arch Gen Psychiatry 49(6):429-435
74. LeMarquand DG, Pihl RO, Young SN, Tremblay RE, Seguin JR, Palmour RM, Benkelfat C (1998) Tryptophan depletion, executive functions, and disinhibition in aggressive, adolescent males. Neuropsychopharmacology 19:333-341 (Pubitemid 28491342)
75. LeMarquand DG, Benkelfat C, Pihl RO, Palmour RM, Young SN (1999) Behavioral disinhibition induced by tryptophan depletion in nonalcoholic young men with multigenerational family histories of paternal alcoholism. Am J Psychiatry 156:1771-1779 (Pubitemid 29517571)
76. Li J, Wang Y, Zhou R, Zhang H, Yang L, Wang B, Faraone SV (2007) Association between polymorphisms in serotonin transporter gene and attention deficit hyperactivity disorder in Chinese Han subjects. Am J Med Genet B Neuropsychiatr Genet 144(1):14-19 (Pubitemid 46122633)
77. Lidberg L, Tuck JR, Asberg M, Scalia-Tomba GP, Bertilsson L (1985) Homicide, suicide and CSF 5-HIAA. Acta Psychiatr Scand 71(3):230-236 (Pubitemid 15169898)
78. Limson R, Goldman D, Roy A, Lamparski D, Ravitz B, Adinoff B, Linnoila M (1991) Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. Arch Gen Psychiatry 48:437-441
79. López-Ibor JJ Jr, Saiz-Ruiz J, de los Cobos JCP (1985) Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan. Neuropsychobiology 14:67-74
80. Marsh DM, Dougherty DM, Moeller FG, Swann AC, Spiga R (2002) Laboratory-measured aggressive behavior of women: acute tryptophan depletion and augmentation. Neuropsychopharmacology 26:660-671 (Pubitemid 34260985)
81. Mathias CW, Dougherty DM, Marsh DM, Moeller FG, Hicks LR, Dasher K, Bar-Eli L (2002) Laboratory measures of impulsivity: a comparison of women with or without childhood aggression. Psychol Rec 52:289-303
82. Menkes DB, Coates DC, Fawcett JP (1994) Acute tryptophan depletion aggravates premenstrual syndrome. J Affect Disord 32:37-44 (Pubitemid 24277405)
83. Miller HE, Deakin JF, Anderson IM (2000) Effect of acute tryptophan depletion on CO2-induced anxiety in patients with panic disorder and normal volunteers. Br J Psychiatry 176:182-188 (Pubitemid 32734846)
84. Moeller FG, Dougherty DM (2001) Antisocial personality disorder, alcohol and aggression. Alcohol Res Health 25:5-11
85. Moja EA, Antinoro E, Cesa-Bianchi M, Gessa GL (1984) Increase in stage 4 sleep after ingestion of a tryptophan-free diet in humans. Pharmacol Res Commun 16:909-914 (Pubitemid 15147660)
86. Moja EA, Restani P, Corsini E, Stacchezzini MC, Asserto R, Galli CL (1991) Cycloheximide blocks the fall of plasma and tissue tryptophan levels after tryptophan-free amino acid mixtures. Life Sci 49:1121-1128
87. Moss HB (1987) Serotonergic activity and disinhibitory psychopathy in alcoholism. Med Hypotheses 23:353-361
88. Mulvihill LE, Skilling TA, Vogel-Sprott M (1997) Alcohol and the ability to inhibit behavior in men and women. J Stud Alcohol 58:600-605 (Pubitemid 27498055)
89. Munafo MR, Hayward G, Harmer C (2006) Selective processing of social threat cues following acute tryptophan depletion. J Psychopharmacol 20:33-39
90. Murphy FC, Smith KA, Cowen PJ, RobbinsTW, Sahakian BJ (2002) The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers. Psychopharmacology 163:42-53
91. Nishizawa S, Benkelfat C, Young SN, Leyton M, Mzengeza S, de Montigny C, Blier P, Diksic M (1997) Differences between males and females in rates of serotonin synthesis in human brain. Proc Natl Acad Sci USA 94:5308-5313 (Pubitemid 27214779)
92. Oosterlaan J, Logan GD, Sergeant JA (1998) Response inhibition in AD/HD, CD, comorbid AD/HD+CD, anxious, and control children: a meta-analysis of studies with the stop task. J Child Psychol Psychiatry 39:411-425 (Pubitemid 28112167)
93. Ortner CNM, MacDonald TK, Olmstead M (2003) Alcohol intoxication reduces impulsivity in the delay-discounting paradigm. Alcohol Alcohol 38:151-156
94. O'Toole K, Abramowitz A, Morris R, Dulcan MK (1997) Effects of methylphenidate and nonverbal learning in children with attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psych 36:531-538
95. Patton JH, Stanford MS, Barratt ES (1995) Factor structure of the Barratt Impulsiveness Scale. J Clin Psychol 51:768-774 (Pubitemid 26021724)
96. Pihl RO, Young SN, Harden P, Plotnick S, Chamberlain B, Ervin FR (1995) Acute effect of altered tryptophan levels and alcohol on aggression in normal human males. Psychopharmacology 119:353-360
97. Reilly JG, McTavish SFB, Young AH (1997) Rapid depletion of plasma tryptophan: a review of studies and experimental methodology. J Psychopharmacol 11:381-392 (Pubitemid 27526048)
98. Richards JB, Zhang L, Mitchell SH, de Wit H (1999) Delay or probability discounting in a model of impulsive behavior: effect of alcohol. J Exp Anal Behav 71:121-143
99. Riedel WJ, Sobczak S, Schmitt JA (2003) Tryptophan modulation and cognition. Adv Exp Med Biol 527:207-213 (Pubitemid 38197646)
100. Rogers RD, Blackshaw AJ, Middleton HC, Matthews K, Hawtin K, Crowley C, Hopwood A, Wallace C, Deakin JF, Sahakian BJ, Robbins TW (1999) Tryptophan depletion impairs stimulus-reward learning while methylphenidate disrupts attentional control in healthy young adults: implications for the monoaminergic basis of impulsive behaviour. Psychopharmacology 146:482-491 (Pubitemid 29513289)
101. Roiser JP, Muller U, Clark L, Sahakian BJ (2006) The effects of acute tryptophan depletion and serotonin transporter polymorphism on emotional processing in memory and attention. Int J Neuropsychopharmacol August 8, pp 1-13 [Epub ahead of print]
102. Rouanet H, Lepine D (1970) Comparison between treatments in a repeated-measurement design: ANOVA and multivariate methods. Br J Math Stat Psychol 23:147-163
103. Roy A, Linnoila M (1989) CSF studies on alcoholism and related behaviors. Prog Neuro-psychopharmacol Biol Psychiatry 13:505-511 (Pubitemid 19163799)
104. Rubinsztein JS, Rogers RD, Riedel WJ, Mehta MA, Robbins TW, Sahakian BJ (2001) Acute dietary tryptophan depletion impairs maintenance of "affective set" and delayed visual recognition in healthy volunteers. Psychopharmacology 154:319-326 (Pubitemid 32247193)
105. Sharma RP, Shapiro LE, Kamath SK, Soll EA, Watanabe MD, Davis JM (1997) Acute dietary tryptophan depletion: effects on schizophrenic positive and negative symptoms. Neuropsychobiology 35:5-10 (Pubitemid 27037716)
106. Smith SE, Pihl RO, Young SN, Ervin FR (1987) A test of possible cognitive and environmental influences on the mood lowering effect of tryptophan depletion in normal males. Psychopharmacology 91:451-457 (Pubitemid 17038208)
107. Stancampiano R, Melis F, Sarias L, Cocco S, Cugusi C, Fadda F (1997) Acute administration of a tryptophan-free amino acid mixture decreases 5-HT release in rat hippocampus in vivo. Reg Integ Comparat Physiol 41:R991-R994
108. Swann AC, Anderson J, Dougherty DM, Moeller FG (2001) Measurement of inter-episode impulsivity in bipolar disorder: a preliminary report. Psychiatry Res 101:195-197 (Pubitemid 32245802)
109. Sykes DH, Douglas VI, Weiss G, Minde KK (1971) Attention in hyperactive children and the effect of methylphenidate (Ritalin). J Child Psychol Psychiatry 12:129-139
110. Sykes DH, Douglas VI, Morgenstern G (1973) Sustained attention in hyperactive children. J Child Psychol Psychiatry 14:213-220
111. Taylor SP (1967) Aggressive behavior and physiological arousal as a function of provocation and the tendency to inhibit aggression. J Person 35:297-310
112. Taylor SP (1983) Alcohol and human physical aggression. In: Gottheil E, Druley KA, Skoloday TE, Waxman HM (eds) Alcohol, drug abuse and aggression. Charles C Thomas, Springfield, IL, pp 280-291
113. Thompson LL, Whitmore EA, Raymond KM, Crowley TJ (2006) Measuring impulsivity in adolescents with serious substance and conduct problems. Assessment 13:3-15 (Pubitemid 43812611)
114. Virkkunen M, Kallio E, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C, Bissette G, Kalogeras K, Karonen SL, Linnoila M (1994a) Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 51:28-33 (Pubitemid 24028995)
115. Virkkunen M, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C, Bissette G, Kalogeras K, Karonen SL, Linnoila M (1994b) CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 51:20-27 (Pubitemid 24028994)
116. Walderhaug E, Lunde H, Nordvik JE, Landrø NI, Refsum H, Magnusson A (2002) Lowering of serotonin by rapid tryptophan depletion increases impulsiveness in normal individuals. Psychopharmacology 164:385-391 (Pubitemid 35435714)
117. Weltzin TE, Fernstrom MH, Fernstrom JD, Neuberger SK, Kaye WH (1995) Acute tryptophan depletion and increased food intake and irritability in bulimia nervosa. Am J Psychiatry 152:1668-1671
118. Williams WA, Shoaf SE, Hommer D, Rawlings R, Linnoila M (1999) Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers. J Neurochem 72:1641-1647 (Pubitemid 29140839)
119. WIN, Weight-control Information Network (2006) Weight and waist measurement: Tools for adults. http://win.niddk.nih.gov/publications/tools.htm#bodymassindex. Accessed 1/31/07
120. Wolfe BE, Metzger ED, Jimerson DC (1995) Comparison of the effects of amino acid mixture and placebo on plasma tryptophan to large neutral amino acid ratio. Life Sci 56:1395-1400
121. Young SN (1993) The use of diet and dietary components in the study of factors controlling affect in humans: a review. J Psychiatry Neurosci 18:235-244
122. Young SN, Gauthier S (1981) Effect of tryptophan administration on tryptophan, 5-hydroxyindoleacetic acid, and indoleacetic acid in human lumbar and cisternal cerebrospinal fluid. J Neurol Neurosurg Psychiatry 44:323-327
123. Young SN, Ervin FR (1984) Cerebrospinal fluid measurements suggest precursor availability and sex are involved in the control of biogenic amine metabolism in a primate. J Neurochem 42:1570-1573 (Pubitemid 14085640)
124. Young SN, Leyton M (2002) The role of serotonin in human mood and social interaction: insight from altered tryptophan levels. Pharmacol Biochem Behav 71:857-865 (Pubitemid 34219235)
125. Young SN, Smith SE, Pihl RO, Ervin FR (1985) Tryptophan depletion causes a rapid lowering of mood in normal males. Psychopharmacology 87:173-177 (Pubitemid 16253342)
126. Young SN, Ervin FR, Pihl RO, Finn P (1989) Biochemical aspects of tryptophan depletion in primates. Psychopharmacology 98:508-511 (Pubitemid 19193899)