Preparation of two-drug composite microparticles to improve the dissolution of insoluble drug in water for use with a 4-fluid nozzle spray drier

Journal of Controlled Release

Volumn 107, Issue 3, 2005, Pages 387-394

  Ozeki, Tetsuya ^a   Beppu, Shuji ^a   Mizoe, Takuto ^a   Takashima, Yuuki ^a   Yuasa, Hiroshi ^a   Okada, Hiroaki ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ANALYSIS; CRYSTALLIZATION; DISSOLUTION;

FLURBIPROFEN (FP); MICROPARTICLES; NOZZLE SPRAY DRIERS; SODIUM SALICYLATE (SS);

DRUG PRODUCTS;

ALCOHOL; FLURBIPROFEN; FLURBIPROFEN PLUS SALICYLATE SODIUM; SALICYLATE SODIUM; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; COMPOSITE MATERIAL; CRYSTALLIZATION; DEVICE; DISSOLUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SYNTHESIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPRAY DRYING; TECHNIQUE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHYSICAL; DESICCATION; ETHANOL; FLURBIPROFEN; MICROSCOPY, ELECTRON, SCANNING; NANOSTRUCTURES; PARTICLE SIZE; SODIUM SALICYLATE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WATER; X-RAY DIFFRACTION;

EID: 25844477518     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.06.012     Document Type: Article

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