Changes in enteric neural circuitry and smooth muscle in the inflamed and infected gut

Neurogastroenterology and Motility

Volumn 16, Issue SUPPL. 1, 2004, Pages 133-136

  Mawe, G M ^a   Collins, S M ^b   Shea Donohue, T ^c,d  

^a UNIVERSITY OF VERMONT   (United States)

^b MCMASTER UNIVERSITY   (Canada)

^c BELTSVILLE HUMAN NUTRITION RESEARCH CENTER   (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Cytokines; Enteric nervous system; Inflammation; Neuroplasticity; Postinfectious irritable bowel syndrome; Serotonin

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; SEROTONIN; TUMOR NECROSIS FACTOR ALPHA;

CELL SECRETION; CONFERENCE PAPER; DIARRHEA; DIGESTIVE SYSTEM INFLAMMATION; ENTERITIS; ENTEROCHROMAFFIN CELL; EPITHELIUM CELL; GASTROINTESTINAL INFECTION; GASTROINTESTINAL MOTILITY; GUINEA PIG; INTESTINE INNERVATION; INTESTINE SECRETION; MOTONEURON; NEUROMUSCULAR FUNCTION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SMOOTH MUSCLE; SMOOTH MUSCLE TONE;

ANIMALS; CYTOKINES; DIGESTIVE SYSTEM; ENTERIC NERVOUS SYSTEM; HUMANS; INFECTION; INFLAMMATION; MUSCLE, SMOOTH; NEURONS;

EID: 2342484969     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1743-3150.2004.00489.x     Document Type: Conference Paper

References (35)

1. Kirkup AJ, Brunsden AM, Grundy D. Receptors and transmission in the brain-gut axis: potential for novel therapies. I. Receptors on visceral afferents. Am J Physiol Gastrointest Liver Physiol 2001; 280: G787-94.
2. Raybould HE, Cooke HJ, Christofi F. Sensory mechanisms: transmitters, modulators and reflexes. Neurogastroenterol Motil 2004; 16 (Suppl. 1): 60-63.
3. Gershon MD. Roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther 1999; 13 (Suppl. 2): 15-30.
4. Spiller RC, Jenkins D, Thornley JP et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut 2000; 47: 804-11.
5. El-Salhy M, Danielsson A, Stenling R, Grimelius L. Colonic endocrine cells in inflammatory bowel disease. J Intern Med 1997; 242: 413-9.
6. Oshima S, Fujimura M, Fukimiya M. Changes in number of serotonin-containing cells and serotonin levels in the intestinal mucosa of rats with colitis induced by dextran sodium sulfate. Histochem Cell Biol 1999; 112: 257-63.
7. Linden DR, Chen JX, Gershon MD, Sharkey KA, Mawe GM. Serotonin availability is increased in mucosa of guinea pigs with TNBS-induced colitis. Am J Physiol Gastrointest Liver Physiol 2003; G207-16.
8. Palmer JM, Wong-Riley M, Sharkey KA. Functional alterations in jejunal myenteric neurons during inflammation in nematode-infected guinea pigs. Am J Physiol 1998; 275: G922-35.
9. Frieling T, Palmer JM, Cooke HJ, Wood JD. Neuroimmune communication in the submucous plexus of guinea pig colon after infection with Trichinella spiralis. J Auton Nerv Syst 1997; 66: 131-7.
10. Frieling T, Cooke HJ, Wood JD. Neuroimmune communication in the submucous plexus of guinea pig colon after sensitization to milk antigen. Am J Physiol 1994; 267: G1087-93.
11. Liu S, Hu HZ, Gao N et al. Neuroimmune interactions in guinea pig stomach and small intestine. Am J Physiol Gastrointest Liver Physiol 2003; 284: G154-64.
12. Linden DR, Sharkey KA, Mawe GM. Enhanced excitability of myenteric AH neurones in the inflamed guinea-pig distal colon. J Physiol 2003; 547: 589-601.
13. Reed DE, Barajas-Lopez C, Cottrell G et al. Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons. J Physiol 2003; 547: 531-42.
14. Linden DR, Manning BP, Bunnett NW, Mawe GM. Agonists of proteinase-activated receptor 2 excite guinea pig ileal myenteric neurons. Eur J Pharmacol 2001; 431: 311-4.
15. Linden DR, Sharkey KA, Ho W, Mawe GM. Cyclooxygenase-2 contributes to dysmotility and enhanced excitability of myenteric AH neurones in the inflamed guinea pig distal colon. J Physiol 2004; in press.
16. Manning BP, Sharkey KA, Mawe GM. Effects of PGE2 in guinea pig colonic myenteric ganglia. Am J Physiol Gastrointest Liver Physiol 2002; 283: G1388-97.
17. Shea-Donohue T, Goldhill JM, Montcalm-Mazzilli E, Colleton C, Pineiro-Carrero VM, Sjogren RW. Role of sensory afferents in the myoelectric response to acute enteric inflammation in the rabbit. Am J Physiol 1997; 273: G447-55.
18. Hosseini JM, Goldhill JM, Bossone C, Pineiro-Carrero V, Shea-Donohue T. Progressive alterations in circular smooth muscle contractility in TNBS-induced colitis in rats. Neurogastroenterol Motil 1999; 11: 347-56.
19. Morteau O, More J, Pons L, Bueno L. Platelet-activating factor and interleukin 1 are involved in colonic dysmotility in experimental colitis in rats. Gastroenterology 1993; 104: 47-56.
20. Vermillion DL, Huizinga JD, Riddell RH, Collins SM. Altered small intestinal smooth muscle function in Crohn's disease. Gastroenterology 1993; 104: 1692-9.
21. Schmitz H, Barmeyer C, Fromm M et al. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 1999; 116: 301-9.
22. Madara JL, Stafford J. Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers. J Clin Invest 1989; 83: 724-7.
23. Shea-Donohue TC, Sullivan FD et al. The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial cell function. J Immunol 2001; 167: 2234-9.
24. Madden KB, Whitman L, Sullivan C et al. Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function. J Immunol 2002; 169: 4417-22.
25. Di Leo V, Yang PC, Berin MC, Perdue MH. Factors regulating the effect of IL-4 on intestinal epithelial barrier function. Int Arch Allergy Immunol 2002; 129: 219-27.
26. Zhao A, McDermott J, Urban JF Jr et al. Dependence of IL-4, IL-13, and nematode-induced alterations in murine small intestinal smooth muscle contractility on Stat6 and enteric nerves. J Immunol 2003; 171: 948-54.
27. Akiho H, Blennerhassett P, Deng Y, Collins SM. Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 2002; 282: G226-32.
28. Goldhill J, Morris SC, Maliszewski C et al. Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle. Am J Physiol 1997; 272: G1135-40.
29. Fox CC, Lazenby AJ, Moore WC, Yardley JH, Bayless TM, Lichtenstein LM. Enhancement of human intestinal mast cell mediator release in active ulcerative colitis. Gastroenterology 1990; 99: 119-24.
30. Marzio L, Blennerhassett P, Chiverton S, Vermillion DL, Langer J, Collins SM. Altered smooth muscle function in worm-free gut regions of Trichinella-infected rats. Am J Physiol 1990; 259: G306-13.
31. Jacobson K, McHugh K, Collins SM. Experimental colitis alters myenteric nerve function at inflamed and noninflamed sites in the rat. Gastroenterology 1995; 109: 718-22.
32. Barbara G, Vallance BA, Collins SM. Persistent intestinal neuromuscular dysfunction after acute nematode infection in mice. Gastroenterology 1997; 113: 1224-32.
33. Spiller RC. Postinfectious irritable bowel syndrome. Gastroenterology 2003; 124: 1662-71.
34. Bossone C, Hosseini JM, Pineiro-Carrero V, Shea-Donohue T. Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon. Am J Physiol Gastrointest Liver Physiol 2001; 280: G949-57.
35. McCafferty DM, Wallace JL, Sharkey KA. Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rat. Am J Physiol 1997; 272: G272-80.