Murine CTLL-2 cells respond to mIL12: Prospects for developing an alternative bioassay for measurement of murine cytokines IL12 and IL18

Journal of Immunological Methods

Volumn 326, Issue 1-2, 2007, Pages 41-53

  Khatri, Aparajita ^a   Husaini, Yasmin ^a   Russell, Pamela J ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Bioassays; CTLL 2; IL12; IL18; Synergy

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; NEUTRALIZING ANTIBODY;

ACCURACY; ANIMAL CELL; ARTICLE; ASSAY; BIOASSAY; CELL LINE; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; SPLEEN CELL; SUPERNATANT; T LYMPHOCYTE; UPREGULATION;

ANIMALS; CELL LINE; CELL PROLIFERATION; COLORIMETRY; HUMANS; IMMUNOLOGIC TESTS; INTERLEUKIN-12; INTERLEUKIN-18; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; RECEPTORS, INTERLEUKIN-12; RECEPTORS, INTERLEUKIN-18; T-LYMPHOCYTES; TETRAZOLIUM SALTS;

MURINAE; MUS;

EID: 34548398385     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2007.07.002     Document Type: Article

References (37)

1. Ahn H.J., Maruo S., Tomura M., Mu J., Hamaoka T., Nakanishi K., Clark S., Kurimoto M., Okamura H., and Fujiwara H. A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma. J. Immunol. 159 (1997) 2125
2. Baker P.E., Gillis S., and Smith K.A. Monoclonal cytolytic T-cell lines. J. Exp. Med. 149 (1979) 273
3. Boise L.H., McShan C.L., and Thompson C.B. Introduction of the cell survival gene bcl-xL improves the viability of CTLL-2 cells without affecting their IL-2 proliferative response. Implications for the development of bioassays. J. Immunol. Methods 191 (1996) 143
4. Burton J.D., Bamford R.N., Peters C., Grant A.J., Kurys G., Goldman C.K., Brennan J., Roessler E., and Waldmann T.A. A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 4935
5. Buttke T.M., McCubrey J.A., and Owen T.C. Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines. J. Immunol. Methods 157 (1993) 233
6. Chang J.T., Segal B.M., Nakanishi K., Okamura H., and Shevach E.M. The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit. Eur. J. Immunol. 30 (2000) 1113
7. Chung E.J., Choi S.H., Shim Y.H., Bang Y.J., Hur K.C., and Kim C.W. Transforming growth factor-beta induces apoptosis in activated murine T cells through the activation of caspase 1-like protease. Cell. Immunol. 204 (2000) 46
8. Deng G., and Podack E.R. Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 2189
9. Dinarello C.A. Interleukin-1beta. Crit. Care Med. 33 (2005) S460
10. Dinarello C.A., Orencole S.F., and Savage N. Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors. Adv. Exp. Med. Biol. 254 (1989) 45
11. Giglia J.S., Ovak G.M., Yoshida M.A., Twist C.J., Jeffery A.R., and Pauly J.L. Isolation of mouse T-cell lymphoma lines from different long-term interleukin 2-dependent cultures. Cancer Res. 45 (1985) 5027
12. Gillis S., and Smith K.A. Long term culture of tumour-specific cytotoxic T cells. Nature 268 (1977) 154
13. Hirano T., Akira S., Taga T., and Kishimoto T. Biological and clinical aspects of interleukin 6. Immunol. Today 11 (1990) 443
14. Hoshino T., Kawase Y., Okamoto M., Yokota K., Yoshino K., Yamamura K., Miyazaki J., Young H.A., and Oizumi K. Cutting edge: IL-18-transgenic mice: in vivo evidence of a broad role for IL-18 in modulating immune function. J. Immunol. 166 (2001) 7014
15. Ibelgaufts H. Cytokines Online Pathfinder Encyclopedia (COPE) (2002). http://www.copewithcytokines.de www.copewithcytokines.de
16. Li Q., Carr A.L., Donald E.J., Skitzki J.J., Okuyama R., Stoolman L.M., and Chang A.E. Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type 1 pattern. Cancer Res. 65 (2005) 1063
17. Liebau C., Merk H., Roesel C., Schmidt S., Karreman C., Prisack J.B., Bojar H., and Baltzer A.W. rIL-18 triggered gene therapy based on a transduction with the IL-12 plasmid: a new option as immuno-therapy for osteosarcoma?. Anticancer Res. 22 (2002) 2559
18. Liebau C., Roesel C., Schmidt S., Karreman C., Prisack J.B., Bojar H., Merk H., Wolfram N., and Baltzer A.W. Immunotherapy by gene transfer with plasmids encoding IL-12/IL-18 is superior to IL-23/IL-18 gene transfer in a rat osteosarcoma model. Anticancer Res. 24 (2004) 2861
19. Maruo S., Ahn H.J., Yu W.G., Tomura M., Wysocka M., Yamamoto N., Kobayashi M., Hamaoka T., Trinchieri G., and Fuijiwara H. Establishment of an IL-12-responsive T cell clone: its characterization and utilization in the quantitation of IL-12 activity. J. Leukoc. Biol. 61 (1997) 346
20. Meager A. Encyclopedia of Molecular cell Biology And Molecular Medicine vol. 3 (2004), Wiley-VCH, Weinheim, Germany 115
21. Meager A. Measurement of cytokines by bioassays: theory and application. Methods 38 (2006) 52-237
22. Mire-Sluis A.R., Gaines-Das R., and Thorpe R. Immunoassays for detecting cytokines: what are they really measuring?. J. Immunol. Methods 186 (1995) 157
23. Mire-Sluis A.R., Page L., and Thorpe R. Quantitative cell line based bioassays for human cytokines. J. Immunol. Methods 187 (1995) 191
24. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55
25. Roehm N.W., Rodgers G.H., Hatfield S.M., and Glasebrook A.L. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J. Immunol. Methods 142 (1991) 257
26. Russell C.A., and Vindelov L.L. Optimization and comparison of the MTT assay and the 3H-TdR assay for the detection of IL-2 in helper T cell precursor assays. J. Immunol. Methods 217 (1998) 165
27. Schoenhaut D.S., Chua A.O., Wolitzky A.G., Quinn P.M., Dwyer C.M., McComas W., Familletti P.C., Gately M.K., and Gubler U. Cloning and expression of murine IL-12. J. Immunol. 148 (1992) 3433
28. Tan A.S., and Berridge M.V. Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: a simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents. J. Immunol. Methods 238 (2000) 59
29. Taniguchi M., Nagaoka K., Ushio S., Nukada Y., Okura T., Mori T., Yamauchi H., Ohta T., Ikegami H., and Kurimoto M. Establishment of the cells useful for murine interleukin-18 bioassay by introducing murine interleukin-18 receptor cDNA into human myelomonocytic KG-1 cells. J. Immunol. Methods 217 (1998) 97
30. Tatsumi T., Huang J., Gooding W.E., Gambotto A., Robbins P.D., Vujanovic N.L., Alber S.M., Watkins S.C., Okada H., and Storkus W.J. Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity. Cancer Res. 63 (2003) 6378
31. Thompson T.C., Truong L.D., Timme T.L., Kadmon D., McCune B.K., Flanders K.C., Scardino P.T., and Park S.H. Transforming growth factor beta 1 as a biomarker for prostate cancer. J. Cell. Biochem., Suppl. 16H (1992) 54
32. Thompson T.C., Timme T.L., Kadmon D., Park S.H., Egawa S., and Yoshida K. Genetic predisposition and mesenchymal-epithelial interactions in ras + myc-induced carcinogenesis in reconstituted mouse prostate. Mol. Carcinog. 7 (1993) 165
33. Thompson T.C., Truong L.D., Timme T.L., Kadmon D., McCune B.K., Flanders K.C., Scardino P.T., and Park S.H. Transgenic models for the study of prostate cancer. Cancer 71 (1993) 1165
34. Tracey K.J., and Cerami A. Tumor necrosis factor, other cytokines and disease. Annu. Rev. Cell Biol. 9 (1993) 317
35. Weller M., Constam D.B., Malipiero U., and Fontana A. Transforming growth factor-beta 2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Eur. J. Immunol. 24 (1994) 1293
36. Weston L., Geczy A., and Farrell C. A convenient and reliable IL-2 bioassay using frozen CTLL-2 to improve the detection of helper T lymphocyte precursors. Immunol. Cell Biol. 76 (1998) 190
37. Yamanaka R., Tsuchiya N., Yajima N., Honma J., Hasegawa H., Tanaka R., Ramsey J., Blaese R.M., and Xanthopoulos K.G. Induction of an antitumor immunological response by an intratumoral injection of dendritic cells pulsed with genetically engineered Semliki Forest virus to produce interleukin-18 combined with the systemic administration of interleukin-12. J. Neurosurg. 99 (2003) 746