The role of the endothelin axis and microvessel density in bladder cancer - Correlation with tumor angiogenesis and clinical prognosis

Oncology Reports

Volumn 18, Issue 1, 2007, Pages 133-138

  Herrmann, Edwin ^a   Bögemann, Martin ^a   Bierer, Stefan ^a   Eltze, Elke ^a   Toma, Marieta I ^b   Köpke, Thomas ^a   Hertle, Lothar ^a   Wülfing, Christian ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Angiogenesis; Endothelin axis; Endothelin receptor; Endothelin A; Endothelin B; Microvessel density

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; TUMOR MARKER;

ADULT; AGED; ARTICLE; BLADDER TUMOR; CANCER STAGING; CYSTECTOMY; ENZYME IMMUNOASSAY; FEMALE; HUMAN; LYMPH NODE; MALE; METABOLISM; METASTASIS; MIDDLE AGED; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TRANSITIONAL CELL CARCINOMA; VASCULARIZATION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CARCINOMA, TRANSITIONAL CELL; CYSTECTOMY; ENDOTHELIN-1; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPH NODES; MALE; MIDDLE AGED; NEOPLASM STAGING; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; URINARY BLADDER NEOPLASMS;

EID: 34548026298     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.18.1.133     Document Type: Article

References (23)

1. Weidner N, Semple JP, Welch WR and Folkman J: Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324: 1-8, 1991.
2. Bochner BH, Cote RJ, Weidner N, et al: Angiogenesis in bladder cancer: relationship between microvessel density and tumor prognosis. J Natl Cancer Inst 87: 1603-1612, 1995.
3. Philp EA, Stephenson TJ and Reed MW: Prognostic significance of angiogenesis in transitional cell carcinoma of the human urinary bladder. Br J Urol 77: 352-357, 1996. (Pubitemid 26090968)
4. Inoue K, Slaton JW, Karashima T, et al: The prognostic value of angiogenesis factor expression for predicting recurrence and metastasis of bladder cancer after neoadjuvant chemotherapy and radical cystectomy. Clin Cancer Res 6: 4866-4873, 2000. (Pubitemid 32110431)
5. Nelson J, Bagnato A, Battistini B and Nisen P: The endothelin axis: emerging role in cancer. Nat Rev Cancer 3: 110-116, 2003. (Pubitemid 37328878)
6. Herrmann E, Bogemann M, Bierer S, Eltze E, Hertle L and Wulfing C: The endothelin axis in urologic tumors: mechanisms of tumor biology and therapeutic implications. Exp Review Anticancer Ther 6: 73-81, 2006.
7. Spinella F, Rosano L, Di Castro V, Natali PG and Bagnato A: Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells. J Biol Chem 277: 27850-27855, 2002. (Pubitemid 34966730)
8. Wulfing P, Kersting C, Tio J, et al: Endothelin-1-, endothelin-A-, and endothelin-B-receptor expression is correlated with vascular endothelial growth factor expression and angiogenesis in breast cancer. Clin Cancer Res 10: 2393-2400, 2004. (Pubitemid 38445698)
9. Bek EL and McMillen MA: Endothelins are angiogenic. J Cardiovasc Pharmacol 36: 135-139, 2000.
10. Shankar A, Loizidou M, Aliev G, et al: Raised endothelin 1 levels in patients with colorectal liver metastases. Br J Surg 85: 502-506, 1998. (Pubitemid 28175443)
11. Wulfing C, Eltze E, Yamini J, et al: Expression of the endothelin axis in bladder cancer: relationship to clinicopathologic parameters and long-term survival. Eur Urol 47: 593-600, 2005. (Pubitemid 40521902)
12. Wulfing C, Eltze E, Piechota H, et al: Expression of endothelin-1 and endothelin-A and -B receptors in invasive bladder cancer. Oncol Rep 13: 223-228, 2005.
13. Wulfing P, Diallo R, Kersting C, et al: Expression of endothelin-1, endothelin-A, and endothelin-B receptor in human breast cancer and correlation with long-term follow-up. Clin Cancer Res 9: 4125-4131, 2003. (Pubitemid 37204029)
14. Friedrich MG, Toma MI, Petri S, et al: Expression of Maspin in non-muscle invasive bladder carcinoma: correlation with tumor angiogenesis and prognosis. Eur Urol 45: 737-743, 2004. (Pubitemid 38638393)
15. Nelson JB: Endothelin inhibition: novel therapy for prostate cancer. J Urol 170: 65-67, 2003.
16. Carducci MA, Padley RJ, Breul J, et al: Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial. J Clin Oncol 21: 679-689, 2003. (Pubitemid 46621903)
17. Salani D, Di Castro V, Nicotra MR, et al: Role of endothelin-1 in neovascularization of ovarian carcinoma. Am J Pathol 157: 1537-1547, 2000.
18. Stiles JD, Ostrow PT, Balos LL, et al: Correlation of endothelin-1 and transforming growth factor beta 1 with malignancy and vascularity in human gliomas. J Neuropathol Exp Neurol 56: 435-439, 1997. (Pubitemid 27465026)
19. Bartoletti R, Cai T, Nesi G, Sardi I and Rizzo M: Qualitative and quantitative analysis of angiogenetic factors in transitional cell bladder carcinoma: relationship with clinical course at 10 years follow-up. Oncol Rep 14: 251-255, 2005.
20. Offersen BV, Borre M and Overgaard J: Quantification of angiogenesis as a prognostic marker in human carcinomas: a critical evaluation of histopathological methods for estimation of vascular density. Eur Urol 39: 881-890, 2003. (Pubitemid 36428619)
21. Offersen BV, Knap MM, Marcussen N, Horsman MR, Hamilton-Dutoit S and Overgaard J: Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis. Br J Cancer 87: 1422-1430, 2002. (Pubitemid 36044318)
22. Mihatsch MJ, Rist M, Romppanen T and Rutishauser G: Prognostic significance of peritumoural inflammation in invasive urothelial bladder carcinoma. Urol Res 7: 97-102, 1979. (Pubitemid 9243845)
23. Flamm J: Tumor-associated tissue inflammatory reaction and eosinophilia in primary superficial bladder cancer. Urology 40: 180-185, 1992.