Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs

Journal of Veterinary Pharmacology and Therapeutics

Volumn 30, Issue 5, 2007, Pages 477-481

  Varzi, H N ^a   Esmailzadeh, S ^a   Morovvati, H ^a   Avizeh, R ^a   Shahriari, A ^a   Givi, M E ^a  

^a SHAHID CHAMRAN UNIVERSITY OF AHVAZ   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; GENTAMICIN; MALONALDEHYDE; SILYMARIN;

ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOG; DRUG EFFECT; DRUG MECHANISM; KIDNEY FUNCTION; MONOTHERAPY; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; UREA BLOOD LEVEL;

ANIMALS; ANTI-BACTERIAL AGENTS; BLOOD UREA NITROGEN; CREATININE; DOG DISEASES; DOGS; DRUG THERAPY, COMBINATION; GENTAMICINS; INJECTIONS, INTRAMUSCULAR; KIDNEY DISEASES; MALONDIALDEHYDE; MILK THISTLE; PHYTOTHERAPY; PROTECTIVE AGENTS; SILYMARIN; VITAMIN E;

CANIS FAMILIARIS; SILYBUM MARIANUM;

EID: 34548449346     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2007.00901.x     Document Type: Article

References (25)

1. Abdel-Naim, A.B., Abdel-Wahab, M.H. Attia, F.F. (1999) Protective effects of vitamin E and probucol against gentamicin-induced nephrotoxicity in rats. Pharmacological Research, 40, 183 187.
2. Ademuyiwa, O., Ngaha, E.O. Ubah, F.O. (1990) Vitamin E and selenium in gentamicin nephrotoxicity. Human Experimental Toxicology, 9, 281 288.
3. Ali, B.H. (2003) Agents ameliorating or augmenting experimental gentamicin nephrotoxicity: some recent research. Food Chemical Toxicology, 41, 1447 1452.
4. Chon, S.K. Kim, N.S. (2005) Evaluation of silymarin in the treatment on asymptomatic Giardia infections in dogs. Parasitological Research, 97, 445 451.
5. Cronin, R.E., Bulger, R.E, Southeru, P. Henrich, W.L. (1980) Natural history of aminoglycoside nephrotoxicity in the dog. Journal of Laboratory Clinical Medicine, 95, 463 474.
6. Cuzzocrea, S., Mazzon, E., Dugo, L., Serraino, I., Paola, R.D. Britti, D., Sarro, A.D. Pierpaoli, S., Caputi, A.P., Masini, E. Salvemini, D. (2002) A role for superoxide in gentamicin-mediated nephropathy in rats. European Journal of Pharmacology, 450, 67 76.
7. Davies, C., Forrester, S.D., Troy, G.C., Saunders, G.K., Shell, L.G. Johnston, S.A. (1998) Effects of a prostaglandin E1 analogue, misoprostol, on renal function in dogs receiving nephrotoxic doses of gentamicin. American Journal of Veterinary Research, 59, 1048 1054.
8. Fauconneau, B., Tallineau, C., Huguet, F. Piriou, A. (1995) Gentamicin-induced kidney damage and lipid peroxidation in rats. Toxicology Letters, 76, 127 134.
9. Flora, K., Hahn, M., Rosen, H. Benner, K. (1998) Milk thistle (silybum marianum) for the therapy of liver disease. The American Journal Gastroenterology, 93, 139 143.
10. Frazier, D.L. Riviere, J.E. (1987) Gentamicin dosing strategies for dogs with subclinical renal dysfunction. Antimicrobial Agents and Chemotherapy, 31, 1929 1934.
11. 1and TIMP-1. Journal of Hepatology, 35, 392 398.
12. Kadkhodaee, M., Khastar, H., Faghihi, M., Ghaznavi, R. Zahmatkesh, M. (2005) Effects of co-supplementation of vitamins E and C on gentamicin-induced nephrotoxicity in rat. Experimental Physiology, 90, 571 576.
13. Kavutcu, M., Canbolat, O., Ozturk, S., Olcay, E., Ulutepe, S., Ekinci, C., Gokhun, I.H. Durak, I. (1996) Reduced enzymatic antioxidant defense mechanism in kidney tissues from gentamicin-treated guinea pigs: effects of vitamins E and C. Nephron, 72, 269 274.
14. Koracevic, D., Koracevic, G., Djordjevic, V., Andrejevic, S. Cosic, V. (2001) Method for the measurement of antioxidant activity in human fluids. Journal of Clinical Pathology, 54, 356 361.
15. Kumar, K.V., Naidu, M.U.R., ShifowAnwar, A. Ratnakar, K.S. (2000) Probucol protects against gentamicin-induced nephrotoxicity in rats. Indian Journal of Pharmacology, 32, 108 113.
16. MacNeil, J.S., Jackson, B., Nelson, L. Butkas, D.E. (1983) The role of prostaglandins in gentamicin induced nephrotoxicity in the dogs. Nephron, 33, 202 207.
17. Mazzon, E., Britti, D., Sarro, A.D., Caputi, A. Cuzzocre, P.S. (2001) Effect of N-acetylcysteine on gentamicin-mediated nephropathy in rats. European Journal of Pharmacology, 424, 75 83.
18. Niehaus, W.G. Samuelsson, B. (1968) Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. European Journal of Biochemistry, 17, 126 130.
19. Oliveira, C., Lopasso, F.P., Laurindo, F., Leitao, R. Laundanna, A.A. (2001) Protection against liver ischemia-reperfusion injury in rats by silymarin or verapamil. Transplantation Proceeding, 33, 3010 3014.
20. Pares, A., Planas, R., Torres, M., Caballeria, J., Viver, J.M., Acero, D.J.P., Rigau, J.S.J. Rodes, J. (1998) Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial. Journal of Hepatology, 28, 615 621.
21. Pedraza-Chaverri, J., Gonza'lez-Orozco, A.E., Maldonado, P.D., Barrera, D., Medina-Campos, O.N. Herna'ndez-Pando, R. (2003) Diallyl disulfide ameliorates gentamicin-induced oxidative stress and nephropathy in rats. European Journal of Pharmacology, 473, 71 78.
22. Saller, R., Meier, R. Brignoli, R. (2001) The use of silymarin in the treatment of liver disease. Drugs, 61, 2034 2061.
23. Valdivielso, J.M., Rivas-Canabero, L., Perez-Barriocanal, F. Lopez-Novoa, J.M. (1997) Effect of nitric oxide synthesis modification on renal function in gentamicin-induced nephrotoxicity. Environmental Toxicology and Pharmacology, 3, 123 128.
24. Vladimir, K. Daniela, W. (2005) Silybin and silymarin - new effects and applications. Biomedical Papers, 149, 29 41.
25. Vogel, G., Tuchweber, B., Trost, W. Mengs, U. (1984) Protection by silibinin against Amanita phalloides intoxication in beagles. Toxicology and Applied Pharmacology, 73, 355 362.