-
1
-
-
4143052284
-
Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells
-
Arany I, Megyesi JK, Kaneto H, Price PM, Safirstein RL (2004) Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells. Am J Physiol Renal Physiol 287:F543-9
-
(2004)
Am J Physiol Renal Physiol
, vol.287
-
-
Arany, I.1
Megyesi, J.K.2
Kaneto, H.3
Price, P.M.4
Safirstein, R.L.5
-
2
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286:1358-62
-
(1999)
Science
, vol.286
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
3
-
-
0034740214
-
C/EBPβ phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival
-
Buck M, Poli V, Hunter T, Chojkier M (2001) C/EBPβ phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival. Mol Cell 8:807-16
-
(2001)
Mol Cell
, vol.8
, pp. 807-816
-
-
Buck, M.1
Poli, V.2
Hunter, T.3
Chojkier, M.4
-
4
-
-
0027361017
-
Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase
-
Chen RH, Abate C, Blenis J (1993) Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase. Proc Natl Acad Sci USA 90:10952-6
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10952-10956
-
-
Chen, R.H.1
Abate, C.2
Blenis, J.3
-
5
-
-
5044227624
-
Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells
-
Choi BK, Choi CH, Oh HL, Kim YK (2004) Role of ERK activation in cisplatin-induced apoptosis in A172 human glioma cells. Neurotoxicology 25:915-24
-
(2004)
Neurotoxicology
, vol.25
, pp. 915-924
-
-
Choi, B.K.1
Choi, C.H.2
Oh, H.L.3
Kim, Y.K.4
-
6
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley S, Paterson H, Kemp P, Marshall CJ (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841-52
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
7
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S et al. (2002) Mutations of the BRAF gene in human cancer. Nature 417:949-54
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
-
8
-
-
0346995278
-
Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad
-
Eisenmann KM, VanBrocklin MW, Staffend NA, Kitchen SM, Koo HM (2003) Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad. Cancer Res 63:8330-7
-
(2003)
Cancer Res
, vol.63
, pp. 8330-8337
-
-
Eisenmann, K.M.1
VanBrocklin, M.W.2
Staffend, N.A.3
Kitchen, S.M.4
Koo, H.M.5
-
9
-
-
0030063435
-
Evidence for two catalytically active kinase domains in pp90rsk
-
Fisher TL, Blenis J (1996) Evidence for two catalytically active kinase domains in pp90rsk. Mol Cell Biol 16:1212-9
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1212-1219
-
-
Fisher, T.L.1
Blenis, J.2
-
10
-
-
3042596104
-
Human melanocytes do not express EGF receptors
-
Grahn JC, Isseroff RR (2004) Human melanocytes do not express EGF receptors. J Invest Dermatol 123:244-6
-
(2004)
J Invest Dermatol
, vol.123
, pp. 244-246
-
-
Grahn, J.C.1
Isseroff, R.R.2
-
11
-
-
0033053182
-
Phorbol ester-induced mononuclear cell differentiation is blocked by the mitogenactivated protein kinase kinase (MEK) inhibitor PD98059
-
He H, Wang X, Gorospe M, Holbrook NJ, Trush MA (1999) Phorbol ester-induced mononuclear cell differentiation is blocked by the mitogenactivated protein kinase kinase (MEK) inhibitor PD98059. Cell Growth Differ 10:307-15
-
(1999)
Cell Growth Differ
, vol.10
, pp. 307-315
-
-
He, H.1
Wang, X.2
Gorospe, M.3
Holbrook, N.J.4
Trush, M.A.5
-
12
-
-
0033590636
-
Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
-
Hoshino R, Chatani Y, Yamori T, Tsuruo T, Oka H, Yoshida O et al. (1999) Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 18:813-22
-
(1999)
Oncogene
, vol.18
, pp. 813-822
-
-
Hoshino, R.1
Chatani, Y.2
Yamori, T.3
Tsuruo, T.4
Oka, H.5
Yoshida, O.6
-
13
-
-
0028333768
-
Sequential protein kinase reactions controlling cell growth and differentiation
-
Johnson GL, Vaillancourt RR (1994) Sequential protein kinase reactions controlling cell growth and differentiation. Curr Opin Cell Biol 6:230-8
-
(1994)
Curr Opin Cell Biol
, vol.6
, pp. 230-238
-
-
Johnson, G.L.1
Vaillancourt, R.R.2
-
14
-
-
0242441992
-
Expression of activated extracellular signal-regulated kinases 1/2 in malignant melanomas: Relationship with clinical outcome
-
Jorgensen K, Holm R, Maelandsmo GM, Florenes VA (2003) Expression of activated extracellular signal-regulated kinases 1/2 in malignant melanomas: relationship with clinical outcome. Clin Cancer Res 9:5325-31
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5325-5331
-
-
Jorgensen, K.1
Holm, R.2
Maelandsmo, G.M.3
Florenes, V.A.4
-
15
-
-
0027283659
-
-
Lenormand P, Sardet C, Pages G, L'Allemain G, Brunet A, Pouyssegur J (1993) Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J Cell Biol 122:1079-88
-
Lenormand P, Sardet C, Pages G, L'Allemain G, Brunet A, Pouyssegur J (1993) Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J Cell Biol 122:1079-88
-
-
-
-
16
-
-
0038339253
-
-
Losa JH, Parada Cobo C, Viniegra JG, Sanchez-Arevalo Lobo VJ, Ramon y Cajal S, Sanchez-Prieto R (2003) Role of the p38 MAPK pathway in cisplatin-based therapy. Oncogene 22:3998-4006
-
Losa JH, Parada Cobo C, Viniegra JG, Sanchez-Arevalo Lobo VJ, Ramon y Cajal S, Sanchez-Prieto R (2003) Role of the p38 MAPK pathway in cisplatin-based therapy. Oncogene 22:3998-4006
-
-
-
-
17
-
-
33748802513
-
STAT5 phosphorylation in malignant melanoma is mediated through SRC and JAK1 kinases and exerts anti-apoptotic effects
-
Mirmohammadsadegh A, Hassan M, Bardenheuer W, Marini A, Gustrau A, Nambiar S et al. (2006) STAT5 phosphorylation in malignant melanoma is mediated through SRC and JAK1 kinases and exerts anti-apoptotic effects. J Invest Dermatol 126:2272-80
-
(2006)
J Invest Dermatol
, vol.126
, pp. 2272-2280
-
-
Mirmohammadsadegh, A.1
Hassan, M.2
Bardenheuer, W.3
Marini, A.4
Gustrau, A.5
Nambiar, S.6
-
18
-
-
24344489052
-
Constitutive expression of EGF receptors on normal human melanocytes
-
Mirmohammadsadegh A, Hassan M, Gustrau A, Doroudi R, Schmittner N, Nambiar S et al. (2005) Constitutive expression of EGF receptors on normal human melanocytes. J Invest Dermatol 125:392-4
-
(2005)
J Invest Dermatol
, vol.125
, pp. 392-394
-
-
Mirmohammadsadegh, A.1
Hassan, M.2
Gustrau, A.3
Doroudi, R.4
Schmittner, N.5
Nambiar, S.6
-
19
-
-
0032949934
-
Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: Inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin
-
Persons DL, Yazlovitskaya EM, Cui W, Pelling JC (1999) Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. Clin Cancer Res 5:1007-14
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1007-1014
-
-
Persons, D.L.1
Yazlovitskaya, E.M.2
Cui, W.3
Pelling, J.C.4
-
20
-
-
0037228055
-
High frequency of BRAF mutations in nevi
-
Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, Robbins CM et al. (2003) High frequency of BRAF mutations in nevi. Nat Genet 33:19-20
-
(2003)
Nat Genet
, vol.33
, pp. 19-20
-
-
Pollock, P.M.1
Harper, U.L.2
Hansen, K.S.3
Yudt, L.M.4
Stark, M.5
Robbins, C.M.6
-
21
-
-
0030898417
-
Mitogen-activated protein kinase pathways
-
Robinson MJ, Cobb MH (1997) Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 9:180-6
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 180-186
-
-
Robinson, M.J.1
Cobb, M.H.2
-
22
-
-
0038112035
-
Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity
-
Roux PP, Richards SA, Blenis J (2003) Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity. Mol Cell Biol 23:4796-804
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4796-4804
-
-
Roux, P.P.1
Richards, S.A.2
Blenis, J.3
-
23
-
-
0033529706
-
Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3
-
Sassone-Corsi P, Mizzen CA, Cheung P, Crosio C, Monaco L, Jacquot S et al. (1999) Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3. Science 285:886-91
-
(1999)
Science
, vol.285
, pp. 886-891
-
-
Sassone-Corsi, P.1
Mizzen, C.A.2
Cheung, P.3
Crosio, C.4
Monaco, L.5
Jacquot, S.6
-
24
-
-
0031007867
-
IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase
-
Schouten GJ, Vertegaal AC, Whiteside ST, Israel A, Toebes M, Dorsman JC et al. (1997) IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase. EMBO J 16:3133-44
-
(1997)
EMBO J
, vol.16
, pp. 3133-3144
-
-
Schouten, G.J.1
Vertegaal, A.C.2
Whiteside, S.T.3
Israel, A.4
Toebes, M.5
Dorsman, J.C.6
-
25
-
-
0037006414
-
Association between functional polymorphism in EGF gene and malignant melanoma
-
Shahbazi M, Pravica V, Nasreen N, Fakhoury H, Fryer AA, Strange RC et al. (2002) Association between functional polymorphism in EGF gene and malignant melanoma. Lancet 359:397-401
-
(2002)
Lancet
, vol.359
, pp. 397-401
-
-
Shahbazi, M.1
Pravica, V.2
Nasreen, N.3
Fakhoury, H.4
Fryer, A.A.5
Strange, R.C.6
-
27
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
Siddik ZH (2003) Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 22:7265-7
-
(2003)
Oncogene
, vol.22
, pp. 7265-7267
-
-
Siddik, Z.H.1
-
28
-
-
0141922028
-
The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation
-
Stove C, Stove V, Derycke L, Van Marck V, Mareel M, Bracke M (2003) The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation. J Invest Dermatol 121:802-12
-
(2003)
J Invest Dermatol
, vol.121
, pp. 802-812
-
-
Stove, C.1
Stove, V.2
Derycke, L.3
Van Marck, V.4
Mareel, M.5
Bracke, M.6
-
29
-
-
0034671751
-
Requirement for ERK activation in cisplatin-induced apoptosis
-
Wang X, Martindale JL, Holbrook NJ (2000) Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem 275: 39435-39443
-
(2000)
J Biol Chem
, vol.275
, pp. 39435-39443
-
-
Wang, X.1
Martindale, J.L.2
Holbrook, N.J.3
-
30
-
-
3142583282
-
Role of ERK1/2 kinase in cisplatin-induced apoptosis in human ovarian carcinoma cells
-
Wei SQ, Sui LH, Zheng JH, Zhang GM, Kao YL (2004) Role of ERK1/2 kinase in cisplatin-induced apoptosis in human ovarian carcinoma cells. Chin Med Sci J 19:125-9
-
(2004)
Chin Med Sci J
, vol.19
, pp. 125-129
-
-
Wei, S.Q.1
Sui, L.H.2
Zheng, J.H.3
Zhang, G.M.4
Kao, Y.L.5
-
31
-
-
0036452342
-
Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines
-
Woessmann W, Chen X, Borkhardt A (2002) Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines. Cancer Chenother Pharmacol 50:97-404
-
(2002)
Cancer Chenother Pharmacol
, vol.50
, pp. 97-404
-
-
Woessmann, W.1
Chen, X.2
Borkhardt, A.3
-
32
-
-
13244291452
-
The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway
-
Wu YJ, Muldoon LL, Neuwelt EA (2005) The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway. J Pharmacol Exp Ther 312:424-31
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 424-431
-
-
Wu, Y.J.1
Muldoon, L.L.2
Neuwelt, E.A.3
-
33
-
-
0029789643
-
Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
-
Xing J, Ginty DD, Greenberg ME (1996) Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 273:959-63
-
(1996)
Science
, vol.273
, pp. 959-963
-
-
Xing, J.1
Ginty, D.D.2
Greenberg, M.E.3
|