Evaluation in vinyl chloride monomer-exposed workers and the relationship between liver lesions and gene polymorphisms of metabolic enzymes

World Journal of Gastroenterology

Volumn 11, Issue 37, 2005, Pages 5821-5827

  Zhu, Shou Min ^a   Ren, Xue Feng ^a   Wan, Jun Xiang ^a   Xia, Zhao Lin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Aldehyde dehydrogenase 2; Cytochrome p450 2E1; Glutathione S transferase; Hepatic lesions; Vinyl chloride monomer

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; CYTOCHROME P450 2E1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; UNCLASSIFIED DRUG; VINYL CHLORIDE;

ADULT; ARTICLE; CASE CONTROL STUDY; CHINA; CONFIDENCE INTERVAL; CONTROLLED STUDY; ECHOGRAPHY; FEMALE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HEMOGLOBINOPATHY; HUMAN; INCIDENCE; INDUSTRIAL WORKER; LIVER INJURY; MAJOR CLINICAL STUDY; MALE; NEURASTHENIA; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PATHOGENESIS; PHARYNX DISEASE; POLYMERASE CHAIN REACTION; PREVALENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; TOXICOKINETICS;

EID: 27944510600     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i37.5821     Document Type: Article

References (28)

1. Uzych L. Human male exposure to vinyl chloride and possible teratogenic and mutagenic risks: a review. Hum Toxicol 1988; 7: 517-527
2. Laplanche A, Clavel-Chapelon F, Contassot JC, Lanouziere C. Exposure to vinyl chloride monomer: results of a cohort study after a seven year follow up. The French VCM Group. Br J Ind Med 1992; 49: 134-137
3. John Luo JC, Cheng TJ, Du CL, Wang JD. Molecular epidemiology of plasma oncoproteins in vinyl chloride monomer workers in Taiwan. Cancer Detect Prev 2003; 27: 94-101
4. An evaluation of chemicals and industrial processes associated with cancer in humans based on human and animal data: IARC Monographs Volumes 1 to 20. Report of an IARC Working Group. Cancer Res 1980; 40: 1-12
5. Cheng TJ, Huang ML, You NC, Du CL, Chau TT. Abnormal liver function in workers exposed to low levels of ethylene dichloride and vinyl chloride monomer. J Occup Environ Med 1999; 41: 1128-1133
6. Dietz A, Langbein G, Permanetter W. Vinyl chloride induced hepatocellular carcinoma. Klin Wochenschr 1985; 63: 325-331
7. Du CL, Wang JD. Increased morbidity odds ratio of primary liver cancer and cirrhosis of the liver among vinyl chloride monomer workers. Occup Environ Med 1998; 55: 528-532
8. Mastrangelo G, Fedeli U, Fadda E, Valentini F, Agnesi R, Magarotto G, Marchi T, Buda A, Pinzani M, Martines D. Increased risk of hepatocellular carcinoma and liver cirrhosis in vinyl chloride workers: synergistic effect of occupational exposure with alcohol intake. Environ Health Perspect 2004; 112: 1188-1192
9. Ghissassi F, Barbin A, Bartsch H. Metabolic activation of vinyl chloride by rat liver microsomes: low-dose kinetics and involvement of cytochrome P450 2E1. Biochem Pharmacol 1998; 55: 1445-1452
10. Dosanjh MK, Chenna A, Kim E, Fraenkel-Conrat H, Samson L, Singer B. All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase. Proc Natl Acad Sci USA 1994; 91: 1024-1028
11. Guengerich FP. Roles of the vinyl chloride oxidation products 1-chlorooxirane and 2-chloroacetaldehyde in the in vitro formation of etheno adducts of nucleic acid bases. Chem Res Toxicol 1992; 5: 2-5
12. Cheng KC, Preston BD, Cahill DS, Dosanjh MK, Singer B, Loeb LA. The vinyl chloride DNA derivative N2,3-ethenoguanine produces G-A transitions in Escherichia coli. Proc Natl Acad Sci USA 1991; 88: 9974-9978
13. Wu X, Shi H, Jiang H, Kemp B, Hong WK, Delclos GL, Spitz MR. Association between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer. Carcinogenesis 1997; 18: 967-973
14. Li Y, Marion MJ, Ho R, Cheng TJ, Coulibaly D, Rosal R, Brandt-Rauf PW. Polymorphisms for vinyl chloride metabolism in French vinyl chloride workers. Int J Occup Med Environ Health 2003; 16: 55-59
15. Li Z, Tan W, Shao K. Susceptibility to lung cancer in Chinese is associated with genetic polymorphism in cytochrome P4502E1. Zhonghua Zhongliu Zazhi 2000; 22: 5-7
16. Wall TL, Peterson CM, Peterson KP, Johnson ML, Thomasson HR, Cole M, Ehlers CL. Alcohol metabolism in Asian-American men with genetic polymorphisms of aldehyde dehydrogenase. Ann Intern Med 1997; 127: 376-379
17. Wong NA, Rae F, Simpson KJ, Murray GD, Harrison DJ. Genetic polymorphisms of cytochrome p4502E1 and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a white population: a study and literature review, including meta-analysis. Mol Pathol 2000; 53: 88-93
18. Ambrosone CB, Sweeney C, Coles BF, Thompson PA, McClure GY, Korourian S, Fares MY, Stone A, Kadlubar FF, Hutchins LF. Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer. Cancer Res 2001; 61: 7130-7135
19. Guo JY, Wan DS, Zeng RP, Zhang Q. The polymorphism of GSTM1, mutagen sensitivity in colon cancer and healthy control. Mutat Res 1996; 372: 17-22
20. Murata M, Watanabe M, Yamanaka M, Kubota Y, Ito H, Nagao M, Katoh T, Kamataki T, Kawamura J, Yatani R, Shiraishi T. Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the Japanese population. Cancer Lett 2001; 165: 171-177
21. Harada S, Zhang S. New strategy for detection of ALDH2 mutant. Alcohol Alcohol Suppl 1993; 1: 11-13
22. Chen WJ, Loh EW, Hsu YP, Cheng AT. Alcohol dehydrogenase and aldehyde dehydrogenase genotypes and alcoholism among Taiwanese aborigines. Biol Psychiatry 1997; 41: 703-709
23. Wan J, Shi J, Hui L, Wu D, Jin X, Zhao N, Huang W, Xia Z, Hu G. Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning. Environ Health Perspect 2002; 110: 1213-1218
24. Huang CY, Huang KL, Cheng TJ, Wang JD, Hsieh LL. The GSTT1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function. Arch Toxicol 1997; 71: 482-488
25. Eaton DL. Biotransformation enzyme polymorphism and pesticide susceptibility. Neurotoxicology 2000; 21: 101-11
26. Chen WJ, Loh EW, Hsu YP, Chen CC, Yu JM, Cheng AT. Alcohol-metabolising genes and alcoholism among Taiwanese Han men: independent effect of ADH2, ADH3 and ALDH2. Br J Psychiatry 1996; 168: 762-767
27. Guengerich FP, Mason PS, Stott WT, Fox TR, Watanabe PG. Roles of 2-haloethylene oxides and 2-haloacetaldehydes derived from vinyl bromide and vinyl chloride in irreversible binding to protein and DNA. Cancer Res 1981; 41: 4391-4398
28. Takeshita T, Yang X, Inoue Y, Sato S, Morimoto K. Relationship between alcohol drinking, ADH2 and ALDH2 genotypes, and risk for hepatocellular carcinoma in Japanese. Cancer Lett 2000; 149: 69-76