Sympathetic vasoconstrictor regulation of mouse colonic submucosal arterioles is altered in experimental colitis

Journal of Physiology

Volumn 583, Issue 2, 2007, Pages 719-730

  Lomax, A E ^a   O'Reilly, M ^a   Neshat, S ^a   Vanner, S J ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; GUANETHIDINE; NUCLEOTIDASE; PHENYLEPHRINE; PRAZOSIN; PURINE P2X1 RECEPTOR; SURAMIN; TETRODOTOXIN; TRINITROBENZENESULFONIC ACID; PURINERGIC P2X1 RECEPTOR;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTERY CONSTRICTION; ARTICLE; CATABOLISM; COLITIS; COLON MUCOSA; CONTROLLED STUDY; ENZYME DEGRADATION; FREQUENCY MODULATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MICROSCOPY; MOUSE; NERVE STIMULATION; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURINERGIC NEUROTRANSMISSION; VIDEORECORDING; WESTERN BLOTTING; ANIMAL CELL; BLOOD VESSEL REACTIVITY; EVOKED RESPONSE; EXPERIMENTAL COLITIS; INTESTINE BLOOD FLOW; INTESTINE MUCOSA; NERVE POTENTIAL; SUBMUCOSA; SYMPATHETIC NERVE CELL; SYNAPTIC TRANSMISSION; VASOCONSTRICTION; VIDEO MICROSCOPY;

ADENOSINE TRIPHOSPHATE; ADRENERGIC AGENTS; ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ARTERIOLES; COLITIS; COLON; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; ENTERIC NERVOUS SYSTEM; GUANETHIDINE; INTESTINAL MUCOSA; MALE; MICE; MICROSCOPY, VIDEO; NOREPINEPHRINE; PHENYLEPHRINE; PRAZOSIN; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, PURINERGIC P2; SURAMIN; SYMPATHETIC NERVOUS SYSTEM; TETRODOTOXIN; TIME FACTORS; TRINITROBENZENESULFONIC ACID; UP-REGULATION; VASOCONSTRICTION;

EID: 34548355164     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.136838     Document Type: Article

References (41)

1. Anthony A (1999). Vascular anatomy in gastrointestinal inflammation. J Clin Pathol 52, 381-384.
2. Anthony A, Dhillon AP, Pounder RE & Wakefield AJ (1997). Ulceration of the ileum in Crohn's disease: Correlation with vascular anatomy. J Clin Pathol 50, 1013-1017.
3. Beyak MJ & Vanner S (2005). Inflammation-induced hyperexcitability of nociceptive gastrointestinal DRG neurones: The role of voltage-gated ion channels. Neurogastroenterol Motil 17, 175-186.
4. Bours MJ, Swennen EL, Di Virgilio F, Cronstein BN & Dagnelie PC (2006). Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 112, 358-404.
5. Burnstock G (2004). Cotransmission. Curr Opin Pharmacol 4, 47-52.
6. Burnstock G (2007). Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 87, 659-797.
7. Collins SM (1996). The immunomodulation of enteric neuromuscular function: Implications for motility and inflammatory disorders. Gastroenterology 111, 1683-1699.
8. Danese S, de la Sans MMC, Graziani C, West G, Phillips MH, Pola R, Rutella S, Willis J, Gasbarrini A & Fiocchi C (2006). Angiogenesis as a novel component of inflammatory bowel disease pathogenesis. Gastroenterology 130, 2060-2073.
9. Evans RJ & Surprenant A (1992). Vasoconstriction of guinea-pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP. Br J Pharmacol 106, 242-249.
10. Fiocchi C (1998). Inflammatory bowel disease: Etiology and pathogenesis. Gastroenterology 115, 182-205.
11. Gendron FP, Benrezzak O, Krugh BW, Kong Q, Weisman GA & Beaudoin AR (2002). Purine signaling and potential new therapeutic approach: possible outcomes of NTPDase inhibition. Curr Drug Targets 3, 229-245.
12. Gitterman DP & Evans RJ (2000). Properties of P2X and P2Y receptors are dependent on artery diameter in the rat mesenteric bed. Br J Pharmacol 131, 1561-1568.
13. Gitterman DP & Evans RJ (2001). Nerve evoked P2X receptor contractions of rat mesenteric arteries: Dependence on vessel size and lack of role of L-type calcium channels and calcium induced calcium release. Br J Pharmacol 132, 1201-1208.
14. Granger DN, Kvietis PR, Korthuis RJ & Premen AJ (1989). Microcirculation of the intestinal mucosa. In Handbook of Physiology, section 6, The Gastrointestinal System, vol. I, Motility and Circulation, ed. Wood JD, p p. 1405-1474. American Physiological Society, Bethesda, MD, USA.
15. Hatoum OA & Binion DG (2005). The vasculature and inflammatory bowel disease: Contribution to pathogenesis and clinical pathology. Inflamm Bowel Dis 11, 304-313.
16. Hatoum OA, Binion DG, Otterson MF & Gutterman DD (2003 a). Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation. Gastroenterology 125, 58-69.
17. Hatoum OA, Miura H & Binion DG (2003 b). The vascular contribution in the pathogenesis of inflammatory bowel disease. Am J Physiol Heart Circ Physiol 285, H1791-H1796.
18. Hirst GD, Choate JK, Cousins HM, Edwards FR & Klemm MF (1996). Transmission by post-ganglionic axons of the autonomic nervous system: the importance of the specialized neuroeffector junction. Neuroscience 73, 7-23.
19. Huidobro-Toro JP & Donoso MV (2004). Sympathetic co-transmission: the coordinated action of ATP and noradrenaline and their modulation by neuropeptide Y in human vascular neuroeffector junctions. Eur J Pharmacol 500, 27-35.
20. 2+ transients (jCaTs) in mesenteric small arteries. Am J Physiol Heart Circ Physiol 291, H3106-H3113.
21. 2+ currents mediated by neuropeptide Y Y2 receptors. J Smooth Muscle Res 35, 147-156.
22. 2+ signalling mechanisms in vascular myocytes: Symposium overview. Acta Physiol Scand 179, 339-352.
23. Li ZS, Fox-Threlkeld JE & Furness JB (1998). Innervation of intestinal arteries by axons with immunoreactivity for the vesicular acetylcholine transporter (VAChT). J Anat 192, 107-117.
24. Lomax AE, Fernandez E & Sharkey KA (2005 a). Plasticity of the enteric nervous system during intestinal inflammation. Neurogastroenterol Motil 17, 4-15.
25. Lomax AE, Mawe GM & Sharkey KA (2005 b). Synaptic facilitation and enhanced neuronal excitability in the submucosal plexus during experimental colitis in guinea-pig. J Physiol 564, 863-875.
26. Lourenssen S, Wells RW & Blennerhassett MG (2005). Differential responses of intrinsic and extrinsic innervation of smooth muscle cells in rat colitis. Exp Neurol 195, 497-507.
27. Lundgren O (1984). Microcirculation of the gastrointestinal tract, and pancreas. In Handbook of Physiology, section 2, The Cardiovascular System, vol IV, Microcirculation, ed. Renkin EM & Michel CC, pp. 799-863. American Physiological Society, Bethesda, MD, USA.
28. Mawe GM, Collins SM & Shea-Donohue T (2004). Changes in enteric neural circuitry and smooth muscle in the inflamed and infected gut. Neurogastroenterol Motil 16 (Suppl. 1), 133-136.
29. Moore BA, Stewart TM, Hill C & Vanner SJ (2002). TNBS ileitis evokes hyperexcitability and changes in ionic membrane properties of nociceptive DRG neurons. Am J Physiol Gastrointest Liver Physiol 282, G1045-G1051.
30. Mori M, Stokes KY, Vowinkel T, Watanabe N, Elrod JW, Harris NR, Lefer DJ, Hibi T & Granger DN (2005). Colonic blood flow responses in experimental colitis: Time course and underlying mechanisms. Am J Physiol Gastrointest Liver Physiol 289, G1024-G1029.
31. Neild TO (1989). Measurement of arteriole diameter changes by analysis of television images. Blood Vessels 26, 48-52.
32. Ralevic V & Burnstock G (1990). Postjunctional synergism of noradrenaline and adenosine 5′-triphosphate in the mesenteric arterial bed of the rat. Eur J Pharmacol 175, 291-299.
33. Strober W, Fuss IJ & Blumberg RS (2002). The immunology of mucosal models of inflammation. Annu Rev Immunol 20, 495-549.
34. Thompson LF, Eltzschig HK, Ibla JC, Van De Wiele CJ, Resta R, Morote-Garcia JC & Colgan SP (2004). Crucial role for ecto-5′-nucleotidase (CD73) in vascular leakage during hypoxia. J Exp Med 200, 1395-1405.
35. Thornton M & Solomon MJ (2002). Crohn's disease: In defense of a microvascular aetiology. Int J Colorectal Dis 17, 287-297.
36. Vanner S & Macnaughton WK (2004). Submucosal secretomotor and vasodilator reflexes. Neurogastroenterol Motil 16 (Suppl. 1), 39-43.
37. Vanner S & Surprenant A (1996). Neural reflexes controlling intestinal microcirculation. Am J Physiol Gastrointest Liver Physiol 271, G223-G230.
38. Vulchanova L, Arvidsson U, Riedl M, Wang J, Buell G, Surprenant A, North RA & Elde R (1996). Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc Natl Acad Sci U S A 93, 8063-8067.
39. Westfall DP, Todorov LD & Mihaylova-Todorova ST (2002). ATP as a cotransmitter in sympathetic nerves and its inactivation by releasable enzymes. J Pharmacol Exp Ther 303, 439-444.
40. Wirtz S, Neufert C, Weigmann B & Neurath MF (2007). Chemically induced mouse models of intestinal inflammation. Nat Protoc 2, 541-546.
41. Zernecke A, Bidzhekov K, Ozuyaman B, Fraemohs L, Liehn EA, Luscher-Firzlaff JM, Luscher B, Schrader J & Weber C (2006). CD73/ ecto-5′-nucleotidase protects against vascular inflammation and neointima formation. Circulation 113, 2120-2127.