Novel monoclonal antibodies for the investigation of PCH family proteins

Signal Transduction

Volumn 7, Issue 4, 2007, Pages 320-328

  Lettau, Marcus ^a   Beyer, Alyn ^a   Janssen, Ottmar ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Monoclonal antibodies; PCH protein family; Signal transduction; T lymphocytes; Vesicular transport

Indexed keywords

CD2 BINDING PROTEIN; CELL PROTEIN; DEATH RECEPTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD2BP1; MONOCLONAL ANTIBODY CIP4; MONOCLONAL ANTIBODY PACSIN1; POMBE CDC15 HOMOLOGY; PROLINE; PROTEIN CD178; PROTEIN CDC42; PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS 1; PROTEIN SH3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUSION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DRUG FORMULATION; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNIZATION; IMMUNODETECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSPORT VESICLE;

EID: 34548294257     PISSN: 16154053     EISSN: 16154061     Source Type: Journal    
DOI: 10.1002/sita.200600130     Document Type: Article

References (27)

1. Lippincott, J., Li, R. (2000) Involvement of PCH family proteins in cytokinesis and actin distribution. Microsc. Res. Tech. 49: 168-172.
2. Kessels, M.M., Qualmann, B. (2004) The syndapin protein family: linking membrane trafficking with the cytoskeleton. J. Cell Sci. 117: 3077-3086.
3. Aspenstrom, P., Fransson, A., Richnau, N. (2006) Pombe Cdc15 homology proteins: regulators of membrane dynamics and the actin cytoskeleton. Trends Biochem. Sci. 31: 670-679.
4. Aspenstrom, P. (1997) A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton. Curr. Biol. 7: 479-487.
5. Itoh, T., Erdmann, K.S., Roux, A., Habermann, B., et al. (2005) Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Dev. Cell 9: 791-804.
6. Tsujita, K., Suetsugu, S., Sasaki, N., Furutani, M., et al. (2006) Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis. J. Cell Biol. 172: 269-279.
7. Peter, B.J., Kent, H.M., Mills, I.G., Vallis, Y., et al. (2004) BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science 303: 495-499.
8. Kamioka, Y., Fukuhara, S., Sawa, H., Nagashima, K. et al. (2004) A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. J. Biol. Chem. 279: 40091-40099.
9. Tian, L., Nelson, D.L., Stewart, D.M. (2000) Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules. J. Biol. Chem. 275: 7854-7861.
10. Ho, H.Y., Rohatgi, R., Lebensohn, A.M., Le, M., et al. (2004) Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Cell 118: 203-216.
11. Li, J., Nishizawa, K., An, W., Hussey, R.E., et al. (1998) A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion. EMBO J. 17: 7320-7336.
12. Yang, H., Reinherz, E.L. (2006) CD2BP1 modulates CD2-dependent T cell activation via linkage to protein tyrosine phosphatase (PTP)-PEST. J. Immunol. 176: 5898-5907.
13. Badour, K., Zhang, J., Shi, F., McGavin, M.K., et al. (2003) The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. Immunity. 18: 141-154.
14. Wu, Y., Spencer, S.D., Lasky, L.A. (1998) Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein. J. Biol. Chem. 273: 5765-5770.
15. Qualmann, B., Roos, J., DiGregorio, P.J., Kelly, R.B. (1999) Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein. Mol. Biol. Cell 10: 501-513.
16. Hinshaw, J.E. (2000) Dynamin and its role in membrane fission. Annu. Rev. Cell Dev. Biol. 16: 483-519.
17. Sever, S., Damke, H., Schmid, S.L. (2000) Dynamim:GTP controls the formation of constricted coated pits, the rate limiting step in clathrin-mediated endocytosis. J. Cell Biol. 150: 1137-1148.
18. Ghadimi, M.P., Sanzenbacher, R., Thiede, B., Wenzel, J., et al. (2002) Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178). FEBS Lett. 519: 50-58.
19. Linkermann, A., Qian, J., Kabelitz, D., Janssen, O. (2003) The Fas ligand as a cell death factor and signal transducer. Signal Transduction 3: 33-46.
20. Janssen, O., Qian, J., Linkermann, A., Kabelitz, D. (2003) CD95 ligand-death factor and costimulatory molecule? Cell Death Differ. 10: 1215-1225.
21. Qian.J., Chen, W., Lettau, M., Podda, G., et al. (2006) Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL. Cell. Signal. 18: 1327-1337.
22. Lettau, M., Schmidt, H., Kabelitz, D., Janssen, O. (2007) Secretory lysosomes and their cargo in T and NK cells. Immunol. Lett. 108: 10-19.
23. Lettau, M., Qian, J., Kabelitz, D., Janssen, O. (2004) Activation-dependent FasL expression in T lymphocytes and Natural Killer cells. Signal Transduction 4: 206-211.
24. Lettau, M., Qian, J., Linkermann, A., Latreille, M. et al. (2006) The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse. Proc. Natl. Acad. Sci. U. S. A. 103: 5911-5916.
25. Baum, W., Kirkin, V., Fernandez, S.B., Pick, R., et al. (2005) Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL. J. Biol. Chem. 280: 40012-40024.
26. Badour, K., Zhang, J., Shi, F., Leng, Y., et al. (2004) Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation. J. Exp. Med. 199: 99-112.
27. Spencer, S., Dowbenko, D., Cheng, J., Li, W., et al. (1997) PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase. J. Cell Biol. 138: 845-860.