OL-protocadherin is essential for growth of striatal axons and thalamocortical projections

Nature Neuroscience

Volumn 10, Issue 9, 2007, Pages 1151-1159

  Uemura, Masato ^a   Nakao, Shinsuke ^a,b   Suzuki, Shintaro T ^c   Takeichi, Masatoshi ^a,b   Hirano, Shinji ^a,d  

^a RIKEN Center for Biosystems Dynamics Research   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KWANSEI GAKUIN UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; GLYCOPROTEIN; PROTEIN EMX2; PROTEIN OL PROTOCADHERIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; BRAIN SLICE; CONTROLLED STUDY; GLOBUS PALLIDUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRIATE CORTEX; TELENCEPHALON; THALAMOCORTICAL TRACT; THALAMUS; TRANSGENIC MOUSE;

ANIMALS; AXONS; BODY PATTERNING; CADHERINS; CEREBRAL CORTEX; CORPUS STRIATUM; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; NEURONS; THALAMUS;

EID: 34548324684     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1960     Document Type: Article

References (42)

1. Lopez-Bendito, G. & Molnar, Z. Thalamocortical development: how are we going to get there? Nat. Rev. Neurosci. 4, 276-289 (2003).
2. Garel, S. & Rubenstein, J.L. Intermediate targets in formation of topographic projections: inputs from the thalamocortical system. Trends Neurosci. 27, 533-539 (2004).
3. Hanashima, C., Molnar, Z. & Fishell, G. Building bridges to the cortex. Cell 125, 24-27 (2006).
4. Metin, C., Deleglise, D., Serafini, T., Kennedy, T.E. & Tessier-Lavigne, M. A role for netrin-1 in the guidance of cortical efferents. Development 124, 5063-5074 (1997).
5. Seibt, J. et al. Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues. Neuron 39, 439-452 (2003).
6. Dufour, A. et al. Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes. Neuron 39, 453-465 (2003).
7. Jones, L., Lopez-Bendito, G., Gruss, P., Stoykova, A. & Molnar, Z. Pax6 is required for the normal development of the forebrain axonal connections. Development 129, 5041-5052 (2002).
8. Lopez-Bendito, G., Chan, C.H., Mallamaci, A., Parnavelas, J. & Molnar, Z. Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus. J. Comp. Neurol. 451, 153-169 (2002).
9. Polleux, F. Genetic mechanisms specifying cortical connectivity: let's make some projections together. Neuron 46, 395-400 (2005).
10. Mitrofanis, J. & Guillery, R.W. New views of the thalamic reticular nucleus in the adult and the developing brain. Trends Neurosci. 16, 240-245 (1993).
11. Metin, C. & Godement, P. The ganglionic eminence may be an intermediate target for corticofugal and thalamocortical axons. J. Neurosci. 16, 3219-3235 (1996).
12. Molnar, Z., Adams, R. & Blakemore, C. Mechanisms underlying the early establishment of thalamocortical connections in the rat. J. Neurosci. 18, 5723-5745 (1998).
13. Tuttle, R., Nakagawa, Y., Johnson, J.E. & O'Leary, D.D. Defects in thalamocortical axon pathfinding correlate with altered cell domains in Mash-1-deficient mice. Development 126, 1903-1916 (1999).
14. Lopez-Bendito, G. et al. Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell 125, 127-142 (2006).
15. Molnar, Z. & Blakemore, C. How do thalamic axons find their way to the cortex? Trends Neurosci. 18, 389-397 (1995).
16. Hirano, S., Suzuki, S.T. & Redies, C. The cadherin superfamily in neural development: diversity, function and interaction with other molecules. Front. Biosci. 8, d306-d355 (2003).
17. Redies, C., Vanhalst, K. & Roy, F. d-Protocadherins: unique structures and functions. Cell. Mol. Life Sci. 62, 2840-2852 (2005).
18. Yamagata, K. et al. Arcadlin is a neural activity-regulated cadherin involved in long term potentiation. J. Biol. Chem. 274, 19473-19479 (1999).
19. Phillips, G.R. et al. γ-Protocadherins are targeted to subsets of synapses and intracellular organelles in neurons. J. Neurosci. 23, 5096-5104 (2003).
20. Wang, X. γ-Protocadherins are required for survival of spinal interneurons. Neuron 36, 843-854 (2002).
21. Hirano, S., Yan, Q. & Suzuki, S.T. Expression of a novel protocadherin, OL-protocadherin, in a subset of functional systems of the developing mouse brain. J. Neurosci. 19, 995-1005 (1999).
22. Luckner, R., Obst-Pernberg, K., Hirano, S., Suzuki, S.T. & Redies, C. Granule cell raphes in the developing mouse cerebellum. Cell Tissue Res. 303, 159-172 (2001).
23. Aoki, E., Kimura, R., Suzuki, S.T. & Hirano, S. Distribution of OL-protocadherin protein in correlation with specific neural compartments and local circuits in the postnatal mouse brain. Neuroscience 117, 593-614 (2003).
24. Muller, K., Hirano, S., Puelles, L. & Redies, C. OL-protocadherin expression in the visual system of the chicken embryo. J. Comp. Neurol. 470, 240-255 (2004).
25. Nakao, S. et al. Distribution of OL-protocadherin in axon fibers in the developing chick nervous system. Brain Res. Mol. Brain Res. 134, 294-308 (2005).
26. Nakashiba, T., Nishimura, S., Ikeda, T. & Itohara, S. Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mech. Dev. 111, 47-60 (2002).
27. Kimura, J. et al. Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. J. Neurosci. 25, 5097-5108 (2005).
28. Shinozaki, K. et al. Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development 129, 3479-3492 (2002).
29. Garel, S., Marin, F., Grosschedl, R. & Charnay, P. Ebf1 controls early cell differentiation in the embryonic striatum. Development 126, 5285-5294 (1999).
30. Garel, S., Yun, K., Grosschedl, R. & Rubenstein, J.L. The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development 129, 5621-5634 (2002).
31. Yun, K., Garel, S., Fischman, S. & Rubenstein, J.L. Patterning of the lateral ganglionic eminence by the Gsh1 and Gsh2 homeobox genes regulates striatal and olfactory bulb histogenesis and the growth of axons through the basal ganglia. J. Comp. Neurol. 461, 151-165 (2003).
32. Tissir, F., Bar, I., Jossin, Y., De Backer, O. & Goffinet, A.M. Protocadherin Celsr3 is crucial in axonal tract development. Nat. Neurosci. 8, 451-457 (2005).
33. Takeichi, M. The cadherin superfamily in neuronal connections and interactions. Nat. Rev. Neurosci. 8, 11-20 (2007).
34. Chen, X. & Gumbiner, B.M. Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity. J. Cell Biol. 174, 301-313 (2006).
35. Wattler, S., Kelly, M. & Nehls, M. Construction of gene targeting vectors from lambda KOS genomic libraries. BioTechniques 26, 1150-1156, 1158, 1160 (1999).
36. Okabe, M., Ikawa, M., Kominami, K., Nakanishi, T. & Nishimune, Y. 'Green mice' as a source of ubiquitous green cells. FEBS Lett. 407, 313-319 (1997).
37. Suto, F., Murakami, Y., Nakamura, F., Goshima, Y. & Fujisawa, H. Identification and characterization of a novel mouse plexin, plexin-A4. Mech. Dev. 120, 385-396 (2003).
38. Toresson, H., Potter, S.S. & Campbell, K. Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for Pax6 and Gsh2. Development 127, 4361-4371 (2000).
39. Inoue, T., Nakamura, S. & Osumi, N. Fate mapping of the mouse prosencephalic neural plate. Dev. Biol. 219, 373-383 (2000).
40. Kitsukawa, T. et al. Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron 19, 995-1005 (1997).
41. Hogan, B., Beddington, R., Costantini, F. & Lacy, E. Manipulating the Mouse Embryo: A Laboratory Manual 2nd edn. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1994).
42. Ulupinar, E., Datwani, A., Behar, O., Fujisawa, H. & Erzurumlu, R. Role of semaphorin III in the developing rodent trigeminal system. Mol. Cell. Neurosci. 13, 281-292 (1999).