Charges in the cytoplasmic pore control intrinsic inward rectification and single-channel properties in Kir1.1 and Kir2.1 channels

Journal of Membrane Biology

Volumn 215, Issue 2-3, 2007, Pages 181-193

  Chang, Hsueh Kai ^a   Yeh, Shih Hao ^a   Shieh, Ru Chi ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

Chimera; Electrostatic potential; Intrinsic inward rectification; Kir channel; Open channel fluctuation; Single channel conductance

Indexed keywords

GLYCINE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; MUTANT PROTEIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL KIR2.1; POTASSIUM ION; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CYTOPLASM; DEPOLARIZATION; ELECTRIC POTENTIAL; ELECTRICITY; GENE MUTATION; MEMBRANE CONDUCTANCE; MOLECULAR INTERACTION; NONHUMAN; PATCH CLAMP; POROSITY;

AMINO ACID SUBSTITUTION; ANIMALS; ELECTRIC CONDUCTIVITY; FEMALE; MEMBRANE POTENTIALS; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN STRUCTURE, SECONDARY; XENOPUS;

EID: 34548049980     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-007-9017-0     Document Type: Article

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