Structure-interaction relationships between the bile acid GCA and pharmaceuticals using multivariate data analysis and capillary electrophoresis

Journal of Pharmaceutical Sciences

Volumn 96, Issue 8, 2007, Pages 2057-2073

  Stålberg, Olle ^a   Kruusmägi, Martin ^b   Svensson, Mats A ^a   Norinder, U ^a   Pettersson, Curt ^b  

^a ASTRAZENECA R AND D   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Analytical chemistry; Bile acid transporters; Electrophoresis; Multivariate analysis; Structure property relationship (SPR)

Indexed keywords

ATENOLOL; AZATHIOPRINE; BAMBUTEROL; BILE ACID; BUDESONIDE; BUSPIRONE; CHLORTALIDONE; CLENBUTEROL; GLYCOCHOLIC ACID; HYDROCORTISONE; LAMOTRIGINE; LEFLUNOMIDE; LETROZOLE; MELAGATRAN; MOLINDONE; NOREPHEDRINE; NORTRIPTYLINE; PIROXICAM; PROPRANOLOL DERIVATIVE; QUININE; SALBUTAMOL; SILDENAFIL; SOTALOL; SULFINPYRAZONE; TERBUTALINE; TETRACYCLINE; THIORIDAZINE; TIZANIDINE; TOLBUTAMIDE; UNINDEXED DRUG;

ARTICLE; CAPILLARY ELECTROPHORESIS; DRUG DETERMINATION; DRUG SOLUBILITY; ELECTROPHORETIC MOBILITY; HYDROPHOBICITY; IN VIVO STUDY; MATHEMATICAL MODEL; PARTIAL LEAST SQUARES REGRESSION; PH; PKA; STRUCTURE ACTIVITY RELATION;

EID: 34548011907     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20852     Document Type: Article

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