Stress as a risk factor in the pathogenesis of rheumatoid arthritis

NeuroImmunoModulation

Volumn 13, Issue 5-6, 2007, Pages 277-282

  Cutolo, Maurizio ^a   Straub, Rainer H ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Autoimmune rheumatic diseases; Cortisol; Norepinephrine; Rheumatoid arthritis; Stress; Stress response system

Indexed keywords

BETA ADRENERGIC RECEPTOR; CD3 ANTIGEN; CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 6; NORADRENALIN; TUMOR NECROSIS FACTOR;

ADRENERGIC SYSTEM; AUTOIMMUNE DISEASE; BRAIN FUNCTION; CHRONIC STRESS; DISASTER; HORMONE RELEASE; HUMAN; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNE SYSTEM; INFLAMMATION; LIFE EVENT; LOCUS CERULEUS; MACROPHAGE; NEUROTRANSMISSION; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; RISK ASSESSMENT; RISK FACTOR; STRESS; T LYMPHOCYTE;

ANIMALS; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; PITUITARY-ADRENAL SYSTEM; RISK FACTORS; STRESS, PSYCHOLOGICAL;

EID: 34548092137     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000104855     Document Type: Review

References (42)

1. Straub RH, Cutolo M: Does stress influence the course of rheumatic diseases? Clin Exp Rheumatol 2006;24:225-228.
2. Dhabhar FS, McEwen BS: Enhancing versus suppressive effects of stress hormones on skin immune function. Proc Natl Acad Sci USA 1999;96:1059-1064.
3. Padgett DA, Glaser R: How stress influences the immune response. Trends Immunol 2003;24:444-448.
4. Elenkov IJ, Chrousos GP: Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann NY Acad Sci 2002;966:290-303.
5. Straub RH, Dhabhar FS, Bijlsma JW, Cutolo M: How psychological stress via hormones and nerve fibers may exacerbate rheumatoid arthritis. Arthritis Rheum 2005;52:16-12.
6. Herrmann M, Schölmerich J, Straub RH: Stress and rheumatic diseases. Rheum Dis Clin North Am 2000;26:8-27.
7. Chrousos GP: The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 1995;332:1351-1362.
8. Walker JG, Littlejohn GO, McMurray NE, Cutolo M: Stress system response and rheumatoid arthritis: a multilevel approach. Rheumatology (Oxford) 1999;38:1050-1057.
9. Cutolo M, Prete C, Walker J: Is stress a factor in the pathogenesis of autoimmune rheumatic diseases? Clin Exp Rheumatol 1999;17:515-518.
10. Del Rey A, Besedovsky HO: The cytokine-HPA axis circuit contributes to prevent or moderate autoimmune processes. Z Rheumatol 2000;59(suppl 2):II31-II35.
11. Zautra AJ, Hoffman JM, Matt KS, Yocum D, Potter PT, Castro WL, Roth S: An examination of individual differences in the relationship between interpersonal stress and disease activity among women with rheumatoid arthritis. Arthritis Care Res 1998;11:271-279.
12. Feigenbaum SL, Masi AT, Kaplan SB: Prognosis in rheumatoid arthritis: a longitudinal study of newly diagnosed younger adult patients. Am J Med 1979:66:377-384.
13. Dekkers JC, Geenen R, Evers AW, Kraaimaat FW, Bijlsma JW, Godaert GL: Biopsychosocial mediators and moderators of stress-health relationships in patients with recently diagnosed rheumatoid arthritis. Arthritis Rheum 2001;45:307-316.
14. Herrmann M, Scholmerich J, Straub RH: Stress and rheumatic diseases. Rheum Dis Clin North Am 2000;26:737-763.
15. Munck A, Guypre PM: Glucocorticoid physiology, pharmacology and stress. Adv Exp Med Biol 1986;196:81-96.
16. Webster JI, Tonelli L, Sternberg EM: Neuroendocrine regulation of immunity. Annu Rev Immunol 2002;20:125-163.
17. Buttgereit F, Straub RH, Wehling M, Burmester GR: Glucocorticoids in the treatment of rheumatic diseases: an update on the mechanisms of action. Arthritis Rheum 2004;50:3408-3417.
18. Cooper DA, Duckett M, Petts V, Penny R: Corticosteroid enhancement of immunoglobulin synthesis by pokeweed mitogen-stimulated human lymphocytes. Clin Exp Immunol 1979;37:145-151.
19. Wiegers GJ, Lauber MS, Stec IE, Klinkert WE, Holsboer F, Reul JM: Glucocorticoids accelerate anti-T cell receptor-induced T cell growth. J Immunol 1995;155:1893-1902.
20. Broug-Holub E, Kraal G: Dose- and time-dependent activation of rat alveolar macrophages by glucocorticoids. Clin Exp Immunol 1996;104:332-336.
21. Barber AE, Coyle SM, Marano MA, Fischer E, Calvano SE, Fong Y, Moldawer LL, Lowry SF: Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. J Immunol 1993;150:1999-2006.
22. Madden KS: Catecholamines, sympathetic nerves, and immunity; in Ader R, Felten DL, Cohen N (eds): Psychoneuroimmunology. San Diego, Academic Press, 2001, pp 197-216.
23. Spengler RN, Chensue SW, Giacherio DA, Blenk N, Kunkel SL: Endogenous norepinephrine regulates tumor necrosis factor-α production from macrophages in vitro. J Immunol 1994;152:3024-3031.
24. Lappin D, Whaley K: Adrenergic receptors on monocytes modulate complement component synthesis. Clin Exp Immunol 1982;47:606-612.
25. Straub RH, Günzler C, Miller LE, Cutolo M, Schölmerich J, Schill S: Anti-inflammatory cooperativity of corticosteroids and norepinephrine in rheumatoid arthritis synovial tissue in vivo and in vitro. FASEB J 2002;16:993-1000.
26. Crofford LJ, Kalogeras KT, Mastorakos G, Magiakou MA, Wells J, Kanik KS, Gold PW, Chrousos GP, Wilder RL: Circadian relationships between interleukin (IL)-6 and hypothalamic-pituitary-adrenal axis hormones: failure of IL-6 to cause sustained hypercortisolism in patients with early untreated rheumatoid arthritis. J Clin Endocrinol Metab 1997;82:1279-1283.
27. Cutolo M, Foppiani L, Prete C, Ballarino P, Sulli A, Villaggio B, Seriolo B, Giusti M, Accardo S: Hypothalamic-pituitary-adrenocortical axis function in premenopausal women with rheumatoid arthritis not treated with glucocorticoids. J Rheumatol 1999;26:282-288.
28. Straub RH, Pongratz G, Schölmerich J, Kees F, Schaible TF, Antoni C, Kalden JR, Lorenz HM: Long-term anti-tumor necrosis factor antibody therapy in rheumatoid arthritis patients sensitizes the pituitary gland and favors adrenal androgen secretion. Arthritis Rheum 2003;48:1504-1512.
29. Cutolo M, Villaggio B, Otsa K, Aakre O, Sulli A, Seriolo B: Altered circadian rhythms in rheumatoid arthritis patients play a role in the disease's symptoms. Autoimmun Rev 2005;4:497-502.
30. Eijsbouts AM, Van Den Hoogen FH, Laan RF, Hermus AR, Sweep CG, Van De Putte LB: Hypothalamic-pituitary-adrenal axis activity in patients with rheumatoid arthritis. Clin Exp Rheumatol 2005;23:658-664.
31. Pool AJ, Whipp BJ, Skasick AJ, Alavi A, Bland JM, Axford JS: Serum cortisol reduction and abnormal prolactin and corticosteroids and CD4+/CD8+ T-cell response as a result of controlled exercise in patients with rheumatoid arthritis and systemic lupus erythematosus despite unaltered muscle energetics. Rheumatology (Oxford) 2004;43:43-48.
32. Harbuz MS, Korendowych E, Jessop DS, Crown AL, Lightman SL, Kirwan JR: Hypothalamo-pituitary-adrenal axis dysregulation in patients with rheumatoid arthritis after the dexamethasone/corticotrophin releasing factor test. J Endocrinol 2003;178:55-60.
33. Straub RH, Kittner JM, Heinjen C, Schedowsky M, Schmidt RE, Jacobs R: Infusion of epinephrine decreases serum levels of cortisol and 17-hydroxyprogesterone in patients with rheumatoid arthritis. J Rheumatol 2002;29:1659-1664.
34. Baerwald C, Graefe C, von Wichert P, Krause A: Decreased density of β-adrenergic receptors on peripheral blood mononuclear cells in patients with rheumatoid arthritis. J Rheumatol 1992;19:204-210.
35. 1-adrenergic receptors on leukocytes of patients with polyarticular juvenile rheumatoid arthritis. J Neuroimmunol 1996;71:223-226.
36. Miller LE, Justen HP, Scholmerich J, Straub RH: The loss of sympathetic nerve fibers in the synovial tissue of patients with rheumatoid arthritis is accompanied by increased norepinephrine release from synovial macrophages. FASEB J 2000;14:2097-2107.
37. Zautra AJ, Hoffman J, Potter P, Matt KS, Yocum D, Castro L: Examination of changes in interpersonal stress as a factor in disease exacerbations among women with rheumatoid arthritis. Ann Behav Med 1997;19:279-286.
38. 1-adrenergic receptors. J Neuroimmunol 2000;110: 8-12.
39. Kittner JM, Jacobs R, Pawlak CR, Heijnen CJ, Schedlowsy M, Schmidt RE: Adrenaline-induced immunological changes are altered in patients with rheumatoid arthritis. Rheumatology (Oxford) 2002;41:1031-1039.
40. Marcenaro M, Prete C, Badini A, Sulli A, Magi E, Cutolo M: Rheumatoid arthritis, personality, stress response style, and coping with illness: a preliminary survey. Ann NY Acad Sci 1999;876:419-425.
41. Cutolo M, Villaggio B, Foppiani L, Briata M, Sulli A, Pizzorni C, Faelli F, Prete C, Felli L, Seriolo B, Giusti M: The hypothalamic-pituitary-adrenal and gonadal axes in rheumatoid arthritis. Ann NY Acad Sci 2000;917:835-843.
42. Cutolo M, Sulli A, Pizzorni C, Secchi ME, Soldano S, Seriolo B, Straub RH, Otsa K, Maestroni GJ: Circadian rhythms: glucocorticoids and arthritis. Ann NY Acad Sci 2006;1069:289-299.