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Volumn 322, Issue 3, 2007, Pages 1228-1236

Development of gallium compounds for treatment of lymphoma: Gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CASPASE 3; GALLIUM MALTOLATE; GALLIUM NITRATE; HYDROXYPYRONE GALLIUM; MITOQUINONE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 42; MONOCLONAL ANTIBODY 6; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 34548075249     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.126342     Document Type: Article
Times cited : (100)

References (40)
  • 1
    • 31544447745 scopus 로고    scopus 로고
    • Complexes of cytotoxic chelators from the dipyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues
    • Bernhardt PV, Mattsson J, and Richardson DR (2006) Complexes of cytotoxic chelators from the dipyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues. Inorg Chem 45:752-760.
    • (2006) Inorg Chem , vol.45 , pp. 752-760
    • Bernhardt, P.V.1    Mattsson, J.2    Richardson, D.R.3
  • 2
    • 0034101581 scopus 로고    scopus 로고
    • Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability
    • Bernstein LR, Tanner T, Godfrey C, and Noll B (2000) Chemistry and pharmacokinetics of gallium maltolate, a compound with high oral gallium bioavailability. Metal Based Drugs 7:33-47.
    • (2000) Metal Based Drugs , vol.7 , pp. 33-47
    • Bernstein, L.R.1    Tanner, T.2    Godfrey, C.3    Noll, B.4
  • 3
    • 2642519499 scopus 로고    scopus 로고
    • Gallium nitrate for the treatment of non-Hodgkin's lymphoma
    • Chitambar CR (2004) Gallium nitrate for the treatment of non-Hodgkin's lymphoma. Expert Opin Invest Drugs 13:531-541.
    • (2004) Expert Opin Invest Drugs , vol.13 , pp. 531-541
    • Chitambar, C.R.1
  • 4
    • 0029950210 scopus 로고    scopus 로고
    • Evaluation of transferrin and gallium-pyridoxal isonicotinoyl hydrazone as potential therapeutic agents to overcome lymphoid leukemic cell resistance to gallium nitrate
    • Chitambar CR, Boon P, and Wereley JP (1996) Evaluation of transferrin and gallium-pyridoxal isonicotinoyl hydrazone as potential therapeutic agents to overcome lymphoid leukemic cell resistance to gallium nitrate. Clin Cancer Res 2:1009-1015.
    • (1996) Clin Cancer Res , vol.2 , pp. 1009-1015
    • Chitambar, C.R.1    Boon, P.2    Wereley, J.P.3
  • 5
    • 0024209928 scopus 로고
    • Inhibition of leukemic HL60 cell growth by transferrin-gallium: Effects on ribonucleotide reductase and demonstration of drug synergy with hydroxyurea
    • Chitambar CR, Matthaeus WG, Antholine WE, Graff K, and O'Brien WJ (1988) Inhibition of leukemic HL60 cell growth by transferrin-gallium: effects on ribonucleotide reductase and demonstration of drug synergy with hydroxyurea. Blood 72:1930-1936.
    • (1988) Blood , vol.72 , pp. 1930-1936
    • Chitambar, C.R.1    Matthaeus, W.G.2    Antholine, W.E.3    Graff, K.4    O'Brien, W.J.5
  • 6
    • 0026356901 scopus 로고
    • Inhibition of ribonucleotide reductase by gallium in murine leukemic L1210 cells
    • Chitambar CR, Narasimhan J, Guy J, Sem DS, and O'Brien WJ (1991) Inhibition of ribonucleotide reductase by gallium in murine leukemic L1210 cells. Cancer Res 51:6199-6201.
    • (1991) Cancer Res , vol.51 , pp. 6199-6201
    • Chitambar, C.R.1    Narasimhan, J.2    Guy, J.3    Sem, D.S.4    O'Brien, W.J.5
  • 7
    • 0022839492 scopus 로고
    • Effects of different transferrin forms on transferrin receptor expression, iron uptake and cellular proliferation of human leukemic HL60 cells: Mechanisms responsible for the specific cytotoxicity of transferrin-gallium
    • Chitambar CR and Seligman PA (1986) Effects of different transferrin forms on transferrin receptor expression, iron uptake and cellular proliferation of human leukemic HL60 cells: mechanisms responsible for the specific cytotoxicity of transferrin-gallium. J Clin Invest 78:1538-1546.
    • (1986) J Clin Invest , vol.78 , pp. 1538-1546
    • Chitambar, C.R.1    Seligman, P.A.2
  • 8
    • 0030999608 scopus 로고    scopus 로고
    • Resistance to the antitumor agent gallium nitrate in human leukemic cells is associated with decreased gallium/iron uptake, increased activity of iron regulatory protein-1, and decreased ferritin production
    • Chitambar CR and Wereley JP (1997) Resistance to the antitumor agent gallium nitrate in human leukemic cells is associated with decreased gallium/iron uptake, increased activity of iron regulatory protein-1, and decreased ferritin production. J Biol Chem 272:12151-12157.
    • (1997) J Biol Chem , vol.272 , pp. 12151-12157
    • Chitambar, C.R.1    Wereley, J.P.2
  • 9
    • 0031811699 scopus 로고    scopus 로고
    • Transferrin receptor-dependent and -independent iron transport in gallium-resistant human lymphoid leukemic cells
    • Chitambar CR and Wereley JP (1998) Transferrin receptor-dependent and -independent iron transport in gallium-resistant human lymphoid leukemic cells. Blood 91:4686-4693.
    • (1998) Blood , vol.91 , pp. 4686-4693
    • Chitambar, C.R.1    Wereley, J.P.2
  • 10
    • 33845208145 scopus 로고    scopus 로고
    • Gallium-induced cell death in lymphoma: Role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition
    • Chitambar CR, Wereley JP, and Matsuyama S (2006) Gallium-induced cell death in lymphoma: role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition. Mol Cancer Ther 5:2834-2843.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2834-2843
    • Chitambar, C.R.1    Wereley, J.P.2    Matsuyama, S.3
  • 11
    • 0030947983 scopus 로고    scopus 로고
    • Evaluation of continuous-infusion gallium nitrate and hydroxyurea in combination for the treatment of refractory non-Hodgkin's lymphoma
    • Chitambar CR, Zahir SA, Ritch PS, and Anderson T (1997) Evaluation of continuous-infusion gallium nitrate and hydroxyurea in combination for the treatment of refractory non-Hodgkin's lymphoma. Am J Clin Oncol 20:173-178.
    • (1997) Am J Clin Oncol , vol.20 , pp. 173-178
    • Chitambar, C.R.1    Zahir, S.A.2    Ritch, P.S.3    Anderson, T.4
  • 12
    • 0023262160 scopus 로고
    • Uptake of gallium-67 by human leukemic cells: Demonstration of transferrin receptor-dependent and transferrin- independent mechanisms
    • Chitambar CR and Zivkovic Z (1987) Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin- independent mechanisms. Cancer Res 47:3929-3934.
    • (1987) Cancer Res , vol.47 , pp. 3929-3934
    • Chitambar, C.R.1    Zivkovic, Z.2
  • 13
    • 33745591658 scopus 로고    scopus 로고
    • Gallium maltolate is a promising chemotherapeutic agent for the treatment of hepatocellular carcinoma
    • Chua MS, Bernstein LR, Li R, and So SK (2006) Gallium maltolate is a promising chemotherapeutic agent for the treatment of hepatocellular carcinoma. Anticancer Res 26:1739-1743.
    • (2006) Anticancer Res , vol.26 , pp. 1739-1743
    • Chua, M.S.1    Bernstein, L.R.2    Li, R.3    So, S.K.4
  • 15
    • 33645116062 scopus 로고    scopus 로고
    • Resistance to the antineoplastic agent gallium nitrate results in marked alterations in intracellular iron and gallium trafficking: Identification of novel intermediates
    • Davies NP, Rahmanto YS, Chitambar CR, and Richardson DR (2006) Resistance to the antineoplastic agent gallium nitrate results in marked alterations in intracellular iron and gallium trafficking: identification of novel intermediates. J Pharmacol Exp Ther 317:153-162.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 153-162
    • Davies, N.P.1    Rahmanto, Y.S.2    Chitambar, C.R.3    Richardson, D.R.4
  • 16
    • 4444315545 scopus 로고    scopus 로고
    • Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis
    • Dhanasekaran A, Kotamraju S, Kalivendi SV, Matsunaga T, Shang T, Keszler A, Joseph J, and Kalyanaraman B (2004) Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. J Biol Chem 279:37575- 37587.
    • (2004) J Biol Chem , vol.279 , pp. 37575-37587
    • Dhanasekaran, A.1    Kotamraju, S.2    Kalivendi, S.V.3    Matsunaga, T.4    Shang, T.5    Keszler, A.6    Joseph, J.7    Kalyanaraman, B.8
  • 17
    • 0038486137 scopus 로고    scopus 로고
    • Gallium nitrate in the treatment of bladder cancer
    • Einhorn L (2003) Gallium nitrate in the treatment of bladder cancer. Semin Oncol 30:34-41.
    • (2003) Semin Oncol , vol.30 , pp. 34-41
    • Einhorn, L.1
  • 18
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • Green DR and Kroemer G (2004) The pathophysiology of mitochondrial cell death. Science 305:626-629.
    • (2004) Science , vol.305 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 19
    • 0021107162 scopus 로고
    • Thermodynamic binding constants for gallium transferrin
    • Harris WR and Pecoraro VL (1983) Thermodynamic binding constants for gallium transferrin. Biochemistry 22:292-299.
    • (1983) Biochemistry , vol.22 , pp. 292-299
    • Harris, W.R.1    Pecoraro, V.L.2
  • 21
    • 0022547119 scopus 로고
    • Phase II evaluation of bolus gallium nitrate in lymphoproliferative disorders: A Southeastern Cancer Study Group trial
    • Keller J, Bartolucci A, Carpenter JT Jr, and Feagler J (1986) Phase II evaluation of bolus gallium nitrate in lymphoproliferative disorders: a Southeastern Cancer Study Group trial. Cancer Treat Rep 70:1221-1223.
    • (1986) Cancer Treat Rep , vol.70 , pp. 1221-1223
    • Keller, J.1    Bartolucci, A.2    Carpenter Jr, J.T.3    Feagler, J.4
  • 24
    • 0028990145 scopus 로고
    • Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status
    • Little JB, Nagasawa H, Keng PC, Yu Y, and Li CY (1995) Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status. J Biol Chem 270:11033-11036.
    • (1995) J Biol Chem , vol.270 , pp. 11033-11036
    • Little, J.B.1    Nagasawa, H.2    Keng, P.C.3    Yu, Y.4    Li, C.Y.5
  • 25
    • 0030210778 scopus 로고    scopus 로고
    • The hydroxyl radical: From chemistry to human disease
    • Lubec G (1996) The hydroxyl radical: From chemistry to human disease. J Invest Med 44:324-346.
    • (1996) J Invest Med , vol.44 , pp. 324-346
    • Lubec, G.1
  • 26
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immmunol Methods 65:55-63.
    • (1983) J Immmunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 27
    • 33845208272 scopus 로고    scopus 로고
    • Phase 2 multicenter trial of gallium nitrate in patients with advanced non-Hodgkin's lymphoma (NHL)
    • Pro B, Bociek RG, Chitambar CR, Gregory SA, Leonard JP, Smith S, and Novick S (2004) Phase 2 multicenter trial of gallium nitrate in patients with advanced non-Hodgkin's lymphoma (NHL). Blood 104:682A.
    • (2004) Blood , vol.104
    • Pro, B.1    Bociek, R.G.2    Chitambar, C.R.3    Gregory, S.A.4    Leonard, J.P.5    Smith, S.6    Novick, S.7
  • 28
    • 0034306267 scopus 로고    scopus 로고
    • Mitochondria, oxygen free radicals, disease and ageing
    • Raha S and Robinson BH (2000) Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem Sci 25:502-508.
    • (2000) Trends Biochem Sci , vol.25 , pp. 502-508
    • Raha, S.1    Robinson, B.H.2
  • 29
    • 0019949142 scopus 로고
    • Tumor cell toxicity of stable gallium nitrate: Enhancement by transferrin and protection by iron
    • Rasey JS, Nelson NJ, and Larson SM (1982) Tumor cell toxicity of stable gallium nitrate: enhancement by transferrin and protection by iron. Eur J Cancer Clin Oncol l8:66l-668.
    • (1982) Eur J Cancer Clin Oncol l8:66l-668
    • Rasey, J.S.1    Nelson, N.J.2    Larson, S.M.3
  • 30
    • 0028891974 scopus 로고
    • The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents
    • Richardson DR, Tran EH, and Ponka P (1995) The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents. Blood 86:4295-4306.
    • (1995) Blood , vol.86 , pp. 4295-4306
    • Richardson, D.R.1    Tran, E.H.2    Ponka, P.3
  • 31
    • 0034659123 scopus 로고    scopus 로고
    • Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1
    • Said Ahmed M, Hung WY, Zu JS, Hockberger P, and Siddique T (2000) Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1. J Neurol Sci 176:88-94.
    • (2000) J Neurol Sci , vol.176 , pp. 88-94
    • Said Ahmed, M.1    Hung, W.Y.2    Zu, J.S.3    Hockberger, P.4    Siddique, T.5
  • 32
    • 0022616986 scopus 로고
    • Mechanisms of growth inhibition by anti-transferrin receptor monoclonal antibodies
    • Taetle R, Castognola J, and Mendelsohn J (1986) Mechanisms of growth inhibition by anti-transferrin receptor monoclonal antibodies. Cancer Res 46:1759-1763.
    • (1986) Cancer Res , vol.46 , pp. 1759-1763
    • Taetle, R.1    Castognola, J.2    Mendelsohn, J.3
  • 33
    • 33744509651 scopus 로고    scopus 로고
    • Metal complexes of maltol and close analogues in medicinal inorganic chemistry
    • Thompson KH, Barta CA, and Orvig C (2006) Metal complexes of maltol and close analogues in medicinal inorganic chemistry. Chem Soc Rev 35:545-556.
    • (2006) Chem Soc Rev , vol.35 , pp. 545-556
    • Thompson, K.H.1    Barta, C.A.2    Orvig, C.3
  • 34
    • 0000302649 scopus 로고
    • Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro
    • Trowbridge IS and Lopez F (1982) Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. Proc Natl Acad Sci U S A 79:1175-1179.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 1175-1179
    • Trowbridge, I.S.1    Lopez, F.2
  • 36
    • 0020561470 scopus 로고
    • Treatment of patients with advanced malignant lymphoma using gallium nitrate administered as a seven-day continuous infusion
    • Warrell RP, Jr., Coonley CJ, Straus DJ, and Young CW (1983) Treatment of patients with advanced malignant lymphoma using gallium nitrate administered as a seven-day continuous infusion. Cancer 51:1982-1987.
    • (1983) Cancer , vol.51 , pp. 1982-1987
    • Warrell Jr., R.P.1    Coonley, C.J.2    Straus, D.J.3    Young, C.W.4
  • 37
    • 0020592438 scopus 로고
    • Gallium nitrate in malignant lymphoma: A Southwest Oncology Group study
    • Weick JK, Stephens RL, Baker LH, and Jones SE (1983) Gallium nitrate in malignant lymphoma: a Southwest Oncology Group study. Cancer Treat Rep 67:823-825.
    • (1983) Cancer Treat Rep , vol.67 , pp. 823-825
    • Weick, J.K.1    Stephens, R.L.2    Baker, L.H.3    Jones, S.E.4
  • 38
    • 0028944890 scopus 로고
    • Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines
    • Xia F, Wang X, Wang YH, Tsang NM, Yandell DW, Kelsey KT, and Liber HL (1995) Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines. Cancer Res 55:12-15.
    • (1995) Cancer Res , vol.55 , pp. 12-15
    • Xia, F.1    Wang, X.2    Wang, Y.H.3    Tsang, N.M.4    Yandell, D.W.5    Kelsey, K.T.6    Liber, H.L.7
  • 39
    • 33847409311 scopus 로고    scopus 로고
    • Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate
    • Yang M, Kroft SH, and Chitambar CR (2007) Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate. Mol Cancer Ther 6:633-643.
    • (2007) Mol Cancer Ther , vol.6 , pp. 633-643
    • Yang, M.1    Kroft, S.H.2    Chitambar, C.R.3


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