Hip fractures after stroke and their prevention

QJM: An International Journal of Medicine

Volumn 100, Issue 9, 2007, Pages 539-545

  Myint, P K ^a,b   Poole, K E S ^a   Warburton, E A ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; ANTIHYPERTENSIVE AGENT; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; ERGOCALCIFEROL; FOLIC ACID; MECOBALAMIN; PAMIDRONIC ACID; PLACEBO; RISEDRONIC ACID; SEDATIVE AGENT; VITAMIN D; ZOLEDRONIC ACID;

CARDIOVASCULAR FUNCTION; CLINICAL TRIAL; COST BENEFIT ANALYSIS; COST EFFECTIVENESS ANALYSIS; EPIDEMIOLOGICAL DATA; FALLING; FITNESS; HEMIPLEGIA; HIP FRACTURE; HUMAN; MUSCLE STRENGTH; OSTEOLYSIS; PATHOPHYSIOLOGY; PHYSIOTHERAPY; PRIORITY JOURNAL; PROTECTIVE EQUIPMENT; REIMBURSEMENT; RESPIRATORY FUNCTION; REVIEW; RISK ASSESSMENT; SIDE EFFECT; SINGLE DRUG DOSE; STROKE; SUN EXPOSURE;

EID: 34548226920     PISSN: 14602725     EISSN: 14602393     Source Type: Journal    
DOI: 10.1093/qjmed/hcm067     Document Type: Review

References (60)

1. Bamford J, Sandercock P, Dennis M, et al. A prospective study of acute cerebrovascular disease in the community: The Oxfordshire Community Stroke Project 1981-86. 1. Methodology, demography and incident cases of first-ever stroke. J Neurol Neurosurg Psychiatry 1988; 51:1373-80.
2. Rothwell PM, Coull AJ, Giles MF, et al. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet 2004; 363:1925-33.
3. Mulley G, Espley AJ. Hip fracture after hemiplegia. Postgrad Med J 1979; 55:264-5.
4. Jones G, Nguyen T, Sambrook P, Kelly PJ, Eisman JA. Progressive loss of bone in the femoral neck in elderly people: Longitudinal findings from the Dubbo osteoporosis epidemiology study. Br Med J 1994; 309 691-5.
5. Ensrud KE, Palermo L, Black DM, Cauley J, Jergas M, Orwoll ES, Nevitt MC, Fox KM, Cummings SR. Hip and calcaneal bone loss increase with advancing age: Longitudinal results from the study of osteoporotic fractures. J Bone Miner Res 1995; 10:1778-87.
6. Prince RL, Price RI, Ho S. Forearm bone loss in hemiplegia: A model for the study of immobilization osteoporosis. J Bone Miner Res 1988; 3:305-10.
7. Hamdy RC, Krisnaswamy G, Cancellaro V, Whalen K, Harvill L. Changes in bone mineral content and density after stroke. Am J Phys Med Rehabil 1993; 72:188-91.
8. Jorgensen L, Crabtree NJ, Reev J, Jacobsen BK. Ambulatory level and asymmetrical weight bearing after stroke affects bone loss in the upper and lower part of the femoral neck differently: Bone adaptation after decrease mechanical loading. Bone 2000; 27:701-7.
9. Ramnemark A, Nilsson M, Borssen B, Gustafson Y. Stroke, a major and increasing risk factor for femoral neck fracture. Stroke 2000; 31:1572-7.
10. Poole KES, Reeve J, Warburton EA. Falls, fractures, and osteoporosis after stroke. Time to think about protection? Stroke 2002; 33 1432-6.
11. Sato Y, Kuno H, Kaji M, Oizumi K. Influence of immobilization upon calcium metabolism in the week following hemiplegic stroke. J Neurol Sci 2000; 175:135-9.
12. Sato Y, Maruoka H, Honda Y, Asoh T, Fujimatsu Y, Oizumi K. Development of osteopenia in the hemiplegic finger in patients with stroke. Eur Neurol 1996; 36:278-83.
13. Jorgensen L, Jacobsen BK, Wilsgaard T, Magnus JH. Walking after stroke: does it matter? Changes in bone mineral density within the first 12 months after stroke: A longitudinal study. Osteoporos Int 2000; 11:381-7.
14. Sato Y, Marouka H, Oizumi K, Kikuyama M. Vitamin D deficiency and osteopenia in the hemiplegic limbs of stroke patients. Stroke 1996; 27:2183-7.
15. Sato Y, Kuno H, Asoh T, Honda Y, Oizumi K. Effect of immobilization on vitamin D status and bone mass in disabled elderly stroke patients. Age Ageing 1999; 28:265-9.
16. Sato Y, Honda Y, Kunoh K, Oizumi K. Long-term oral anticoagulation reduces bone mass in patients previous hemispheric infarction and nonrheumatic atrial fibrillation. Stroke 1997; 28:2390-4.
17. Demirbag D, Ozdemir F, Kokino S, Berkarda S. Ann Nucl Med 2005; 19:695-700.
18. Sato Y, Honda Y, Iwamoto J, Kanoka T, Satoh K. Homocysteine as predictive factor for hip fracture in stroke patients. Bone 2005; 36:721-6.
19. Poole KES, Warburton EA, Reeve J. Rapid long-term bone loss following stroke in a man with osteoporosis and atherosclerosis. Osteoporos Int 2005; 16:302-5.
20. Watanabe Y. An assessment of osteoporosis in stroke patient on rehabilitation admission. Int J Rehabil Res 2004; 27:163-6.
21. Christodoulou NA, Dretakis EK. Significance of muscular disturbances in the localization of fractures of the proximal femur. Clin Orthop Relate Res 1984; 187:215-17.
22. Chiu KY, Pun WK, Luk KD, Chow SP. A prospective study on hip fracture in patients with previous cerebrovascular accidents. Injury 1992; 23:297-9.
23. Ramnemark A, Nyberg L, Borssen B, Olsson T, Gustafson Y. Fractures after stroke. Osteoporos Int 1998; 8:92-5.
24. Dennis MS, Lo KM, McDowell M, West T. Fractures after stroke: Frequency, types, and associations. Stroke 2002; 33:728-34.
25. Kanis J, Oden A, Johnell O. Acute and long-term increase in fracture risk after hospitalisation for stroke. Stroke 2001; 32:702-6.
26. Davenport RJ, Dennis MS, Wellwood I, Warlow CP. Complication after acute stroke. Stroke 1996; 27:415-20.
27. Ugur C, Gucuyener D, Uzuner N, Ozkan S, Ozdemir G. Characteristics of falling in patients with stroke. J Neurol Neurosurg Psychiatry 2000; 69:649-51.
28. Nyberg L, Gustafson Y. Fall prediction index for patient in stroke rehabilitation. Stroke 1997; 28:716-21.
29. Dromerick A, Reding M. Medical and neurological complications during inpatient stroke rehabilitation. Stroke 1994; 25:358-61.
30. Briley DP, Haroon S, Sergent SM, Thomas S. Does leukoaraiosis predict morbidity and mortality? Neurology 2000; 54:90-4.
31. Forster A, Young J. Incidence and consequences of falls due to stroke: A systematic enquiry. Br Med J 1995; 311:83-6.
32. Langhorne P, Stott DJ, Robertson L, MacDonald J, Jones L, McAlpine C, Dick F, Taylor GS, Murray G. Medical complications after stroke: A multicenter study. Stroke 2000; 311:1223-9.
33. Mayo NE, Korner-Bitensky N, Kaizer F. Relationship between response time and falls among stroke patients undergoing physical rehabilitation. Int J Rehabil Res 1990; 13:47-55.
34. Salgado R, Lord SR, Packer J, Ehrlich F. Factors associated with falling in elderly hospital patients. Gerontology 1994; 40:325-31.
35. Cheng PT, Liaw MY, Wong MK, Tang FT, Lee MY, Lin PS. The sit-to-stand movement in stroke patients and its correlation with falling. Arch Phys Med Rehabil 1998; 79:1043-6.
36. Lamb SE, Ferrucci L, Volapto S, Fried LP, Guralnik JM. Risk Factors for Falling in Home-Dwelling Older Women With Stroke: The Women's Health and Aging Study. Stroke 2003; 34:494-501.
37. Sinaki M. Falls, fracture, and hip pads. Curr Osteoporos Rep 2004; 2:131-7.
38. Myint PK, Munim F, Woodhouse PR. Prevention of hip fracture: The role of hip protectors. Geriatr Med 2003; 33:63-9.
39. Willig R, Luukinen H, Jalovaara P. Factors related to occurrence of hip fracture during a fall on hip. Public Health 2003; 117:25-30.
40. Parker MJ, Gillespie WJ, Gillespie LD. Hip protectors for preventing hip fractures in older people. Cochrane Database Syst Rev 2005; 3 D001255.
41. Cameron ID, Stafford B, Cumming RG, Birks C, Kurrle SE, Lockwood K, Quine S, Finnegan T, Salkeld G. Hip protectors improve falls self-efficacy. Age Ageing 2000; 29:57-62.
42. Honkanen LA, Schackman BR, Mushlin AI, Lachs MS. A cost-benefit analysis of external hip protectors in the nursing home setting. J Am Geriatr Soc 2005; 53:190-7.
43. Parkkari J, Heikkila J, Kannus IP. Acceptability and compliance with wearing energy-shunting hip protectors: A 6-month prospective follow-up in a Finnish nursing home. Age Ageing 1998; 27:225-9.
44. Forsen L, Sandvig S, Schuller A, Sogaard AJ. Compliance with external hip protectors in nursing homes in Norway. Inj Prev 2004; 10 344-9.
45. Pang MY, Ashe MC, Eng JJ, McKay HA, Dawson AS. A 19-week exercise program for people with chronic stroke enhances bone geometry at the tibia: A peripheral quantitative computed tomography study. Osteoporos Int 2006; 17:1615-25.
46. Pang MY, Eng JJ, McKay HA, Dawson AS. Reduced hip bone mineral density is related to physical fitness and leg lean mass in ambulatory individuals with chronic stroke. Osteoporos Int 2005; 16 1769-79.
47. Pang MY, Eng JJ, Dawson AS, McKay HA, Harris JE. A community-based fitness and mobility exercise program for older adults with chronic stroke: A randomized controlled trial. J Am Geriatr Soc 2005; 53:1667-74.
48. Poole KE, Loveridge N, Barker PJ, Halsall DJ, Rose C, Reeve J, Warburton EA. Reduced vitamin D in acute stroke. Stroke 2006; 37:243-5.
49. Sato Y, Iwamoto J, Kanoko T, Satoh K. Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: A randomized controlled trial. Cerebrovasc Dis 2005; 20 187-92.
50. Sato Y, Iwamoto J, Kanoko T, Satoh K. Risedronate therapy for prevention of hip fracture after stroke in elderly women. Neurology 2005; 64:811-16.
51. Sato Y, Iwamoto J, Kanoko T, Satoh K. Risedronate sodium therapy for prevention of hip fracture in men 65 years or older after stroke. Arch Intern Med 2005; 165:1743-8.
52. Poole KES, Warburton EA, Reeve J. Residronate therapy for prevention of hip fracture in elderly women. Neurology 2005; 65:1513-14.
53. Poole KE, Loveridge N, Rose CM, Warburton EA, Reeve J. A single infusion of Zoledronate prevents bone loss after stroke. Stroke 2007; 38 1519-25.
54. van Meurs JB, Dhonukshe-Rutten RA, Pluijm SM, et al. Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med 2004; 350:2033-41.
55. Dhonukshe-Rutten RA, Pluijm SM, de Groot LC, Lips P, Smit JH, van Staveren WA. Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people. J Bone Miner Res 2005; 20:921-9.
56. Sacco RL, Anand K, Lee HS, Boden-Albala B, Stabler S, Allen R, Paik MC. Homocysteine and the risk of ischemic stroke in a triethnic cohort: The NOrthern MAnhattan Study. Stroke 2004; 35:2263-9.
57. Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K. Effect of Folate and Mecobalamin on Hip Fractures in Patients with Stroke. A Randomised Controlled Trial. JAMA 2005; 293:1082-8.
58. Bonaa KH, Njolstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T, Wang H, Nordrehaug JE, Arnesen E, Rasmussen K; NORVIT Trial Investigators. Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med 2006; 354:1578-88.
59. Kim YI. Role of folate in colon cancer development and progression. J Nutr 2003; 133(Suppl. 1):3731-9S.
60. Kim YI. Will mandatory folic acid fortification prevent or promote cancer? Am J Clin Nutr 2004; 80:1123-8.