Role of histamine in ghrelin-induced gastroprotection against acute gastric lesions

Inflammation Research

Volumn 56, Issue SUPPL. 1, 2007, Pages

  Konturek, P C ^a   Brzozowski, T ^b   Konturek, S J ^b   Pawlik, M ^b   Gaca, P ^a   Hahn, E G ^a   Raithel, M ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CLOBENPROPIT; GHRELIN; HISTAMINE; RANITIDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; FOOD INTAKE; MALE; MOUSE; NONHUMAN; STOMACH LESION; STOMACH PARIETAL CELL; WISTAR RAT;

ANIMALS; ANTI-ULCER AGENTS; CYTOPROTECTION; ETHANOL; GASTRIC MUCOSA; HISTAMINE; HISTAMINE ANTAGONISTS; IMIDAZOLES; MALE; PEPTIDE HORMONES; RANITIDINE; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; THIOUREA;

EID: 34548349176     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-006-0512-z     Document Type: Conference Paper

References (6)

1. Peeters TL. Ghrelin: a new player in the control of gastrointestinal functions. Gut 2005; 54: 1638-49.
2. Date Y, Kojima M, Hosoda H, Sawaguchi A, Mondal MS, Suganuma T et al. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 2000; 141: 4255-61.
3. Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001; 50: 1714-9.
4. Konturek PC, Brzozowski T, Walter B, Burnat G, Hess T, Hahn EG et al. Ghrelin-induced gastroprotection against ischemia-reperfusion injury involves an activation of sensory afferent nerves and hyperemia mediated by nitric oxide. Eur J Pharmacol 2006; 536: 171-81.
5. Brzozowski T, Konturek PC, Konturek SJ, Kwiecien S, Drozdowicz D, Bielanski W et al. Exogenous and endogenous ghrelin in gastroprotection against stress-induced gastric damage. Regul Pept 2004; 120: 39-51.
6. Kwiecien S, Brzozowski T, Konturek PC, Konturek SJ, Pawlik M, Pajdo R et al. Effect of central and peripheral actions of histamine and its metabolite N-alpha methyl histamine on gastric secretion and acute gastric lesions. J Physiol Pharmacol 2001; 52: 625-38.