Upregulation of sodium-dependent vitamin C transporter 2 expression in adrenals increases norepinephrine production and aggravates hyperlipidemia in mice with streptozotocin-induced diabetes

Biochemical Pharmacology

Volumn 74, Issue 7, 2007, Pages 1020-1028

  Wu, Ximei ^a   Iguchi, Takuma ^a   Hirano, Junko ^a   Fujita, Isami ^a   Ueda, Hidenori ^a   Itoh, Norio ^a   Tanaka, Keiichi ^a,b   Nakanishi, Tsuyoshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA OHTANI UNIVERSITY   (Japan)

Author keywords

Adrenal; Ascorbic acid; Diabetes; Hyperlipidemia; Norepinephrine; Sodium dependent vitamin C transporter (SVCT)

Indexed keywords

ASCORBIC ACID; CARRIER PROTEIN; FATTY ACID; SODIUM DEPENDENT VITAMIN C TRANSPORTER 2; STREPTOZOCIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE EXACERBATION; DRUG ACCUMULATION; DRUG UPTAKE; FATTY ACID BLOOD LEVEL; HYPERLIPIDEMIA; MALE; MOUSE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES; SUPPLEMENTATION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; VITAMIN BLOOD LEVEL;

ADRENAL GLANDS; ANIMALS; ASCORBIC ACID; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HYPERLIPIDEMIAS; KIDNEY; MICE; MICE, INBRED ICR; NOREPINEPHRINE; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; RNA, MESSENGER; STREPTOZOCIN; SYMPORTERS; UP-REGULATION;

EID: 34548036070     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.05.024     Document Type: Article

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