Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance

Obesity Reviews

Volumn 8, Issue 5, 2007, Pages 419-423

  Crimmins, N A ^a,b   Martin, L J ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Adiponectin receptor; ADIPOR1; ADIPOR2; Insulin resistance

Indexed keywords

ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2;

ARTICLE; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHENOTYPE; REPRODUCIBILITY;

ADIPONECTIN; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INSULIN RESISTANCE; POLYMORPHISM, GENETIC; RECEPTORS, CELL SURFACE;

EID: 34548020729     PISSN: 14677881     EISSN: 1467789X     Source Type: Journal    
DOI: 10.1111/j.1467-789X.2007.00348.x     Document Type: Article

References (16)

1. Berg A, Du Combs TX, Brownlee M, Scherer P. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001 7 : 947 953.
2. Combs T, Berg A, Obici S, Scherer P, Rossetti L. Endogenous glucose production is inhibited by the adipose-derived protein Acrp 30. J Clin Invest 2001 108 : 1875 1881.
3. Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno N, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003 423 : 762 768.
4. Civitarese A, Jenkinson C, Richardson D, Bajaj M, Cusi K, Kashyap S, Berria R, Belfort R, DeFronzo R, Mandarino L, Ravussin E. Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia 2004 47 : 816 820.
5. Kharroubi I, Rasschaert J, Eizirik D, Cnop M. Expression of adiponectin receptors in pancreatic beta cells. Biochem Biophys Res Commun 2003 312 : 1118 1122.
6. Purcell S, Cherny S, Sham P. Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinfomatics 2003 19 : 149 150.
7. Lenth R. Java Applets for Power and Sample Size. 2006 [WWW document]. URL http://www.stat.uiowa.edu/∼rlenth/Power (accessed 5 September 2006).
8. Wang H, Zhang H, Jia Y, Zhang Z, Craig R, Wang X, Elbein S. Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance. Diabetes 2004 53 : 2132 2136.
9. Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Kimura S, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002 51 : 536 540.
10. Damcott C, Ott S, Pollin T, Reinhart L, Wang J, O'Connell J, Mitchell B, Shuldiner A. Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish. Diabetes 2005 54 : 2245 2250.
11. Stefan N, Machicao F, Staiger H, Machann J, Schick F, Tschritter O, Spieth C, Weigert C, Fritsche A, Strumvoll M, Haring H. Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. Diabetologia 2005 48 : 2282 2291.
12. Kantartzis K, Fritsche A, Machicao F, Haring H, Stefan N. The -8503 g/a polymorphism of the adiponectin receptor 1 gene is associated with insulin sensitivity dependent on adiposity. Diabetes Care 2006 29 : 464.
13. Vaxillaire M, Dechaume A, Vasseur-Delannoy V, Lahmidi S, Vatin V, Lepretre F, Boutin P, Hercberg S, Charpentier G, Dina C, Froguel P. Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population. Diabetes 2006 55 : 856 861.
14. Freedman M, Reich D, Penney K, McDonald G, Mignault A, Patterson N, Gabriel S, Topol E, Smoller J, Pato C, Pato M, Petryshen T, Kolonel L, Lander E, Sklar P, Henderson B, Hirschhorn J, Altshuler D. Assessing the impact of population stratification on genetic association studies. Nat Genet 2004 36 : 388 393.
15. Marchini J, Cardon L, Phillips M, Donnelly P. The effects of human population structure on large genetic association studies. Nat Genet 2004 36 : 512 517.
16. Staiger H, Kaltenbach S, Staiger K, Stefan N, Fritsche A, Guirguis A, Peterfi C, Weisser M, Machicao FSM, Haring H. Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism. Diabetes 2004 53 : 2195 2201.