Extracellular ATP and its effects on physiological and pathological mineralization

Current Opinion in Orthopaedics

Volumn 18, Issue 5, 2007, Pages 460-466

  Thouverey, Cyril ^a,b,c   Bleicher, Françoise ^c,d   Bandorowicz Pikula, Joanna ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSITÉ LYON 1   (France)

^d Univ Lyon 1   (France)

Author keywords

ATP; Bone mineralization; Hypertrophic chondrocytes; Matrix vesicles; Osteoblasts

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; CALCIUM PHOSPHATE; HYDROXYAPATITE; INORGANIC PYROPHOSPHATASE; NUCLEOTIDE TRIPHOSPHATE PYROPHOSPHATASE; PURINE; PYRIMIDINE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

BONE CELL; BONE GROWTH; BONE MATRIX; BONE METABOLISM; BONE MINERALIZATION; CARTILAGE CELL; HUMAN; HYPERTROPHY; NONHUMAN; OSTEOBLAST; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN PROCESSING; REVIEW;

EID: 34547906432     PISSN: 10419918     EISSN: None     Source Type: Journal    
DOI: 10.1097/BCO.0b013e328285dfe8     Document Type: Review

References (62)

1. Kirsch T. Determinants of pathological mineralization. Curr Opin Rheumatol 2006; 18:174-180. An excellent review on how inhibitors and effectors can regulate physiological and pathological mineralization.
2. Qi J, Chi L, Faber J, et al. ATP reduces gel compaction in osteoblastpopulated collagen gels. J Appl Physiol 2007; 102:1152-1160.
3. Turner CH. Bone strength: current concepts. Ann N Y Acad Sci 2006; 1068:429-446.
4. Hoebertz A, Arnett TR, Burnstock G. Regulation of bone resorption and formation by purines and pyrimidines. Trends Pharmacol Sci 2003; 24:290-297.
5. Garimella R, Bi X, Anderson HC, Camacho NP. Nature of phosphate substrate as a major determinant of mineral type formed in matrix vesicle-mediated in vitro mineralization: an FTIR imaging study. Bone 2006; 38:811-817. Experimental paper reporting on the balance between apatite mineral and immature mineral, affected by the nature of phosphoester substrates (AMP, ATP, etc.) hydrolyzed by matrix vesicle enzymes.
6. Franke H, Krügel U, Illes P. P2 receptors and neuronal injury. Pflügers Arch 2006; 452:622-644.
7. Romanello M, Codognotto A, Bicego M, et al. Autocrine/paracrine stimulation of purinergic receptors in osteoblasts: contribution of vesicular ATP release. Biochem Biophys Res Commun 2005; 331:1429-1438.
8. Graff RD, Picher M, Lee GM. Extracellular nucleotides, cartilage stress, and calcium crystal formation. Curr Opin Rheumatol 2003; 15:315-320.
9. Harada S, Rodan GA. Control of osteoblast function and regulation of bone mass. Nature 2003; 423:349-355.
10. 4 could function as an 'off switch' for mineralized bone formation.
11. Burnstock G. Purinergic signaling - an overview. Novartis Found Symp 2006; 276:26-48.
12. Khakh BS, North RA. P2X receptors as cell-surface ATP sensors in health and disease. Nature 2006; 442:527-532.
13. Katz S, Boland R, Santillan G. Modulation of ERK 1/2 and p38 MAPK signaling pathways by ATP in osteoblasts: involvement of mechanical stress-activated calcium influx, PKC and Src activation. Int J Biochem Cell Biol 2006; 38:2082-2091.
14. Hiken JF, Steinberg TH. ATP downregulates P2X7 and inhibits osteoclast formation in RAW cells. Am J Physiol Cell Physiol 2004; 287:C403-C412.
15. Korcok J, Raimundo LN, Du X, et al. P2Y6 nucleotide receptors activate NF-κB and increase survival of osteoclasts. J Biol Chem 2005; 280:16909-16915.
16. Bonewald LF. Mechanosensation and transduction in osteocytes. Bonekey Osteovision 2006; 3:7-15.
17. Panupinthu N, Zhao L, Possmayer F, et al. P2X7 nucleotide receptors mediate blebbing in osteoblasts through a pathway involving lysophosphatidic acid. J Biol Chem 2007; 282:3403-3412. Experimental paper describing the link between P2X7 receptors and a phospholipase producing lysophosphatidic acid.
18. q signaling in osteoblasts. J Biol Chem 2006; 281:32684-32693.
19. 2+ permeability and flux in two members of the ATP-gated P2X receptor family. J Gen Physiol 2007; 129:245-256.
20. Coppi E, Pugliese AM, Urbani S, et al. ATP modulates cell proliferation and elicits two different electrophysiological responses in human mesenchymal stem cells. Stem Cells 2007; [Epub ahead of print].
21. Plotkin LI, Manolagas SC, Bellido T. Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their antiapoptotic effects on osteoblasts/osteocytes with novel analogs. Bone 2006; 39:443-452.
22. Yoon MJ, Lee HJ, Lee YS, et al. Extracellular ATP is involved in the induction of apoptosis in murine hematopoietic cells. Biol Pharm Bull 2007; 30:671-676.
23. Riddle RC, Taylor AF, Rogers JR, Donahue HJ. ATP release mediates fluid flow-induced proliferation of human bone marrow stromal cells. J Bone Miner Res 2007; 22:589-600. This article describes ATP-induced human osteoprogenitor cell proliferation and differentiation.
24. Rossi L, Manfredi R, Bertolini F, et al. The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration. Blood 2007; 109:533-542.
25. Henriksen Z, Hiken JF, Steiberg TH, Jorgensen NR. The predominant mechanism of intercellular calcium wave propagation changes during long-term culture of human osteoblast-like cells. Cell Calcium 2006; 39:435-444. The authors reported on P2Y receptor-mediated and gap junction-mediated intercellular calcium signaling.
26. Evans BAJ, Elford C, Pexa A, et al. Human osteoblast precursors produce extracellular adenosine, which modulates their secretion of IL-6 and osteoprotegerin. J Bone Miner Res 2006; 21:228-236. The authors concluded that extracellular adenosine is a regulator of human bone marrow stromal cell differentiation.
27. Miyazaki T, Tanaka S, Sanjay A, Baron R. The role of c-Src kinase in the regulation of osteoclast function. Mod Rheumatol 2006; 16:68-74.
28. Morimoto R, Uehara S, Yatsushiro S, et al. Secretion of L-glutamate from osteoclasts through transcytosis. EMBO J 2006; 25:4175-4186.
29. +-ATPase in osteoclasts. Biochem Biophys Res Commun 2007; in press.
30. Dalgarno D, Stehle T, Narula S, et al. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds. Chem Biol Drug Des 2006; 67:46-57.
31. Fitzgerald JB, Jin M, Dean D, et al. Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP. J Biol Chem 2004; 279:19502-19511.
32. Kono T, Nishikori T, Kataoka H, et al. Spontaneous oscillation and mechanically induced calcium waves in chondrocytes. Cell Biochem Funct 2006; 24:103-111.
33. Millward-Sadler SJ, Wright MO, Flatman PW, Salter DM. ATP in the mechanotransduction pathway of normal human chondrocytes. Biorheology 2004; 41:567-575.
34. 2 tension on pH homeostasis in equine articular chondrocytes. Arthritis Rheum 2006; 54:3523-3532.
35. Mouw JK, Imler SM, Levenston ME. Ion-channel regulation of chondrocyte matrix synthesis in 3D culture under static and dynamic compression. Biomech Model Mechanobiol 2007; 6:33-41.
36. ATP) potassium channels in human and equine articular chondrocytes. Osteoarthritis Cartilage 2007; 15:1-8.
37. Balcerzak M, Radisson J, Azzar G, et al. A comparative analysis of strategies for isolation of matrix vesicles. Anal Biochem 2007; 361:176-182.
38. 2+ and phosphate deposition in isolated chicken matrix vesicles. J Biol Chem 2005; 280:37289-37296.
39. i for mineral deposition.
40. Rey A, Manen D, Rizzoli R, et al. Evidences for a role of p38 MAP kinase in the stimulation of alkaline phosphatase and matrix mineralization induced by parathyroid hormone in osteoblastic cells. Bone 2007; 41:59-67.
41. 2D3-regulated matrix vesicle molecular mechanisms involved in extracellular matrix turnover.
42. Balcerzak M, Pikula S, Buchet R. Phosphorylation-dependent phospholipase D activity of matrix vesicles. FEBS Lett 2006; 580:5676-5680.
43. 2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltagedependent anion-selective channel (VDAC). J Biol Chem 2006; 281:17347-17358.
44. Shoshan-Barmatz V, Israelson A, Brdiczka D, Sheu SS. The voltage-dependent anion channel (VDAC): function in intracellular signaling, cell life and cell death. Curr Pharm Des 2006; 12:2249-2270.
45. Xiao Z, Camalier CE, Nagashima K, et al. Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts. J Cell Physiol 2007;210:325-335. The first extracellular matrix vesicle proteome analysis.
46. 2D3 regulates chondrocyte matrix vesicle protein kinase C (PKC) directly via G-protein-dependent mechanisms and indirectly via incorporation of PKC during matrix vesicle biogenesis. J Biol Chem 2002; 277:11828-11837.
47. Rosenthal AK, Gohr CM, Uzuki M, Masuda I. Osteopontin promotes pathologic mineralization in articular cartilage. Matrix Biol 2007; 26:96-105.
48. Viriyavejkul P, Wilairatana V, Tanavalee A, Jaovisidha K. Comparison of characteristics of patients with and without calcium pyrophosphate dihydrate crystal deposition disease who underwent total knee replacement surgery for osteoarthritis. Osteoarthritis Cartilage 2007; 15:232-235.
49. Gerster JC, Varisce PA, Kern J, et al. CPPD crystal deposition disease in patients with rheumatoid arthritis. Clin Rheumatol 2006; 25:468-469.
50. Rothschild B. CPPD complicating other forms of inflammatory arthritis. Clin Rheumatol 2007; 26:1130-1131.
51. Reginato AM, Olsen BR. Genetics and experimental models of crystalinduced arthritis. Lessons learned from mice and men: is it crystal clear? Curr Opin Rheumatol 2007; 19:134-145.
52. Martinon F, Pétrilli V, Mayor A, et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440:237-241.
53. Johnson K, Hashimoto S, Lotz M, et al. Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification. Arthritis Rheum 2001; 44:1071-1081.
54. Osman L, Chester AH, Amrani M, et al. A novel role of extracellular nucleotides in valve calcification: a potential target for atorvastatin. Circulation 2006; 114 (1 Suppl):1566-1572.
55. Klement JF, Matsuzaki Y, Jiang Q-J, et al. Targeted ablation of the Abcc6 gene results in ectopic mineralization of connective tissues. Mol Cell Biol 2005; 25:8299-8310.
56. Meng H, Vera I, Che N, et al. Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through interactive genomics. Proc Natl Acad Sci U S A 2007; 104:4530-4535. The authors identified Abcc6 as the main gene causing dystrophic cardiac calcification and suggested potential pathways for gene action.
57. Baumgartner-Sigl S, Haberlandt E, Mumm S, et al. Pyridoxine-responsive seizures as the first symptom of infantile hypophosphatasia caused by two novel missense mutations (c.677T>C, p.M226T; c.1112C>T, p.T371I) of the tissue-nonspecific alkaline phosphatase gene. Bone 2007; 40:1655-1661.
58. Anderson HC, Harmey D, Camacho NP, et al. Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice. Am J Pathol 2005; 166:1711-1720.
59. -/- mice. J Bone Miner Res 2006; 21:1377-1386.
60. Reaven E, Nomoto A, Cortez Y, Azhar S. Consequences of over-expression of rat Scavenger Receptor, SR-BI, in an adrenal cell model. Nutr Metab (Lond) 2006; 3:43.
61. Runge KE, Evans JE, He ZY, et al. Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution. Dev Biol 2007; 304:317-325.
62. Kang JH, Park K-K, Lee I-S, et al. Proteome analysis of responses to ascochlorin in a human osteosarcoma cell line by 2-D gel electrophoresis and MALDI-TOF MS. J Proteome Res 2006; 5:2620-2631. The paper describes changes in the protein composition of human osteosarcoma U2OS cells in response to ascochlorin.