메뉴 건너뛰기




Volumn 49, Issue 1, 2007, Pages 53-62

Effects of MTBE on Leydig cell tumors in Sprague-Dawley rats: Range of possible Poly-3 results

Author keywords

Leydig cell tumor; MTBE; Poly 3 analysis; Prevalence analysis; Sprague Dawley rats

Indexed keywords

ETHER DERIVATIVE; GASOLINE;

EID: 34548378995     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2007.05.002     Document Type: Article
Times cited : (2)

References (35)
  • 1
    • 34548422973 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR), 1996. Toxicological profile for methyl tert-butyl ether. Research Triangle Institute: Research Triangle Park, VA.
  • 2
    • 0023677290 scopus 로고
    • Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples
    • Bailer A., and Portier C. Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples. Biometrics 44 2 (1988) 417-431
    • (1988) Biometrics , vol.44 , Issue.2 , pp. 417-431
    • Bailer, A.1    Portier, C.2
  • 3
    • 0028824089 scopus 로고
    • Methyl-tertiary-butyl ether (MTBE)-a gasoline additive-causes testicular and lymphohaematopoietic cancers in rats
    • Belpoggi F., Soffritti M., and Maltoni C. Methyl-tertiary-butyl ether (MTBE)-a gasoline additive-causes testicular and lymphohaematopoietic cancers in rats. Toxicol. Ind. Health 11 (1995) 119-149
    • (1995) Toxicol. Ind. Health , vol.11 , pp. 119-149
    • Belpoggi, F.1    Soffritti, M.2    Maltoni, C.3
  • 4
    • 0031587498 scopus 로고    scopus 로고
    • Results of long-term experimental studies on the carcinogenicity of methyl tert-butyl ether
    • Belpoggi F., Soffritti M., Filippini F., and Maltoni C. Results of long-term experimental studies on the carcinogenicity of methyl tert-butyl ether. Ann. NY Acad. Sci. 837 (1997) 77-95
    • (1997) Ann. NY Acad. Sci. , vol.837 , pp. 77-95
    • Belpoggi, F.1    Soffritti, M.2    Filippini, F.3    Maltoni, C.4
  • 5
    • 0000265108 scopus 로고    scopus 로고
    • Pathological characterization of testicular tumors and lymphomas-leukaemias, and of their precursors observed in Sprague-Dawley rats exposed to methyl-tertiary-butyl-ether (MTBE)
    • Belpoggi F., Soffritti M., and Maltoni C. Pathological characterization of testicular tumors and lymphomas-leukaemias, and of their precursors observed in Sprague-Dawley rats exposed to methyl-tertiary-butyl-ether (MTBE). Eur. J. Oncol. 3 (1998) 201-206
    • (1998) Eur. J. Oncol. , vol.3 , pp. 201-206
    • Belpoggi, F.1    Soffritti, M.2    Maltoni, C.3
  • 7
    • 34548408881 scopus 로고    scopus 로고
    • Chun, J.S., Burleigh-Flayer, H.D., Kintigh, W.J., 1992, November 13. Methyl tertiary butyl ether: Vapor inhalation oncogenicity study in Fischer 344 rats. Export, PA: Bushy Run Research Center.
  • 8
    • 0018828995 scopus 로고
    • Increase in Leydig cell number in testes of adult rats treated chronically with an excess of human chorionic gonadotropin
    • Christensen A.K., and Peacock K.C. Increase in Leydig cell number in testes of adult rats treated chronically with an excess of human chorionic gonadotropin. Biol. Reprod. 22 2 (1980) 383-391
    • (1980) Biol. Reprod. , vol.22 , Issue.2 , pp. 383-391
    • Christensen, A.K.1    Peacock, K.C.2
  • 9
    • 0030999939 scopus 로고    scopus 로고
    • Leydig cell hyperplasia and adenoma formation: mechanisms and relevance to humans
    • Clegg E.D., Cook J.C., Chapin R.E., Foster P.M., and Daston G.P. Leydig cell hyperplasia and adenoma formation: mechanisms and relevance to humans. Reprod. Toxicol. 22 1 (1997) 107-121
    • (1997) Reprod. Toxicol. , vol.22 , Issue.1 , pp. 107-121
    • Clegg, E.D.1    Cook, J.C.2    Chapin, R.E.3    Foster, P.M.4    Daston, G.P.5
  • 10
    • 0032903895 scopus 로고    scopus 로고
    • Rodent Leydig cell tumorigenesis: a review of the physiology, pathology, mechanisms, and relevance to humans
    • Cook J.C., Klinefelter G.R., Hardisty J.F., Sharpe R.M., and Foster P.M.D. Rodent Leydig cell tumorigenesis: a review of the physiology, pathology, mechanisms, and relevance to humans. Crit. Rev. Toxicol. 29 2 (1999) 169-261
    • (1999) Crit. Rev. Toxicol. , vol.29 , Issue.2 , pp. 169-261
    • Cook, J.C.1    Klinefelter, G.R.2    Hardisty, J.F.3    Sharpe, R.M.4    Foster, P.M.D.5
  • 11
    • 34548453321 scopus 로고    scopus 로고
    • Cruzan, G., Borghoff, S.J., de Peyster, A., Hard, G.C., McClain, M., McGregor, D.B., Thomas, M.G. 2006, November 2. Methyl tertiary-butyl ether mode of action for cancer endpoints in rodents. Regul Toxicol Pharmacol. [Epub ahead of print].
  • 12
    • 0034051919 scopus 로고    scopus 로고
    • Rodent carcinogenicity tests need be no longer than 18 months: an analysis based on 210 chemicals in the IARC monographs
    • Davies T.S., Lynch B.S., Monro A.M., Munro I.C., and Nestmann E.R. Rodent carcinogenicity tests need be no longer than 18 months: an analysis based on 210 chemicals in the IARC monographs. Food Chem. Toxicol. 38 2-3 (2000) 219-235
    • (2000) Food Chem. Toxicol. , vol.38 , Issue.2-3 , pp. 219-235
    • Davies, T.S.1    Lynch, B.S.2    Monro, A.M.3    Munro, I.C.4    Nestmann, E.R.5
  • 13
    • 0037340884 scopus 로고    scopus 로고
    • Subchronic studies in Sprague-Dawley rats to investigate mechanisms of MTBE-induced Leydig cell cancer
    • de Peyster A., MacLean K.J., Stephens B.A., Ahern L.D., Westover C.M., and Rozenshteyn D. Subchronic studies in Sprague-Dawley rats to investigate mechanisms of MTBE-induced Leydig cell cancer. Toxicol. Sci. 72 1 (2003) 31-42
    • (2003) Toxicol. Sci. , vol.72 , Issue.1 , pp. 31-42
    • de Peyster, A.1    MacLean, K.J.2    Stephens, B.A.3    Ahern, L.D.4    Westover, C.M.5    Rozenshteyn, D.6
  • 14
    • 34548396958 scopus 로고    scopus 로고
    • European Centre for Ecotoxicity and Toxicology of Chemicals (ECETOC), 2003. Risk assessment report for existing substances: methyl tertiary-butyl ether (Special Report No. 17). Brussels: European Centre for Ecotoxicity and Toxicology of Chemicals, 288p.
  • 15
    • 34548434472 scopus 로고    scopus 로고
    • European Chemicals Bureau (ECB), 2002. European Union risk assessment report: tert-butyl methyl ether (CAS No: 1634-04-4) (European Chemicals Bureau 3rd Priority list, volume 19). Luxembourgh: Office for Official Publications of the EC.
  • 16
    • 34548435361 scopus 로고    scopus 로고
    • European Food Safety Authority (EFSA), 2006. Opinion of the scientific panel on food additives, flavourings, processing aids, and materials in contact with food (AFC) on a request from the commission related to a new long-term carcinogenicity study on aspartame. Question number EFSA-Q-2005-122. Eur. Food Saf. Author. J., 356, 1-44. Retrieved from http://www.efsa.europa.eu/science/afc/afc_opinions/1471/afc_op_ej356_aspartame_en2.pdf.
  • 18
    • 33644810893 scopus 로고    scopus 로고
    • Recommendations for the interpretation of renal tubule proliferative lesions occurring in rat kidneys with advanced chronic progressive nephropathy (CPN)
    • Hard G.C., and Seely J.C. Recommendations for the interpretation of renal tubule proliferative lesions occurring in rat kidneys with advanced chronic progressive nephropathy (CPN). Toxicol. Pathol. 33 6 (2005) 641-649
    • (2005) Toxicol. Pathol. , vol.33 , Issue.6 , pp. 641-649
    • Hard, G.C.1    Seely, J.C.2
  • 19
    • 77957177404 scopus 로고
    • A reexamination of false-positive rates for carcinogenesis studies
    • Haseman J.K. A reexamination of false-positive rates for carcinogenesis studies. Fundam. Appl. Toxicol. 3 4 (1983) 334-339
    • (1983) Fundam. Appl. Toxicol. , vol.3 , Issue.4 , pp. 334-339
    • Haseman, J.K.1
  • 20
    • 34548458289 scopus 로고    scopus 로고
    • Commentary on 'Statistical methods for marcinogenicity studies
    • Haseman J.K. Commentary on 'Statistical methods for marcinogenicity studies. Toxicol. Pathol. 30 3 (2002) 405-408
    • (2002) Toxicol. Pathol. , vol.30 , Issue.3 , pp. 405-408
    • Haseman, J.K.1
  • 21
    • 0002903784 scopus 로고
    • Tumor incidences in Fischer 344 rats: NTP historical data
    • Boorman G.A., Eustis S.L., Elwell M.R., Montgomery C.A., and MacKenzie W.F. (Eds), Academic Press, San Diego, CA
    • Haseman J.K., Arnold J., and Eustis S.L. Tumor incidences in Fischer 344 rats: NTP historical data. In: Boorman G.A., Eustis S.L., Elwell M.R., Montgomery C.A., and MacKenzie W.F. (Eds). Pathology of the Fischer Rat: Reference and Atlas (1990), Academic Press, San Diego, CA 555-564
    • (1990) Pathology of the Fischer Rat: Reference and Atlas , pp. 555-564
    • Haseman, J.K.1    Arnold, J.2    Eustis, S.L.3
  • 22
    • 0015386365 scopus 로고
    • Statistical analysis of survival experiments
    • Hoel D.G., and Walburg H.E. Statistical analysis of survival experiments. J. Nat. Canc. Inst. 49 2 (1972) 361-372
    • (1972) J. Nat. Canc. Inst. , vol.49 , Issue.2 , pp. 361-372
    • Hoel, D.G.1    Walburg, H.E.2
  • 23
    • 34548433207 scopus 로고    scopus 로고
    • Interagency Regulatory Liaison Group (IRLG), 1979. Scientific bases for identification of potential carcinogens and estimation of risks. J. Nat. Cancer Inst., 244(25).
  • 24
    • 34548419034 scopus 로고    scopus 로고
    • International Agency for Research on Cancer (IARC), 1999. IARC monographs on the evaluation of carcinogenic risks to humans: Volume 73: Some chemicals that cause tumours of the kidney or urinary bladder in rodents and some other substances (IARC Monograph No. 73). Geneva: World Health Organization (WHO).
  • 25
    • 18444405219 scopus 로고    scopus 로고
    • Who will have the last word?
    • Maronpot R.R. Who will have the last word?. Toxicol. Pathol. 30 3 (2002) 297
    • (2002) Toxicol. Pathol. , vol.30 , Issue.3 , pp. 297
    • Maronpot, R.R.1
  • 26
    • 33646236591 scopus 로고    scopus 로고
    • Methyl tertiary-butyl ether: studies for potential human health hazards
    • McGregor D. Methyl tertiary-butyl ether: studies for potential human health hazards. Crit. Rev. Toxicol. 36 4 (2006) 319-358
    • (2006) Crit. Rev. Toxicol. , vol.36 , Issue.4 , pp. 319-358
    • McGregor, D.1
  • 28
    • 34548463167 scopus 로고    scopus 로고
    • National Toxicology Program (NTP), 2004. Descriptions of NTP study types: Expanded overview. Retrieved July 7, 2006 from http://ntp-server.niehs.nih.gov/ntpweb/index.cfm?objectid=72015E2C-BDB7-CEBA-F17F9ACA7AE5346D.
  • 29
    • 0034995191 scopus 로고    scopus 로고
    • Peto Analysis Working Group of STP. (2001). Draft recommendations on classification of rodent neoplasms for Peto analysis. Toxicol. Pathol., 29(2), 265-268.
  • 30
    • 0029055281 scopus 로고
    • A review of drug-induced Leydig cell hyperplasia and neoplasia in the rat and some comparisons with man
    • Prentice D.E., and Meikle A.W. A review of drug-induced Leydig cell hyperplasia and neoplasia in the rat and some comparisons with man. Hum. Exp. Toxicol. 14 (1995) 562-572
    • (1995) Hum. Exp. Toxicol. , vol.14 , pp. 562-572
    • Prentice, D.E.1    Meikle, A.W.2
  • 31
    • 0025695994 scopus 로고
    • Fourteen- and ninety-day oral toxicity studies of methyl tertiary-butyl ether in Sprague-Dawley rats
    • Robinson M., Bruner R.H., and Olson G.R. Fourteen- and ninety-day oral toxicity studies of methyl tertiary-butyl ether in Sprague-Dawley rats. J. Am. Coll. Toxicol. 9 5 (1990) 525-540
    • (1990) J. Am. Coll. Toxicol. , vol.9 , Issue.5 , pp. 525-540
    • Robinson, M.1    Bruner, R.H.2    Olson, G.R.3
  • 32
    • 0036960610 scopus 로고    scopus 로고
    • Ramazzini Foundation cancer program: history and major projects, life-span carcinogenicity bioassay design, chemicals studied, and results
    • Soffritti M., Belpoggi F., Minardi F., and Maltoni C. Ramazzini Foundation cancer program: history and major projects, life-span carcinogenicity bioassay design, chemicals studied, and results. Ann. NY Acad. Sci. 98 2 (2002) 26-45
    • (2002) Ann. NY Acad. Sci. , vol.98 , Issue.2 , pp. 26-45
    • Soffritti, M.1    Belpoggi, F.2    Minardi, F.3    Maltoni, C.4
  • 33
    • 34548389498 scopus 로고    scopus 로고
    • US Environmental Protection Agency (US EPA), 1997. Drinking water advisory: Consumer acceptability advice and health effects analysis on methyl tertiary-butyl ether (MtBE) (EPA-822-F-97-009). Office of Water: Washington, DC.
  • 34
    • 34548462737 scopus 로고    scopus 로고
    • US Food and Drug Administration (US FDA), Center for Drug Evaluation and Research, 2001. Guidance for industry: Statistical aspects of the design, analysis, and interpretation of chronic rodent carcinogenicity studies of pharmaceuticals. Retrieved November 18, 2006 from http://www.fda.gov/Cder/guidance/815dft.htm.
  • 35
    • 0034022926 scopus 로고    scopus 로고
    • Alterations in endocrine responses in male Sprague-Dawley rats following oral administration of methyl tert-butyl ether
    • Williams T.M., Cattley R.C., and Borghoff S.J. Alterations in endocrine responses in male Sprague-Dawley rats following oral administration of methyl tert-butyl ether. Toxicol. Sci. 54 (2000) 168-176
    • (2000) Toxicol. Sci. , vol.54 , pp. 168-176
    • Williams, T.M.1    Cattley, R.C.2    Borghoff, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.