Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts

Cancer Letters

Volumn 241, Issue 1, 2006, Pages 87-92

  Gunji, Akemi ^a,b   Uemura, Akiko ^a   Tsutsumi, Masahiro ^c   Nozaki, Tadashige ^a   Kusuoka, Osamu ^c   Omura, Ken ^b   Suzuki, Hiroshi ^d   Nakagama, Hitoshi ^a   Sugimura, Takashi ^a   Masutani, Mitsuko ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c NARA MEDICAL UNIVERSITY   (Japan)

^d CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

4 Nitroquinoline 1 oxide; Carcinogenesis; Knockout mice; Poly(ADP ribose) polymerase 1; Squamous cell carcinoma

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; CARCINOGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, HUMAN;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; ESOPHAGUS TUMOR; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; MOUSE; MOUSE MUTANT; MOUTH TUMOR; PATHOPHYSIOLOGY; PHYSIOLOGY;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; CARCINOGENS; ESOPHAGEAL NEOPLASMS; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; MOUTH NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES;

EID: 34548151570     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2005.10.003     Document Type: Article

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