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Volumn 804, Issue , 1996, Pages 588-611

Non-genotoxic hepatocarcinogenesis: Suppression of apoptosis by peroxisome proliferators

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; INOSITOL PHOSPHATE; PEROXISOME PROLIFERATOR; PROTEIN KINASE C; TRANSCRIPTION FACTOR;

EID: 0030462771     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb18647.x     Document Type: Conference Paper
Times cited : (38)

References (97)
  • 1
    • 0018888058 scopus 로고
    • Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
    • REDDY, J. K., D. L. AZARNOFF & C. E. HIGNITE. 1980. Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature 283: 397-398.
    • (1980) Nature , vol.283 , pp. 397-398
    • Reddy, J.K.1    Azarnoff, D.L.2    Hignite, C.E.3
  • 2
    • 0026100678 scopus 로고
    • Peroxisome proliferation and non-genotoxic carcinogenesis: Commentary on a symposium
    • MOODY, D. E., J. K. REDDY, B. G. LAKE, J. A. POPP & D. H. REESE. 1991. Peroxisome proliferation and non-genotoxic carcinogenesis: Commentary on a symposium. Fund. Appl. Toxicol. 6: 233-248.
    • (1991) Fund. Appl. Toxicol. , vol.6 , pp. 233-248
    • Moody, D.E.1    Reddy, J.K.2    Lake, B.G.3    Popp, J.A.4    Reese, D.H.5
  • 4
    • 0025168534 scopus 로고
    • Cell proliferation in carcinogenesis
    • COHEN, S. M. & L. B. ELLWEIN. 1989. Cell proliferation in carcinogenesis. Science 249: 1007-1011.
    • (1989) Science , vol.249 , pp. 1007-1011
    • Cohen, S.M.1    Ellwein, L.B.2
  • 5
    • 0003223306 scopus 로고
    • Apoptosis: A widespread process involved in liver adaptation and carcinogenesis
    • I. M. Arias, J. L. Boyer, N. Fausto, W. B. Jakoby, D. Schachter & D. A. Shafritz, Eds. Raven Press. New York
    • OBERHAMMER, F. A. & R. A. ROBERTS. 1994. Apoptosis: A widespread process involved in liver adaptation and carcinogenesis. In The Liver: Biology and Pathobiology. I. M. Arias, J. L. Boyer, N. Fausto, W. B. Jakoby, D. Schachter & D. A. Shafritz, Eds. 1547-1556. Raven Press. New York.
    • (1994) The Liver: Biology and Pathobiology , pp. 1547-1556
    • Oberhammer, F.A.1    Roberts, R.A.2
  • 6
    • 0028931999 scopus 로고
    • Apoptosis: Regulation and relevance to toxicology
    • ALISON, M. R. & C. E. SARRAF. 1995. Apoptosis: Regulation and relevance to toxicology. Hum. Exp. Toxicol. 14: 234-247.
    • (1995) Hum. Exp. Toxicol. , vol.14 , pp. 234-247
    • Alison, M.R.1    Sarraf, C.E.2
  • 8
    • 0025220542 scopus 로고
    • Effects of the hypolipidaemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver
    • GERBRACHT, U., W. BURSCH, P. KRAUS, B. PUTZ, M. REINACHER, I. TIMMERMAN-TROSIENER & R. SCHULTE-HERMANN. 1990. Effects of the hypolipidaemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver. Carcinogenesis 11: 617-624.
    • (1990) Carcinogenesis , vol.11 , pp. 617-624
    • Gerbracht, U.1    Bursch, W.2    Kraus, P.3    Putz, B.4    Reinacher, M.5    Timmerman-Trosiener, I.6    Schulte-Hermann, R.7
  • 9
    • 0027537546 scopus 로고
    • Non-genotoxic hepatocarcinogenesis in vitro: The FaO hepatoma line responds to peroxisome proliferators and retains the ability to undergo apoptosis
    • BAYLY, A. C., N. J. FRENCH, C. DIVE & R. A. ROBERTS. 1993. Non-genotoxic hepatocarcinogenesis in vitro: The FaO hepatoma line responds to peroxisome proliferators and retains the ability to undergo apoptosis. J. Cell Sci. 104: 307-315.
    • (1993) J. Cell Sci. , vol.104 , pp. 307-315
    • Bayly, A.C.1    French, N.J.2    Dive, C.3    Roberts, R.A.4
  • 10
    • 0028208243 scopus 로고
    • Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator, nafenopin
    • BAYLY, A. C., R. A. ROBERTS & C. DIVE. 1994. Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator, nafenopin. J. Cell Biol. 125: 197-203.
    • (1994) J. Cell Biol. , vol.125 , pp. 197-203
    • Bayly, A.C.1    Roberts, R.A.2    Dive, C.3
  • 11
    • 0028587320 scopus 로고
    • The peroxisome proliferator class of non-genotoxic hepatocarcinogens synergise with epidermal growth factor to promote the clonal expansion of initiated rat hepatocytes
    • JAMES, N. H. & R. A. ROBERTS. 1994. The peroxisome proliferator class of non-genotoxic hepatocarcinogens synergise with epidermal growth factor to promote the clonal expansion of initiated rat hepatocytes. Carcinogenesis 15: 2687-2694.
    • (1994) Carcinogenesis , vol.15 , pp. 2687-2694
    • James, N.H.1    Roberts, R.A.2
  • 12
    • 77957177377 scopus 로고
    • Species differences in clonal expansion of hepatocytes in response to the co-action of epidermal growth factor and nafenopin, a rodent hepatocarcinogenic peroxisome proliferator
    • in press
    • JAMES, N. H. & N. H. ROBERTS. 1995. Species differences in clonal expansion of hepatocytes in response to the co-action of epidermal growth factor and nafenopin, a rodent hepatocarcinogenic peroxisome proliferator. Fund. Appl. Toxicol. 25: in press.
    • (1995) Fund. Appl. Toxicol. , vol.25
    • James, N.H.1    Roberts, N.H.2
  • 13
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • ISSEMANN, I. & S. GREEN. 1990. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347: 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 14
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl coA oxidase gene
    • TUGWOOD, J. D., I. ISSEMANN, R. G. ANDERSON, K. R. BUNDELL, W. L. MCPHEAT & S. GREEN. 1992. The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl coA oxidase gene. EMBO J. 11: 433-439.
    • (1992) EMBO J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundell, K.R.4    Mcpheat, W.L.5    Green, S.6
  • 15
    • 0028953133 scopus 로고
    • Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription
    • ALDRIDGE, T. C., J. D. TUGWOOD & S. GREEN. 1995. Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription. Biochem. J. 306: 473-479.
    • (1995) Biochem. J. , vol.306 , pp. 473-479
    • Aldridge, T.C.1    Tugwood, J.D.2    Green, S.3
  • 16
    • 0000973407 scopus 로고
    • Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP
    • ASHBY, J. & R. TENNANT. 1991. Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutat. Res. 257: 229-306.
    • (1991) Mutat. Res. , vol.257 , pp. 229-306
    • Ashby, J.1    Tennant, R.2
  • 17
    • 0021051308 scopus 로고
    • Carcinogenesis by hepatic peroxisome proliferators. Evaluation of the risk of hypolidaemic drugs and industrial plasticizers to humans
    • REDDY, J. K. & N. D. LALWANI. 1983. Carcinogenesis by hepatic peroxisome proliferators. Evaluation of the risk of hypolidaemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol. 12: 1-58.
    • (1983) Crit. Rev. Toxicol. , vol.12 , pp. 1-58
    • Reddy, J.K.1    Lalwani, N.D.2
  • 18
    • 0024241608 scopus 로고
    • Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-pyramidinylthio]acetic acid (Wyeth-14,643) in rats
    • MARSMANN, D. S., R. C. CATTLEY, J. G. CONWAY & J. A. POPP. 1988. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-pyramidinylthio]acetic acid (Wyeth-14,643) in rats. Cancer Res. 48: 6739-6744.
    • (1988) Cancer Res. , vol.48 , pp. 6739-6744
    • Marsmann, D.S.1    Cattley, R.C.2    Conway, J.G.3    Popp, J.A.4
  • 19
    • 0022335175 scopus 로고
    • Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene: A biochemical human hazard assessment
    • ELCOMBE, C. R. 1985. Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene: A biochemical human hazard assessment. Arch. Toxicol.: 6-7.
    • (1985) Arch. Toxicol. , pp. 6-7
    • Elcombe, C.R.1
  • 21
    • 0018345144 scopus 로고
    • Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator Wy-14,643 in rat and mouse liver
    • REDDY, J. K., M. S. RAO, D. L. AZARNOFF & S. SELL. 1979. Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator Wy-14,643 in rat and mouse liver. Cancer Res. 39: 152-160.
    • (1979) Cancer Res. , vol.39 , pp. 152-160
    • Reddy, J.K.1    Rao, M.S.2    Azarnoff, D.L.3    Sell, S.4
  • 24
    • 0022924249 scopus 로고
    • Peroxisome proliferation due to di(2-ethylhexyl)-phthalate: Species differences and possible mechanisms
    • ELCOMBE, C. R. & A. MITCHELL. 1986. Peroxisome proliferation due to di(2-ethylhexyl)-phthalate: Species differences and possible mechanisms. Environ. Health Perspect. 70: 211-219.
    • (1986) Environ. Health Perspect. , vol.70 , pp. 211-219
    • Elcombe, C.R.1    Mitchell, A.2
  • 25
    • 0024410242 scopus 로고
    • Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig and marmoset
    • LAKE, B. G., J. G. EVANS, T. J. B. GRAY, S. A. KÖRÖSI & C. J. NORTH. 1989. Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig and marmoset. Toxicol. Appl. Pharmacol. 99: 148-160.
    • (1989) Toxicol. Appl. Pharmacol. , vol.99 , pp. 148-160
    • Lake, B.G.1    Evans, J.G.2    Gray, T.J.B.3    Körösi, S.A.4    North, C.J.5
  • 26
    • 0022530582 scopus 로고
    • Hepatic peroxisomal changes induced by tetrazole-substituted alkoxyacetophenone in rats and comparison with other species
    • EACHO, P. I., P. S., FOXWORTHY, R. D. DILLARD, C. A. WHITESITT, D. K. HERRON & W. S. MARSHALL. 1986. Hepatic peroxisomal changes induced by tetrazole-substituted alkoxyacetophenone in rats and comparison with other species. Toxicol. Appl. Pharmacol. 83: 430-437.
    • (1986) Toxicol. Appl. Pharmacol. , vol.83 , pp. 430-437
    • Eacho, P.I.1    Foxworthy, P.S.2    Dillard, R.D.3    Whitesitt, C.A.4    Herron, D.K.5    Marshall, W.S.6
  • 27
    • 0024504510 scopus 로고
    • Species differences in the effects of bezafibrate, a hypolipidaemic agent, on hepatic peroxisome associated enzymes
    • WATANABE, T., S. HORIE, J. YAMADA, M. ISAJI, T. NISHIGAKI, J. NAITO & T. SUGA. 1989. Species differences in the effects of bezafibrate, a hypolipidaemic agent, on hepatic peroxisome associated enzymes. Biochem. Pharmacol. 38: 430-437.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 430-437
    • Watanabe, T.1    Horie, S.2    Yamada, J.3    Isaji, M.4    Nishigaki, T.5    Naito, J.6    Suga, T.7
  • 28
    • 0025183341 scopus 로고
    • Effects of ciprofibrate, bezafibrate and LY171883 on peroxisomal beta-oxidation in cultured rat, dog and rhesus monkey hepatocytes
    • FOXWORTHY, P. S., S. L. WHITE, D. M. HOOVER & P. I. EACHO. 1990. Effects of ciprofibrate, bezafibrate and LY171883 on peroxisomal beta-oxidation in cultured rat, dog and rhesus monkey hepatocytes. Toxicol. Appl. Pharmacol. 104: 386-394.
    • (1990) Toxicol. Appl. Pharmacol. , vol.104 , pp. 386-394
    • Foxworthy, P.S.1    White, S.L.2    Hoover, D.M.3    Eacho, P.I.4
  • 29
    • 0026085519 scopus 로고
    • Comparative induction of cytochrome P450IVA1 and peroxisome proliferation by ciprofibrate in the rat and marmoset
    • MAKOWSKA, J. M., F. W. BONNER & G. G. GIBSON. 1991. Comparative induction of cytochrome P450IVA1 and peroxisome proliferation by ciprofibrate in the rat and marmoset. Arch. Toxicol. 65: 106-113.
    • (1991) Arch. Toxicol. , vol.65 , pp. 106-113
    • Makowska, J.M.1    Bonner, F.W.2    Gibson, G.G.3
  • 30
    • 0024213976 scopus 로고
    • Stimulation of DNA synthesis but not of peroxisomal beta-oxidation by nafenopin in primary cultures of marmoset hepatocytes
    • BIERI, F., W. STAUBLI, F. WAECHTER, S. MUAKKASAH-KELLY & P. BENTLEY. 1988. Stimulation of DNA synthesis but not of peroxisomal beta-oxidation by nafenopin in primary cultures of marmoset hepatocytes. Cell Biol. Int. Rep. 12: 1077-1087.
    • (1988) Cell Biol. Int. Rep. , vol.12 , pp. 1077-1087
    • Bieri, F.1    Staubli, W.2    Waechter, F.3    Muakkasah-Kelly, S.4    Bentley, P.5
  • 31
    • 0020683937 scopus 로고
    • Relationship between morphological changes and lipid lowering action of p-chlorophenoxyisobutyric acid (CPIB) on hepatic mitochondria and peroxisomes in man
    • HANEFELD, M., C. HEMMER & E. KADNER. 1983. Relationship between morphological changes and lipid lowering action of p-chlorophenoxyisobutyric acid (CPIB) on hepatic mitochondria and peroxisomes in man. Atherosclerosis. 46: 239-246.
    • (1983) Atherosclerosis , vol.46 , pp. 239-246
    • Hanefeld, M.1    Hemmer, C.2    Kadner, E.3
  • 32
    • 0025163524 scopus 로고
    • Too many rodent carcinogens: Mitogenesis increases mutagenesis
    • AMES, B. N. & L. S. GOLD. 1990. Too many rodent carcinogens: Mitogenesis increases mutagenesis. Science 249: 970-971.
    • (1990) Science , vol.249 , pp. 970-971
    • Ames, B.N.1    Gold, L.S.2
  • 33
    • 0024430314 scopus 로고
    • Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis
    • REDDY, J. K. & M. S. RAO. 1989. Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis. Mutat. Res. 214: 63-68.
    • (1989) Mutat. Res. , vol.214 , pp. 63-68
    • Reddy, J.K.1    Rao, M.S.2
  • 34
    • 0028084568 scopus 로고
    • Oxidative DNA damage - The effects of certain genotixic and operationally non-genotoxic carcinogens
    • CLAYSON, D. P., R. MEHTA & F. IVERSON. 1994. Oxidative DNA damage - the effects of certain genotixic and operationally non-genotoxic carcinogens. Mutat. Res. 317: 25-42.
    • (1994) Mutat. Res. , vol.317 , pp. 25-42
    • Clayson, D.P.1    Mehta, R.2    Iverson, F.3
  • 35
    • 0024241608 scopus 로고
    • Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyramidinylthio]acetic acid (Wy-14,643) in rats
    • MARSMAN, D. S., C. C. RUSSELL, R. C. CATTLEY, J. G. CONWAY & J. A. POPP. 1988. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyramidinylthio]acetic acid (Wy-14,643) in rats. Cancer Res. 48: 6739-6744.
    • (1988) Cancer Res. , vol.48 , pp. 6739-6744
    • Marsman, D.S.1    Russell, C.C.2    Cattley, R.C.3    Conway, J.G.4    Popp, J.A.5
  • 36
    • 0025832995 scopus 로고
    • Age-related susceptibility to the carcinogenic effects of the peroxisome proliferator, Wy-14,643 in rat liver
    • CATTLEY, R. C., D. S. MARSMANN & J. A. POPP. 1991. Age-related susceptibility to the carcinogenic effects of the peroxisome proliferator, Wy-14,643 in rat liver. Carcinogenesis 12: 469-473.
    • (1991) Carcinogenesis , vol.12 , pp. 469-473
    • Cattley, R.C.1    Marsmann, D.S.2    Popp, J.A.3
  • 37
    • 0026014061 scopus 로고
    • Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously
    • KRAUPP-GRASSL, D., W. HUBER, H. TAPER & R. SCHULTE-HERMANN. 1991. Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously. Cancer Res. 51: 666-671.
    • (1991) Cancer Res. , vol.51 , pp. 666-671
    • Kraupp-Grassl, D.1    Huber, W.2    Taper, H.3    Schulte-Hermann, R.4
  • 38
    • 0022273906 scopus 로고
    • Differential repair of 04-alkylthymidine following exposure to methylating and ethylating hepatocarcinogens
    • RICHARDSON, F. C., M. C. DYROFF, J. A. BOUCHERON & J. A. SWENBERG. 1985. Differential repair of 04-alkylthymidine following exposure to methylating and ethylating hepatocarcinogens. Carcinogenesis 6: 625-629.
    • (1985) Carcinogenesis , vol.6 , pp. 625-629
    • Richardson, F.C.1    Dyroff, M.C.2    Boucheron, J.A.3    Swenberg, J.A.4
  • 39
    • 77957174646 scopus 로고
    • Relationship between hepatocyte necrosis, proliferation and initation induced by diethylnitrosamine in the male F344 rat
    • KATO, M., J. A. POPP, R. B. CONOLLY & R. C. CATTLEY. 1993. Relationship between hepatocyte necrosis, proliferation and initation induced by diethylnitrosamine in the male F344 rat. Fund. App. Tox. 20: 155-162.
    • (1993) Fund. App. Tox. , vol.20 , pp. 155-162
    • Kato, M.1    Popp, J.A.2    Conolly, R.B.3    Cattley, R.C.4
  • 40
    • 0028175461 scopus 로고
    • The antiandrogen cyproterone acetate: Discovery, chemistry basic pharmacology, clinical use and tool in basic research
    • NEUMANN, F. 1994. The antiandrogen cyproterone acetate: Discovery, chemistry basic pharmacology, clinical use and tool in basic research. Exp. Clin. Endocrinol. 102: 1-32.
    • (1994) Exp. Clin. Endocrinol. , vol.102 , pp. 1-32
    • Neumann, F.1
  • 41
    • 0021248961 scopus 로고
    • Controlled death (apoptosis) of normal and preneoplastic cells in rat liver following withdrawal of tumor promoters
    • BURSCH, B., B. LAUER, I. TIMMERMAN-TROSIENER, G. BARTHEL, J. SCHUPPLER & R. SCHULTE-HERMANN. 1984. Controlled death (apoptosis) of normal and preneoplastic cells in rat liver following withdrawal of tumor promoters. Carcinogenesis 5: 453-458.
    • (1984) Carcinogenesis , vol.5 , pp. 453-458
    • Bursch, B.1    Lauer, B.2    Timmerman-Trosiener, I.3    Barthel, G.4    Schuppler, J.5    Schulte-Hermann, R.6
  • 42
    • 0022883810 scopus 로고
    • Growth, regression and cell death in rat liver as related to tissue levels of the hepatomitogen cyproterone acetate
    • BURSCH, W., B. DUSTERBERG & R. SCHULTE-HERMANN. 1986. Growth, regression and cell death in rat liver as related to tissue levels of the hepatomitogen cyproterone acetate. Arch. Toxicol. 59: 221-227.
    • (1986) Arch. Toxicol. , vol.59 , pp. 221-227
    • Bursch, W.1    Dusterberg, B.2    Schulte-Hermann, R.3
  • 43
    • 0026599985 scopus 로고
    • Cell death by apoptosis and its protective role against disease
    • BURSCH, W., F. OBERHAMMER & R. SCHULTE-HERMANN. 1992. Cell death by apoptosis and its protective role against disease. Trends Physiol. Sci. 13: 245-251.
    • (1992) Trends Physiol. Sci. , vol.13 , pp. 245-251
    • Bursch, W.1    Oberhammer, F.2    Schulte-Hermann, R.3
  • 44
    • 0029081713 scopus 로고
    • Non-genotoxic hepatocarcinogens induce DNA synthesis and their withdrawal induces apoptosis but in discrete hepatocyte populations
    • In press
    • ROBERTS, R. A., A. R. SOAMES, J. H. GILL, N. H. JAMES & E. B. WHEELDON. 1995. Non-genotoxic hepatocarcinogens induce DNA synthesis and their withdrawal induces apoptosis but in discrete hepatocyte populations. Carcinogenesis. In press.
    • (1995) Carcinogenesis
    • Roberts, R.A.1    Soames, A.R.2    Gill, J.H.3    James, N.H.4    Wheeldon, E.B.5
  • 46
    • 0027479796 scopus 로고
    • Apoptosis (The Frank Rose Memorial Lecture)
    • WYLLIE, A. H. 1993. Apoptosis (The Frank Rose Memorial Lecture). Br. J. Cancer 67: 205-208.
    • (1993) Br. J. Cancer , vol.67 , pp. 205-208
    • Wyllie, A.H.1
  • 47
    • 0001971145 scopus 로고
    • Cell death and the disease process: Role of calcium
    • I. D. Bowen & R. A. Lockshin, Eds.: Chapman and Hall
    • TRUMP, B. F., I. I. K. BEREZESKY & A. R. OSORNIO-VARGAS. 1981. Cell death and the disease process: Role of calcium. In Cell Death in Biology and Pathology. I. D. Bowen & R. A. Lockshin, Eds.: 209-241. Chapman and Hall.
    • (1981) Cell Death in Biology and Pathology , pp. 209-241
    • Trump, B.F.1    Berezesky, I.I.K.2    Osornio-Vargas, A.R.3
  • 48
    • 0018830636 scopus 로고
    • Glucocorticoid induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • WYLLIE, A. H. 1980. Glucocorticoid induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 4: 555-556.
    • (1980) Nature , vol.4 , pp. 555-556
    • Wyllie, A.H.1
  • 49
    • 0028939862 scopus 로고
    • The genetic regulation of apoptosis
    • WYLLIE, A. H. 1995. The genetic regulation of apoptosis. Curr. Opin. Gen. Devel. 5: 97-104.
    • (1995) Curr. Opin. Gen. Devel. , vol.5 , pp. 97-104
    • Wyllie, A.H.1
  • 51
    • 0026689242 scopus 로고
    • Apoptosis: A different type of cell death
    • GERSCHENSON, L. E. & R. J. ROTELLO. 1992. Apoptosis: A different type of cell death. FASEB J. 6: 2450-2455.
    • (1992) FASEB J. , vol.6 , pp. 2450-2455
    • Gerschenson, L.E.1    Rotello, R.J.2
  • 52
    • 0023096315 scopus 로고
    • Early development of protein metabolic perturbations in the liver and skeletal muscle of tumour-bearing rats. A model system for cancer cachexia
    • TESSITORE, L., G. BONELLI & F M. BACCINO. 1987. Early development of protein metabolic perturbations in the liver and skeletal muscle of tumour-bearing rats. A model system for cancer cachexia. Biochem. J. 241: 153-159.
    • (1987) Biochem. J. , vol.241 , pp. 153-159
    • Tessitore, L.1    Bonelli, G.2    Baccino, F.M.3
  • 53
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • SCHWARTZMAN, R. A. & J. A. CIDLOWSKI. 1993. Apoptosis: The biochemistry and molecular biology of programmed cell death. Endocrine Rev. 14: 133-151.
    • (1993) Endocrine Rev. , vol.14 , pp. 133-151
    • Schwartzman, R.A.1    Cidlowski, J.A.2
  • 54
    • 0028836119 scopus 로고
    • The rodent non-genotoxic hepatocarcinogen nafenopin and EGF alter the mitosis/apoptosis balance promoting hepatoma clonal growth
    • In Press
    • GILL, J. H., C. M. MOLLOY, K. SHOESMITH, A. C. BAYLY & R. A. ROBERTS. 1995. The rodent non-genotoxic hepatocarcinogen nafenopin and EGF alter the mitosis/apoptosis balance promoting hepatoma clonal growth. Cell Death and Differentiation. In Press.
    • (1995) Cell Death and Differentiation
    • Gill, J.H.1    Molloy, C.M.2    Shoesmith, K.3    Bayly, A.C.4    Roberts, R.A.5
  • 55
    • 0025247903 scopus 로고
    • Apoptosis: The role of the endonuclease
    • ARENDS, M. J., R. G. MORRIS & A. H. WYLLIE. 1990. Apoptosis: The role of the endonuclease. Am. J. Pathol. 136: 593-608.
    • (1990) Am. J. Pathol. , vol.136 , pp. 593-608
    • Arends, M.J.1    Morris, R.G.2    Wyllie, A.H.3
  • 58
    • 0025823502 scopus 로고
    • The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells
    • BOE, R., B. T. GJERTSEN, O. K. VINTERMYR, G. HOUGE & S. O. DOSKELAND. 1991. The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells. Exp. Cell Res. 195: 237-246.
    • (1991) Exp. Cell Res. , vol.195 , pp. 237-246
    • Boe, R.1    Gjertsen, B.T.2    Vintermyr, O.K.3    Houge, G.4    Doskeland, S.O.5
  • 59
    • 0027419446 scopus 로고
    • Delayed internucleosomal DNA fragmentation in programmed cell death
    • ZAKERI, Z. F., D. QUAGLINO, T. LATHAM & R. A. LOCKSHIN. 1993. Delayed internucleosomal DNA fragmentation in programmed cell death. FASEB J. 7: 470-478.
    • (1993) FASEB J. , vol.7 , pp. 470-478
    • Zakeri, Z.F.1    Quaglino, D.2    Latham, T.3    Lockshin, R.A.4
  • 60
  • 61
    • 0027217084 scopus 로고
    • Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50Kb fragments prior to or in the absence of internucleosomal fragmentation
    • OBERHAMMER, F., J. W. WILSON, C. DIVE, I. D. MORRIS, J. A. H. HICKMAN, A. E. WAKELING & P. R. WALKER. 1993. Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50Kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12: 3679-3684.
    • (1993) EMBO J. , vol.12 , pp. 3679-3684
    • Oberhammer, F.1    Wilson, J.W.2    Dive, C.3    Morris, I.D.4    Hickman, J.A.H.5    Wakeling, A.E.6    Walker, P.R.7
  • 62
    • 0027479655 scopus 로고
    • Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
    • BROWN, D. G., X.-M. SUN & G. M. COHEN. 1993. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268: 3037-3039.
    • (1993) J. Biol. Chem. , vol.268 , pp. 3037-3039
    • Brown, D.G.1    Sun, X.-M.2    Cohen, G.M.3
  • 63
    • 0025317569 scopus 로고
    • Periodicity of DNA folding in higher order chromatin structures
    • FILIPSKI, J., J. LEBLANC, J. YOUDALE, M. SIKORSKA & P. R. WALKER. 1990. Periodicity of DNA folding in higher order chromatin structures. EMBO J. 9: 1319-1327.
    • (1990) EMBO J. , vol.9 , pp. 1319-1327
    • Filipski, J.1    Leblanc, J.2    Youdale, J.3    Sikorska, M.4    Walker, P.R.5
  • 64
    • 0027138785 scopus 로고
    • Detection of the initial stages of DNA fragmentation in apoptosis
    • WALKER, P. R., L. KOKILEVA, J. LEBLANC & M. SIKORSKA. 1993. Detection of the initial stages of DNA fragmentation in apoptosis. Biotechniques 15: 1032-1040.
    • (1993) Biotechniques , vol.15 , pp. 1032-1040
    • Walker, P.R.1    Kokileva, L.2    Leblanc, J.3    Sikorska, M.4
  • 65
    • 0027658225 scopus 로고
    • Role of proteolysis in apoptosis: Involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes
    • WEAVER, A. M., B. LACH, P. R. WALKER & M. SIKORSKA. 1993. Role of proteolysis in apoptosis: Involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes. Biochem. Cell Biol. 71: 488-500.
    • (1993) Biochem. Cell Biol. , vol.71 , pp. 488-500
    • Weaver, A.M.1    Lach, B.2    Walker, P.R.3    Sikorska, M.4
  • 67
    • 0025265601 scopus 로고
    • Sequential changes in epidermal growth factor receptors/ligand function in cultured rat liver epithelial cells transformed chemically in vitro
    • GRISHAM, J. W., M. TASAO, D. C. LEE & H. SHELTON. 1990. Sequential changes in epidermal growth factor receptors/ligand function in cultured rat liver epithelial cells transformed chemically in vitro. Pathobiol. Neoplasia 58: 3-14.
    • (1990) Pathobiol. Neoplasia , vol.58 , pp. 3-14
    • Grisham, J.W.1    Tasao, M.2    Lee, D.C.3    Shelton, H.4
  • 68
    • 0025017929 scopus 로고
    • Pretranslational and posttranslational regulation of the EGF receptor during the prereplicative phase of liver regeneration
    • JOHANSSON, S., N. ANDERSSON & G. ANDERSSON. 1990. Pretranslational and posttranslational regulation of the EGF receptor during the prereplicative phase of liver regeneration. Hepatol. 12: 533-541.
    • (1990) Hepatol. , vol.12 , pp. 533-541
    • Johansson, S.1    Andersson, N.2    Andersson, G.3
  • 69
    • 0028231893 scopus 로고
    • Apoptosis is inversely related to necrosis and determines net growth rate in tumours bearing constitutively expressed myc, ras and HPV oncogenes
    • ARENDS, M. J., A. J. MCGREGOR & A. WYLLIE. 1994. Apoptosis is inversely related to necrosis and determines net growth rate in tumours bearing constitutively expressed myc, ras and HPV oncogenes. Am. J. Pathol. 144: 1047-1057.
    • (1994) Am. J. Pathol. , vol.144 , pp. 1047-1057
    • Arends, M.J.1    Mcgregor, A.J.2    Wyllie, A.3
  • 70
    • 0025370064 scopus 로고
    • Clonal adaptation during carcinogenesis
    • FARBER, E. 1990. Clonal adaptation during carcinogenesis. Biochem. Pharmacol. 39: 1837-1846.
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 1837-1846
    • Farber, E.1
  • 71
    • 0027326293 scopus 로고
    • Ciprofibrate, a carcinogenic peroxisome proliferator, increases the phosphorylation of the epidermal growth factor receptor
    • ORELLANA, A., L. LOLUIGUE, P. C. HIDALGO, V. FAUNDEZ, A. GONZALEZ & M. BRONFMAN. 1993. Ciprofibrate, a carcinogenic peroxisome proliferator, increases the phosphorylation of the epidermal growth factor receptor. Eur. J. Biochem. 215: 903-906.
    • (1993) Eur. J. Biochem. , vol.215 , pp. 903-906
    • Orellana, A.1    Loluigue, L.2    Hidalgo, P.C.3    Faundez, V.4    Gonzalez, A.5    Bronfman, M.6
  • 73
    • 0027365688 scopus 로고
    • Peroxisomal enzyme induction uncoupled from enhanced DNA synthesis in putative preneoplastic foci of rats treated with a single dose of the peroxisome proliferator, nafenopin
    • KRAUPP-GRASL, B., W. HUBER, I. TIMMERMANN-TROSIENER & R. SCHULTE-HERMANN. 1993. Peroxisomal enzyme induction uncoupled from enhanced DNA synthesis in putative preneoplastic foci of rats treated with a single dose of the peroxisome proliferator, nafenopin. Carcinogenesis 14: 2435-2437.
    • (1993) Carcinogenesis , vol.14 , pp. 2435-2437
    • Kraupp-Grasl, B.1    Huber, W.2    Timmermann-Trosiener, I.3    Schulte-Hermann, R.4
  • 74
    • 0027304198 scopus 로고
    • Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver
    • BARRASS, N. C., R. J. PRICE, B. G. LAKE & T. C. ORTON. 1993. Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver. Carcinogenesis 14: 1451-1456.
    • (1993) Carcinogenesis , vol.14 , pp. 1451-1456
    • Barrass, N.C.1    Price, R.J.2    Lake, B.G.3    Orton, T.C.4
  • 75
    • 0025816839 scopus 로고
    • Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: Comparison of WY-14,643 to clofibric acid, nafenopin and LY-171883
    • EACHO, P. I., P. L. LANIER & C. A. BRODHECKER. 1991. Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: Comparison of WY-14,643 to clofibric acid, nafenopin and LY-171883. Carcinogenesis 12: 1557-1561.
    • (1991) Carcinogenesis , vol.12 , pp. 1557-1561
    • Eacho, P.I.1    Lanier, P.L.2    Brodhecker, C.A.3
  • 76
    • 0018817695 scopus 로고
    • Adaptive responses of the liver to the gestagen and anti-androgen cyproterone acetate and other inducers. II. Induction of growth
    • SCHULTE-HERMANN, R., V. HOFFANN, W. PARZEFALL, M. KALLENBACH, A. GERHARDT & J. SCHUPPLER. 1980. Adaptive responses of the liver to the gestagen and anti-androgen cyproterone acetate and other inducers. II. Induction of growth. Chem.-Biol. Interact. 31: 287-300.
    • (1980) Chem.-Biol. Interact. , vol.31 , pp. 287-300
    • Schulte-Hermann, R.1    Hoffann, V.2    Parzefall, W.3    Kallenbach, M.4    Gerhardt, A.5    Schuppler, J.6
  • 78
    • 0028036895 scopus 로고
    • Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2
    • KRAJEWSKI, S., M. KRAJEWSKI, A. SHABAIK, H. G. WANG, T. MIYASHITA & J. C. REED. 1994. Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Am. J. Path 145: 1323-1336.
    • (1994) Am. J. Path , vol.145 , pp. 1323-1336
    • Krajewski, S.1    Krajewski, M.2    Shabaik, A.3    Wang, H.G.4    Miyashita, T.5    Reed, J.C.6
  • 79
    • 0025010196 scopus 로고
    • Nafenopin, a hypolipidemic and non-genotoxic hepatocarcinogen increases intracellular calcium and transiently decreases intracellular pH in hepatocytes without generation of inositol phos7 phates
    • OCHSNER, M., J. CREBA, J. WALKER, P. BENTLEY & S. MUAKASSAH-KELLY. 1990. Nafenopin, a hypolipidemic and non-genotoxic hepatocarcinogen increases intracellular calcium and transiently decreases intracellular pH in hepatocytes without generation of inositol phos7 phates. Biochem. Pharmacol. 40: 2247-2257.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 2247-2257
    • Ochsner, M.1    Creba, J.2    Walker, J.3    Bentley, P.4    Muakassah-Kelly, S.5
  • 80
    • 44949266149 scopus 로고
    • Cellular signalling in programmed cell death (apoptosis)
    • MCCONKEY, D. J., S. ORRENIUS & M. JONDAL. 1990. Cellular signalling in programmed cell death (apoptosis). Immunol. Today 11: 120-121.
    • (1990) Immunol. Today , vol.11 , pp. 120-121
    • Mcconkey, D.J.1    Orrenius, S.2    Jondal, M.3
  • 81
    • 0028013217 scopus 로고
    • Cytolysis mediated by ionophores and pore forming agents: Role of intracellular calcium in apoptosis
    • DUKE, R. C., R. Z. WITTER, P. S. NASH, J. D. E. YOUNG & D. M. OJICUS. 1994. Cytolysis mediated by ionophores and pore forming agents: Role of intracellular calcium in apoptosis. FASEB J. 8: 237-246.
    • (1994) FASEB J. , vol.8 , pp. 237-246
    • Duke, R.C.1    Witter, R.Z.2    Nash, P.S.3    Young, J.D.E.4    Ojicus, D.M.5
  • 83
    • 0026035011 scopus 로고
    • Activation and regulation of protein kinase C enzymes
    • NELSESTUAN, G. L. & M. D. BAZZI. 1991. Activation and regulation of protein kinase C enzymes. Bioenerget. Biomem. 23: 43-61.
    • (1991) Bioenerget. Biomem. , vol.23 , pp. 43-61
    • Nelsestuan, G.L.1    Bazzi, M.D.2
  • 85
    • 0025339442 scopus 로고
    • Palmitoyl-CoA and the acyl-CoA thioester of the carcinogenic peroxisome proliferator ciprofibrate potentiate diacylglycerol-activated protein kinase C by decreasing the phosphatidyl serine requirement of the enzyme
    • ORELLANA, A., P. C. HIDALGO, M. N. MORALES, D. MEZZANO & M. BRONFMAN. 1990. Palmitoyl-CoA and the acyl-CoA thioester of the carcinogenic peroxisome proliferator ciprofibrate potentiate diacylglycerol-activated protein kinase C by decreasing the phosphatidyl serine requirement of the enzyme. Eur. J. Biochem. 190: 57-61.
    • (1990) Eur. J. Biochem. , vol.190 , pp. 57-61
    • Orellana, A.1    Hidalgo, P.C.2    Morales, M.N.3    Mezzano, D.4    Bronfman, M.5
  • 86
    • 0026517976 scopus 로고
    • Involvement of calmodulin- and protein kinase C-related mechanism in an induction process of peroxisomal fatty acid oxidation-related enzymes by the hypolipidemic peroxisome proliferators
    • WATANABE, T., S. OKAWA, H. ITOGA, T. IMANAKA & T. SUGA. 1992. Involvement of calmodulin- and protein kinase C-related mechanism in an induction process of peroxisomal fatty acid oxidation-related enzymes by the hypolipidemic peroxisome proliferators. Biochem. Biophys. Acta. 1135: 84-90.
    • (1992) Biochem. Biophys. Acta. , vol.1135 , pp. 84-90
    • Watanabe, T.1    Okawa, S.2    Itoga, H.3    Imanaka, T.4    Suga, T.5
  • 87
    • 0007974412 scopus 로고
    • Mechanistic studies on the mitogenic response induced in hepatocytes by nafenopin, a non-mutagenic hepatocarcinogen
    • BIERI, F., F. WAECHTER, P. SAGELSDORFF, H. THOMAS & W. STAUBLI. 1991. Mechanistic studies on the mitogenic response induced in hepatocytes by nafenopin, a non-mutagenic hepatocarcinogen. Human and Exp. Toxicol 10: 86-87.
    • (1991) Human and Exp. Toxicol , vol.10 , pp. 86-87
    • Bieri, F.1    Waechter, F.2    Sagelsdorff, P.3    Thomas, H.4    Staubli, W.5
  • 88
    • 0027017178 scopus 로고
    • Induction of apoptosis - New targets for cancer chemotherapy
    • DIVE, C., C. A. EVANS & A. D. WHETTON. 1992. Induction of apoptosis - new targets for cancer chemotherapy. Semin. Cancer Biol. 3: 417-427.
    • (1992) Semin. Cancer Biol. , vol.3 , pp. 417-427
    • Dive, C.1    Evans, C.A.2    Whetton, A.D.3
  • 89
    • 0026794482 scopus 로고
    • Decreased protein kinase C activity is associated with programmed cell death (apoptosis) in freshly isolated rat hepatocytes
    • SANCHEZ, V., M. LUCAS, A. SANZ & R. GOBERNA. 1992. Decreased protein kinase C activity is associated with programmed cell death (apoptosis) in freshly isolated rat hepatocytes. Biosci. Rep. 12: 199-206.
    • (1992) Biosci. Rep. , vol.12 , pp. 199-206
    • Sanchez, V.1    Lucas, M.2    Sanz, A.3    Goberna, R.4
  • 90
    • 0027160338 scopus 로고
    • A study of protein kinase C isozyme distribution in relation to bcl-2 expression during apoptosis of epithelial cells in vivo
    • KNOX, K. A., G. D. JOHNSON & J. GORDON. 1993. A study of protein kinase C isozyme distribution in relation to bcl-2 expression during apoptosis of epithelial cells in vivo. Exp. Cell Res. 207: 68-73.
    • (1993) Exp. Cell Res. , vol.207 , pp. 68-73
    • Knox, K.A.1    Johnson, G.D.2    Gordon, J.3
  • 92
    • 0027160338 scopus 로고
    • A study of protein kinase C isozyme distribution in relation to Bcl-2 expression during apoptosis of epithelial cells in vivo
    • KORSMEYER, S. J., J. R. SHUTTER, D. J. VEIS, D. A. MERRY & Z. N. OLTVAI. 1993. A study of protein kinase C isozyme distribution in relation to Bcl-2 expression during apoptosis of epithelial cells in vivo. Exp. Cell Res. 207: 68-73.
    • (1993) Exp. Cell Res. , vol.207 , pp. 68-73
    • Korsmeyer, S.J.1    Shutter, J.R.2    Veis, D.J.3    Merry, D.A.4    Oltvai, Z.N.5
  • 93
    • 0027278522 scopus 로고
    • Positive regulation of the peroxisomal-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)
    • DREYER, C., H. KELLER, A. MAHFOUDI, V. LAUDET, G. KREY & W. WAHLI. 1993. Positive regulation of the peroxisomal-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol. Cell 77: 67-76.
    • (1993) Biol. Cell , vol.77 , pp. 67-76
    • Dreyer, C.1    Keller, H.2    Mahfoudi, A.3    Laudet, V.4    Krey, G.5    Wahli, W.6
  • 94
    • 0027749599 scopus 로고
    • Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver
    • ZHU, Y., K. ALVARES, Q. HUANG, M. S. RAO & J. K. REDDY. 1993. Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J. Biol. Chem. 268: 26817-26820.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26817-26820
    • Zhu, Y.1    Alvares, K.2    Huang, Q.3    Rao, M.S.4    Reddy, J.K.5
  • 95
    • 0027191040 scopus 로고
    • CDNA cloning, chromosomal mapping and functional characterisation of the human peroxisome proliferator-activated receptor
    • SHER, T., H. F. YI, W. MCBRIDE & F. J. GONZALEZ. 1993. CDNA cloning, chromosomal mapping and functional characterisation of the human peroxisome proliferator-activated receptor. Biochem. 32: 5598-5604.
    • (1993) Biochem. , vol.32 , pp. 5598-5604
    • Sher, T.1    Yi, H.F.2    Mcbride, W.3    Gonzalez, F.J.4
  • 97
    • 0027161015 scopus 로고
    • PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene
    • BARDOT, O., T. C. ALDRIDGE, N. LATRUFFE & S. GREEN. 1993. PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem. Biophys. Res. Commun. 192: 37-45.
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , pp. 37-45
    • Bardot, O.1    Aldridge, T.C.2    Latruffe, N.3    Green, S.4


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