Structure-function studies of peptides for cell adhesion inhibition: Identification of key residues by alanine mutation and peptide-truncation approach

Peptides

Volumn 28, Issue 8, 2007, Pages 1498-1508

  Li, Cheng ^a   Satyanarayanajois, Seetharama D ^b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF LOUISIANA AT MONROE   (United States)

Author keywords

Turn; Alanine mutation; CD2; CD2 CD58 interaction; Minimum inhibitory sequence

Indexed keywords

ALANINE; CD2 ANTIGEN; CYCLO(1,12)PENALANYLGLUTAMINYLPHENYLALANYLARGINYLLYSYLGLUTAMYLLYSYL GLUTAMYLTHREONYLPHENYLALANYLCYSTEINE; CYCLO(1,12)PENISOLEUCYLTYROSYLASPARTYLTHREONYLLYSYLGLYCYLLYSYL ASPARAGINYLVALYLLEUCYLCYSTEINE; CYCLO(1,12)PENVALYLTYROSYLSERYLTHREONYLASPARAGINYL GLYCYLTHREONYLARGINYLISOLEUCYLLEUCYLCYSTEINE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; BINDING KINETICS; BIOLOGICAL ACTIVITY; CELL ADHESION; CELL ASSAY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; MOLECULAR INTERACTION; MUTATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD2; ANTIGENS, CD58; CELL ADHESION; CELL LINE; CIRCULAR DICHROISM; HUMANS; JURKAT CELLS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 34547852483     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.07.003     Document Type: Article

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