Clonal interference is alleviated by high mutation rates in large populations

Molecular Biology and Evolution

Volumn 24, Issue 6, 2007, Pages 1397-1406

  Bollback, Jonathan P ^a   Huelsenbeck, John P ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adaptation; Clonal interference; Experimental evolution; Mutation

Indexed keywords

ARTICLE; ASEXUAL REPRODUCTION; CLONOGENESIS; GENETIC ANALYSIS; MUTATION RATE; NONHUMAN; POPULATION GENETICS; POPULATION SIZE; THEORETICAL STUDY; COMPARATIVE STUDY; GENETIC SELECTION; GENETICS; HAPLOTYPE; MOLECULAR EVOLUTION; MUTATION; POPULATION DENSITY;

EVOLUTION, MOLECULAR; GENETICS, POPULATION; HAPLOTYPES; MUTATION; POPULATION DENSITY; SELECTION (GENETICS);

EID: 34548104987     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msm056     Document Type: Article

References (28)

1. de Visser JAGM, Zeyl CW, Gerrish PJ, Blanchard JL, Lenski RE. 1999. Diminishing returns from mutation supply rate in asexual populations. Science. 283(5400):404-406.
2. de Visser JAGM, Rozen DE. 2005. Limits to adaptation in asexual populations. J Evol Biol. 18(4):779-788.
3. Drake J. 1993. Rates of spontaneous mutation rates among RNA viruses. Proc Natl Acad Sci USA. 90:4171-4175.
4. Drake JW, Charlesworth B, Charlesworth D, Crow JF. 1998. Rates of spontaneous mutation. Genetics. 148(4):1667-1686.
5. Fisher RA. 1930. The genetical theory of natural selection. Oxford (UK): Oxford University Press.
6. Gerrish PJ, Lenski RE. 1998. The fate of competing beneficial mutations in an asexual population. Genetica. 102:127-144.
7. Groenveld H, Thimon K, van Duin J. 1995. Translational control of maturation-protein synthesis in phage MS2: a role for the kinetics of RNA folding? RNA. 1:79-88.
8. Hill WC, Robertson A. 1968. Linkage disequilibrium in finite populations. Theor Appl Genet. 38:226-231.
9. Holder KK, Bull JJ. 2001. Profiles of adaptation in two similar viruses. Genetics. 159:1393-1404.
10. Imhof M, Schlötterer C. 2001. Fitness effects of advantageous mutations in evolving Escherichia coli populations. Proc Natl Acad Sci USA. 98(3):1113-1117.
11. Kim Y, Orr HA. 2005. Adaptation in sexuals vs. asexuals: clonal interference and the Fisher-Muller model. Genetics. 171(3):1377-1386.
12. Kloviņš J, Tsareva N, de Smit M, Berzins V, van Duin J. 1997. Rapid evolution of translational control mechanisms in RNA genomes. J Mol Biol. 265:372-384.
13. Maynard Smith J, Haigh J. 1974. The hitch-hiking effect of a favourable gene. Genet Res. 23:23-25.
14. Miralles RP, Gerrish PJ, Moya A, Elena SF. 1999. Clonal interference and the evolution of RNA viruses. Science. 285:1745-1747.
15. Muller HJ. 1932. Some genetic aspects of sex. Am Nat. 66:118-138.
16. Murphy FA, Fauquet CM, Bishop DHL, Ghabrial SA, Jarvis AW, Martelli GP, Mayo MA, Summers MD. 1995. Virus taxonomy: the classification and nomenclature of viruses. The sixth report of the international committee on taxonomy of viruses. Vienna (Austria): Springer-Verlag.
17. Orr HA. 2000. The rate of adaptation in asexuals. Genetics. 155:961-968.
18. Palasingam K, Shaklee PN. 1992. Reversion of Qβ RNA phage mutants by homologous RNA recombination. J Virol. 66:2435-2442.
19. Piganeau G, Eyre-Walker A. 2004. A reanalysis of the indirect evidence for recombination in human mitochondrial DNA. Heredity. 92(4):282-288.
20. R Development Core Team. 2005. R: a language and environment for statistical computing. Vienna (Austria): R Foundation for Statistical Computing.
21. Raney JL, Delongchamp RR, Valentine CR. 2004. Spontaneous mutant frequency and mutation spectrum for gene A of phiX174 grown in E. coli. Environ Mol Mutagen. 44(2): 119-127.
22. Sanjuán R, Cuevas JM, Moya A, Elena SF. 2005. Epistasis and the adaptability of an RNA virus. Genetics. 170(3): 1001-1008.
23. Sanjuán R, Elena SF. 2006. Epistasis correlates to genomic complexity. Proc Natl Acad Sci USA. 103(39):14402-14405.
24. Schmidt B, Berkhout , Overbeek GB, van Strien A, van Duin J. 1987. Determination of the RNA secondary structure that regulates lysis gene expression in bacteriophage MS2. J Mol Biol. 195:505-516.
25. Valegård K, Murray JB, Stockley PG, Stonehouse NJ, Liljas L. 1994. Crystal structure of an RNA bacteriophage coat protein-operatorcomplex. Nature. 371(6498):623-626.
26. van Himbergen J, van Geffen B, van Duin J. 1993. Translational control by a long range RNA-RNA interaction; a base substitution analysis. Nucleic Acids Res. 21:1713-1717.
27. Wichman HA, Badgett MR, Scott LA, Boulianne CM, Bull JJ. 1999. Different trajectories of parallel evolution during viral adaptation. Science. 285:422-424.
28. Wilke CO. 2004. The speed of adaptation in large asexual populations. Genetics. 167(4):2045-2053.