Differential regulation of Akt, caspases and MAP kinases underlies smooth muscle cell apoptosis during aortic remodelling in SHR treated with amlodipine

British Journal of Pharmacology

Volumn 151, Issue 8, 2007, Pages 1315-1323

  Duguay, D ^a   DeBlois, D ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Apoptosis; Calcium channel blockers; Hypertension; Hypertrophy hyperplasia; Smooth muscle cells

Indexed keywords

AMLODIPINE; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; APOPTOSIS; ARTICLE; CELL COUNT; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ESSENTIAL HYPERTENSION; HYPERTROPHY; MALE; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER; SPONTANEOUSLY HYPERTENSIVE RAT;

AMLODIPINE; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; HYPERTROPHY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, INBRED SHR;

EID: 34547889455     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707334     Document Type: Article

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