Synthesis, analgesic and anti-inflammatory activity of 4-(2-phenoxyphenyl) semicarbazones

Archiv der Pharmazie

Volumn 340, Issue 8, 2007, Pages 409-415

  Rineh, Ardeshir ^a   Mahmoodi, Nosratollah ^a   Abdollahi, Mohammad ^b   Foroumadi, Alireza ^b   Sorkhi, Maedeh ^b   Shafiee, Abbas ^b  

^a UNIVERSITY OF GUILAN   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Analgesic activity; Anti inflammatory activity; Semicarbazones

Indexed keywords

1 (2 CHLOROBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (2 HYDROXYBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (2 NITROBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (3 CHLOROBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (3 HYDROXYBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (3 NITROBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (4 CHLOROBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (4 HYDROXYBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (4 METHYLBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 (4 NITROBENZYLIDENE) 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (2 CHLOROPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (2 NITROPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (2,5 DIMETHOXYPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (3 BROMOPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (3 CHLOROPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (3 NITROPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (4 BROMOPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (4 CHLOROPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (4 METHOXYPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 1 [1 (4 NITROPHENYL)ETHYLIDENE] 4 (2 PHENOXYPHENYL)SEMICARBAZIDE; 4 (2 PHENOXYPHENYL)SEMICARBAZONE DERIVATIVE; ANTIINFLAMMATORY AGENT; FORMALDEHYDE; INDOMETACIN; MEFENAMIC ACID; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; MALE; RATS; RATS, WISTAR; SEMICARBAZONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34548101903     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200700045     Document Type: Article

References (15)

1. B. Tozkoparan, N. Gokhan, G. Aktay, E. Yesilada, M. Ertan, Eur. J. Med. Chem. 2000, 35, 743-750.
2. H. P. Rang, S. Bevan, A. Dray, Brit. Med. Bull. 1991, 47, 534-548.
3. J. D. Levine, W. Lau, G. Kwiat, E. J. Goetzl, Science 1984, 225, 743-745.
4. P. M. Vaananen, C. M. Keenan, M. B. Grisham, J. L. Wallace, Inflammation 1992, 16, 227-240.
5. M. D. Mullican, M. W. Wilson, D. T. Connor, C. R. Kostlan, et al., J. Med. Chem. 1993, 36, 1090-1099.
6. J. P. Mahy, S. Gaspard, D. Mansuy, Biochemistry 1993, 32, 4014-4021.
7. D. Sincholle, C. Bertez, A. Legrand, J. P. Conduzorgues, C. Bonne, Arzneim-Forsch. 1985, 35, 1260-1263.
8. M. R. L. Santos, E. J. Barreiro, R. Braz-Filho, A. L. P. Miranda, J. Braz. Chem. Soc. 1997, 8, 471-478.
9. I. G. Ribeiro, K. C. M. Da Silva, S. C. Prrini, A. L. P. De Miranda, et al., Eur. J. Med. Chem. 1998, 33, 225-235.
10. J. M. Figueirdo, C. A. Camara, E. G. Amarante, A. L. P. Miranda, et al., Bioorg. Med. Chem. 2000, 8, 2243-2248.
11. A. Almasirad, M. Sheikhha, R. Hosseini, S. A. Tabatabai, A. Shafiee, Arch. Pharm. Pharm. Med. Chem. 2004, 337, 193-200.
12. A. Almasirad, M. Tajik, D. Bakhtiari, A. Shafiee, et al., J. Pharm. Pharm. Sci. 2005, 8, 419-425.
13. A. Almasirad, R. Hosseini, H. Jalalizadeh, Z. Rahimi-Moghaddam, et al., Biol. Pharm. Bull. 2006, 29, 1180-1185.
14. D. Dubuisson, S. G. Dennis, Pain 1997, 4, 161-174.
15. H. A. Al-Haboubi, I. J. Zeitlin, Eur. J. Pharmacol. 1983, 88, 160-176.