Downregulation of myosin II-B by siRNA alters the subcellular localization of the amyloid precursor protein and increases amyloid-β deposition in N2a cells

Biochemical and Biophysical Research Communications

Volumn 362, Issue 3, 2007, Pages 633-638

  Massone, Sara ^a   Argellati, Francesca ^a   Passalacqua, Mario ^a   Armirotti, Andrea ^a   Melone, Luca ^a   d'Abramo, Cristina ^a,b   Marinari, Umberto M ^a   Domenicotti, Cinzia ^a   Pronzato, Maria A ^a   Ricciarelli, Roberta ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Amyloid precursor protein (APP); Amyloid ; Myosin II

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; AMYLOID PRECURSOR PROTEIN; MYOSIN IIB; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; MOUSE; NERVE CELL; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SECRETION;

ALZHEIMER DISEASE; AMYLOID; ANIMALS; BIOTINYLATION; CELL MEMBRANE; CYTOSKELETON; GENE EXPRESSION REGULATION; HUMANS; MICE; MICROSCOPY, CONFOCAL; NEURONS; NONMUSCLE MYOSIN TYPE IIB; PROTEIN ISOFORMS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 34548381213     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.08.061     Document Type: Article

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