New insights into the reductive half-reaction mechanism of aromatic amine dehydrogenase revealed by reaction with carbinolamine substrates

Journal of Biological Chemistry

Volumn 282, Issue 33, 2007, Pages 23766-23777

  Roujeinikova, Anna ^a   Hothi, Parvinder ^a   Masgrau, Laura ^c   Sutcliffe, Michael J ^a,b   Scrutton, Nigel S ^a   Leys, David ^a,b,d  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c INSTITUT PASTEUR   (France)

^d NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBINOLAMINES; KINETIC CRYSTALLOGRAPHY; PROTON TRANSFERS; TRYPTOPHAN TRYPTOPHYLQUINONE (TTQ);

AMINES; CARBOXYLIC ACIDS; CONFORMATIONS; MOLECULAR DYNAMICS; OXIDATION; REACTION KINETICS;

ENZYME KINETICS;

ALDEHYDE; AMINE; AMINE DEHYDROGENASE; AMMONIA; AROMATIC COMPOUND; CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; METHANOLAMINE DERIVATIVE; PHENYLETHANOLAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ADDUCTION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; HYDROLYSIS; OXIDATION; PRIORITY JOURNAL; PROTON TRANSPORT;

ALCALIGENES FAECALIS; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; HALF-LIFE; HYDROLYSIS; KINETICS; METHYLAMINES; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS;

EID: 34547897921     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700677200     Document Type: Article

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