Genetics of anxiety disorders. Current clinical and molecular research;Genetik der angsterkrankungen. Stand der klinischen und molekularen forschung

Nervenarzt

Volumn 78, Issue 7, 2007, Pages 825-835

  Domschke, K ^a   Deckert, J ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

Anxiety disorders; Complex disorders; Endophenotypes; Genetics; Panic disorder

Indexed keywords

ANXIETY DISORDER; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; GENETIC ANALYSIS; HUMAN; MOLECULAR GENETICS; NONHUMAN; PANIC; PHENOTYPE; POSTTRAUMATIC STRESS DISORDER; REVIEW;

ANXIETY DISORDERS; BIOMEDICAL RESEARCH; GENE THERAPY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MODELS, GENETIC; MODELS, NEUROLOGICAL; MOLECULAR BIOLOGY;

EID: 34548426458     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-007-2315-z     Document Type: Review

References (20)

1. Arnold PD, Zai G, Richter MA (2004) Genetics of anxiety disorders. Curr Psychiatry Rep 6: 243-254
2. Boulenger JP, Uhde TW, Wolff EA, Post RM (1984) Increased sensitivity to caffeine in patients with panic disorder. Arch Gen Psychiatry 41: 1067-1071
3. Cloninger CR, Van-Erdewegh P, Goate A et al. (1998) Anxiety proneness linked to epistatic loci in genome scan of human personality traits. Am J Med Genet 81: 313-317
4. Deckert J, Catalano M, Syagailo YV et al. (1999) Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder. Hum Mol Genet 8: 621-624
5. Domschke K, Braun M, Ohrmann P et al. (2006) Association of the functional -1019C/G 5-HT1A polymorphism with prefrontal cortex and amygdala activation measured with 3 T fMRI in panic disorder. Int J Neuropsychopharmacol 9: 349-355
6. Domschke K, Ohrmann P, Braun M et al. (2007) Influence of the catechol-O-methyltransferase val158met genotype on amygdala and orbitofrontal cortex emotional processing in panic disorder. Psychiatry Res Neuroimaging (im Druck)
7. Finn DA, Rutledge-Gorman MT, Crabbe JC (2003) Genetic animal models of anxiety. Neurogenetics 4: 109-135
8. Hettema JM, Neale MC, Kendler KS (2001) A review and meta-analysis of the genetic epidemiology of anxiety disorders. Am J Psychiatry 158: 1568-1578
9. Kendler KS, Karkowski LM, Prescott CA (1999) Fears and phobias: reliability and heritability. Psychol Med 29: 539-553
10. Klein DF (1964) Delineation of two drug responsive anxiety syndromes. Psychopharmacol 5: 397-408
11. Lesch KP, Bengel D, Heils A et al. (1996) Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274: 1483-1487
12. Maier W, Lichtermann D, Minges J, Heun R (1992) Personality traits in subjects at risk for unipolar major depression: a family study perspective. J Affect Disord 24: 153-163
13. Marks IM, Herst ER (1970) A survey of 1200 agoraphobics in Britain. Soc Psychiatry 5: 16-24
14. Rosenbaum JF, Biederman J, Hirshfield DR et al. (1991) Further evidence of an association between behavioral inhibition and anxiety disorders: results from a family study of children from a non-clinical sample. J Psychiatr Res 25: 49-65
15. Rowe DC, Stever C, Gard JM et al. (1998) The relation of the dopamine transporter gene (DAT1) to symptoms of internalizing disorders in children. Behav Genet 28: 215-225
16. Segman RH, Shalev AY (2003) Genetics of posttraumatic stress disorder. CNS Spectr 8: 693-698
17. Smoller JW, Acierno JS Jr, Rosenbaum JF et al. (2001) Targeted genome screen of panic disorder and anxiety disorder proneness using homology to murine QTL regions. Am J Med Genet 105: 195-206
18. Stein MB, Jang KL, Livesley WJ (1999) Heritability of anxiety sensitivity. Am J Psychiatry 156: 246-251
19. Van West D, Claes S (2004) The genetics of panic disorder: state of the art. Acta Neuropsychiatrica 16: 68-78
20. Zwanzger P, Deckert J (2007) Anxiety disorders: Causes, clinical picture and treatment. Nervenarzt 78: 349-360