Serum mannan-binding lectin levels in patients with celiac disease: An analysis of clinical and autoimmune features

Digestive Diseases and Sciences

Volumn 52, Issue 9, 2007, Pages 2145-2151

  De Carvalho, Elisandra Grangeiro ^a   Da Rosa Utiyama, Shirley Ramos ^a,d   Da Silva Kotze, Lorete Maria ^b   De Messias Reason, Iara Taborda ^a,c  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b HOSPITAL UNIVERSITÁRIO CAJURU   (Brazil)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d Laboratorio de Imunopatologia   (Brazil)

Author keywords

C reactive protein; Celiac disease; Complement system; Mannan binding lectin

Indexed keywords

C REACTIVE PROTEIN; IMMUNOGLOBULIN A; MANNAN BINDING LECTIN;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; CELIAC DISEASE; CHILD; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUTEN FREE DIET; HUMAN; IMMUNOFLUORESCENCE TEST; MAJOR CLINICAL STUDY; MALE; NEPHELOMETRY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; ANTIBODIES, ANTI-IDIOTYPIC; AUTOIMMUNITY; BIOLOGICAL MARKERS; BIOPSY; C-REACTIVE PROTEIN; CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOGLOBULIN A; INTESTINE, SMALL; MALE; MANNOSE-BINDING LECTIN; MIDDLE AGED; NEPHELOMETRY AND TURBIDIMETRY; PROGNOSIS; SEVERITY OF ILLNESS INDEX;

EID: 34547843592     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-007-9792-6     Document Type: Article

References (54)

1. Kirschfink M (1997) Controlling the complement system in inflammation. Immunopharmacology 38:51-62
2. Walport MJ (2001) Complement. First of two parts. N Engl J Med 344:1058-1066
3. Turner MW (1996) Mannose-binding lectin: the pluripotent molecule of the innate immune system. Immunol Today 17:532-540
4. Turner MW (2003) The role of mannose-binding lectin in health and disease. Mol Immunol 40:423-429
5. Ghiran I, Barbashov SF, Klickstein LB, Tas SW, Jensenius JC, Nicholson-Weller A (2000) Complement receptor 1/CD35 is a receptor for mannan-binding lectin. J Exp Med 192:1797-1808
6. Jack DL, Read RC, Tenner AJ, Frosch M, Turner MW, Klein NJ (2001) Mannose-binding lectin regulates the inflammatory response of human professional phagocytes to Neisseria meningitides serogroup B. J Infect Dis 184:1152-1162
7. Ogden CA, deCathelineau A, Hoffmann PR, Bratton D, Ghebrehiwet B, Fadok VA, Henson PM (2001) C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J Exp Med 194:781-795
8. Madsen HO, Garred P, Kurtzhals JAL, Lamm LU, Ryder LP, Thiel S, Svejgaard A (1994) A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding lectin. Immunogenetics 40:37-44
9. Eisen DP, Michinton RM (2003) Impact of mannose-binding lectin on susceptibility to infectious diseases. Clin Infect Dis 37:1496-1505
10. Rugonfalvi-kiss S, Endresz V, Madsen HO, Burian K, Duba J, Prohaszka Z, Karadi I, Romics L, Gonczol E, Fust G, Garred P (2002) Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin. Circulation 106:1071-1076
11. Schmiegelow K, Garred P, Lausen B, Andreassen B, Petersen BL, Madsen HO (2002) Increased frequency of mannose-binding lectin insufficiency among children with acute lymphoblastic leukemia. Blood 100:3757-3760
12. Christiansen OB, Kilpatrick DC, Souter V, Varming K, Thiel S, Jensenius JC (1999) Mannan-binding lectin deficiency is associated whit unexplained recurrent miscarriage. Scand J Immunol 49:193-196
13. Ambrosio AR, Messias-Reason IJ (2005) Leishmania (Viannia) braziliensis: interaction of mannose-binding lectin with surface glycoconjugates and complement activation. An antibody-independent defense mechanism. Parasite Immunol 27:333-340
14. Dornelles LN, Pereira-Ferrari L, Messias-Reason I (2006) Mannan-binding lectin plasma levels in leprosy: deficiency confers protection against the lepromatous but not the tuberculoid forms. Clin Exp Immunol 145:463-468
15. Bonar A, Chmiela M, Rozalska B (2004) Level of mannose-binding lectin (MBL) in patients with tuberculosis. Pneumonol Alergol Pol (Pneumonologia Polska) 72:201-205
16. Villarreal J, Crosdale D, Ollier W, Hajeer A, Thomson W, Ordi J, Balada E, Villardell M, The LS, Poulton K (2001) Mannose binding lectin and FCgammaRIIa (CD32) polymorphism in Spanish systemic lupus erythematosus patients. Rheumatology (Oxford) 40:1009-1012
17. Huang YF, Wang W, Han JY, Wu XW, Zhang ST, Liu CJ, Hu QG, Xiong P, Hamvas RM, Wood N, Gong FL, Bittles AH (2003) Increased frequency of the mannose-binding lectin LX haplotype in Chinese systemic lupus erythematosus patients. Eur J Immunogenet 30:121-124
18. Rector A, Lemey P, Laffut W, Keyaerts E, Struyf F, Wollants E, Vermeire S, Rutgeerts P, Van Ranst M (2001) Mannan-binding lectin (MBL2) gene polymorphisms in ulcerative colitis and Crohn's disease. Genes Immun 2:323-328
19. Seibold F, Konrad A, Flogerzi B, Seibold-Schmid B, Arni S, Jüliger S, Kun FJ (2004) Genetic variants of the mannan-binding lectin are associated with immune reactivity to mannans in Crohn's disease. Gastroenterology 127:1076-1084
20. Ip WK, Lau YL, Chan SY, Mok CC, Chan D, Tong KK, Lau CS (2000) Mannose-binding lectin and rheumatoid arthritis in southern Chinese. Arthritis Rheum 43:1679-1687
21. Saevarsdottir S, Vikingsdottir T, Vikingsson A, Manfredsdottir V, Geirsson AJ, Valdimarsson H (2001) Low mannose binding lectin predicts poor prognosis in patients with early rheumatoid arthritis. A prospective study. J Rheumatol 28:728-734
22. Tsutsumi A, Sasaki K, Wakamiya N, Ichikawa K, Atsumi T, Ohtani K, Suzuki Y, Koike T, Sumida T (2001) Mannose-binding lectin gene:polymorphisms in Japanese patients with systemic lupus erythematosus, rheumatoid arthritis and Sjogren's syndrome. Genes Immun 2:99-104
23. Wang ZY, Morinobu A, Kanagawa S, Kumagai S (2001) Polymorphism of the mannose binding lectin gene in patients with Sjogren's syndrome. Ann Rheum Dis 60:483-486
24. Ferguson A, Gillett H, Humphreys K, Kingstone K (1998) Heterogeneity of coeliac disease:clinical, pathological, immunological and genetic. Ann NY Acad Sci 859:112-120
25. Schuppan D (2000) Current concepts of celiac disease pathogenesis. Gastroenterology 119:234-242
26. da Rosa Utiyama SR, da Silva Kotze LM, de Messias Reason IT (2005) Complement factor B allotypes in the susceptibility and severity of coeliac disease in patients and relatives. Int J Immunogenet 32:307-314
27. Bai J, Zeballos E, Fried M, Corazza GR, Schuppan D, Farthing MJG, Catassi C, Greco L, Cohen H, Krabshuis JH (2005) Celiac disease. World Gastroenterol News 10(Suppl):1-8
28. Utiyama SRR, Kotze LMS, Nisihara RM, Carvalho RF, Carvalho EG, Sena MG, Reason IJTM (2001) Spectrum of autoantibodies in celiac patients and relatives. Dig Dis Sci 46:2624-2630
29. Hamer RJ (2005) Coeliac disease: background and biochemical aspects. Biotechnol Adv 23:401-408
30. da Silva Kotze LM, Nisihara RM, da Rosa Utiyama SR, Piovezan GC, Kotze LR (2006) Thyroid disorders in Brazilian patients with celiac disease. J Clin Gastroenterol 40:33-36
31. Gallagher RB, Kelly CP, Neville S, Sheils O, Weir DG, Feighery CF (1989) Complement activation within the coeliac small intestine is localized to Brunner's glands. Gut 30:1568-1573
32. Halstensen TS, Hvatum M, Scott H, Fausa O (1992) Association of subepithelial deposition of activated complement and immunoglobulin G and M response to gluten in coeliac disease. Gastroenterology 102:751-759
33. Unsworth DJ, Würzner R, Brown DR, Lachmann PJ (1993) Extracts of wheat gluten activate complement via the alternative pathway. Clin Exp Immunol 94:539-543
34. Boniotto M, Braida L, Spanò A, Pirulli D, Baldas V, Trevisiol C, Not T, Tommasini A, Amoroso A, Crovella S (2002) Variant mannose-binding lectin alleles are associated with celiac disease. Immunogenetics 54:596-598
35. Iltanen S, Mäki M, Collin P, Mustalahti K, Kaukinen K, Partanen J, Hulkkonen J, Hurme M, Aitoniemi J (2003) The association between mannan-binding lectin gene alleles and celiac disease. Am J Gastroenterol 98:2808-2809
36. Boniotto M, Braida L, Baldas V, Not T, Ventura A, Vatta S, Radillo O, Tedesco F, Percopo S, Montico M, Amoroso A, Crovella S (2005) Evidence of a correlation between mannose binding lectin and celiac disease: a model for other autoimmune diseases. J Mol Med 83:308-315
37. Petersen SV, Thiel S, Jensen L, Steffensen R, Jensenius JC (2001) An assay for the mannan-binding lectin pathway of complement activation. J Immunol Methods 257:107-116
38. Ladinser B, Rossipal E, Pittschieler K (1994) Endomysium antibodies in coeliac disease: an improved method. Gut 35:776-778
39. Rizzetto M, Swana G, Doniach D (1973) Microssomal antibodies in active chronic hepatitis and other disorders. Clin Exp Immunol 15:331-344
40. Bigazzi PE, Rose NR (1984) Pruebas para anticuerpos contra antigenos tissulares específicos. In: El Laboratorio en Inmunologia Clínica. Rose NR, Friedman H (eds). Editorial Medica Pan Americana, Buenos Aires, pp 968-979
41. Marsh MN (1992) Mucosal pathology in gluten sensitivity. In: Coeliac disease. Marsh MN (ed). Blackwell Scientific, Oxford, p 136
42. Steffensen R, Thiel S, Varming K, Jersild C, Jensenius JC (2000) Detection of structural gene mutations and promoter polymorphisms in the mannan-binding lectin (MBL) gene by polymerase chain reaction with sequence-specific primers. J Immunol Methods 241:33-42
43. Boniotto M, Radillo O, Braida L, Pirulli D, Citta A, not T, Amoroso A, Crovella S (2003) Detection of MBL-2 gene expression in intestinal biopsies of celiac patients by in situ reverse transcription polymerase chain reaction. Eur J Histochem 47:177-180
44. Schafrasnki MD, Stier A, Nisihara R, Messias-Reason IJ (2004) Significantly increased levels of mannose-binding lectin (MBL) in rheumatic heart disease: a beneficial role of MBL deficiency. Clin Exp Immunol 138:521-525
45. Inanc N, Mumeu G, Birtas E, Elbir Y, Yavuz S, Ergun T, Fresko I, Direskeneli H (2005) Serum mannan-binding lectin levels are decreased in behcet's disease and associated with disease severity. J Rheumatol 32:287-291
46. Suankratay C, Mold C, Zhang Y, Potempa LA, Lint TF, Gewurz H (1998) Complement regulation in innate immunity and the acute-phase response: inhibition of mannan-binding lectin-initiated complement cytolysis by C-reactive protein (CRP). Clin Exp Immunol 113:353-359
47. Kotze LMS (2006) Doença Celíaca. In: Tratado de Clínica Médica. Lopes AC, Neto A (eds). Editora Roca, São Paulo, pp 1036-1055
48. Kotze LMS, Utiyama SRR, Nisihara RM, Camargo VF, Ioshii SO (2003) IgA class anti-endomysial and anti-tissue transglutaminase antibodies in relation to duodenal mucosa changes in celiac disease. Pathology 35:56-60
49. Sategna-Guidetti C, Pulitano R, Grosso S, Ferfoglia G (1993) Serum IgA antiendomysium antibody titers as a marker of intestinal involvement and diet compliance in adult celiac sprue. J Clin Gastroenterol 17:123-127
50. Tursi A, Brandimarte G, Giorgetti G, Gigliobianco A, Lombardi D, Gasbarrini G (2001) Low prevalence of antigliadin and antiendomysium antibodies in subclinical/silent celiac disease. Am J Gastroenterol 96:1507-1510
51. Seibold F (2005) Food-induced immune responses as origin of bowel disease? Digestion 71:251-260
52. Vitoria JC, Castaño L, Rica I, Bilbao JR, Arrieta A, García-Masdevall MD (1998) Association of insulin-dependent diabetes mellitus and celiac disease: a study based on serologic markers. J Pediatr Gastroenterol Nutr 27:47-52
53. Toscano V, Conti FG, Anastasi E, Mariani P, Tiberti C, Poggi M, Montuori M, Monti S, Laureti S, Cipolletta E, Gemme G, Caiola S, Di Mario U, Bonamico M (2000) Importance of gluten in the induction of endocrine autoantibodies and organ dysfunction in adolescent celiac patients. Am J Gastroenterol 95:1742-1748
54. Saraheimo M, Forsblom C, Hansen TK, Teppo AM, Fagerudd J, Pettersson-Fernholm K, Thiel S, Tarnow L, Ebeling P, Flyvbjerg A, Groop PH (2005) Increased levels of mannan-binding lectin in type 1 diabetic patients with incipient and overt nephropathy. Diabetologia 48:198-202