Metabolic activation of herbicide products by Vicia faba detected in human peripheral lymphocytes using alkaline single cell gel electrophoresis

Toxicology in Vitro

Volumn 21, Issue 6, 2007, Pages 1143-1154

  Calderón Segura, María Elena ^a   Gómez Arroyo, Sandra ^a   Molina Alvarez, Bertha ^b   Villalobos Pietrini, Rafael ^a   Calderón Ezquerro, Carmen ^a   Cortés Eslava, Josefina ^a   Valencia Quintana, Pedro Rafael ^c   López González, Lucina ^a   Zúñiga Reyes, Rubén ^a   Sánchez Rincón, José ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b Laboratorio de Citogenética Humana   (Mexico)

^c CENTRO TLAXCALA DE BIOLOGÍA DE LA CONDUCTA   (Mexico)

Author keywords

Ametryn; Comet tail length; DNA damaged cells; EPTC herbicides; Human peripheral lymphocytes; In vivo Vicia faba metabolic activation; Metribuzin

Indexed keywords

AMETRYN; HERBICIDE; METRIBUZIN;

ARTICLE; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; LINEAR REGRESSION ANALYSIS; METABOLIC ACTIVATION; PERIPHERAL LYMPHOCYTE; PLANT ROOT; VICIA FABA;

BIOTRANSFORMATION; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; DNA DAMAGE; HERBICIDES; HUMANS; LYMPHOCYTES; MUTAGENS; PLANT EXTRACTS; PLANT ROOTS; THIOCARBAMATES; TRIAZINES; VICIA FABA;

LYCOPERSICON ESCULENTUM; SACCHARUM; TRITICUM AESTIVUM; VICIA FABA; ZEA MAYS;

EID: 34547838230     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.03.002     Document Type: Article

References (53)

1. Asongalem E.A., and Akintonwa A. Embryotoxic effects of oral ametryn exposure in pregnant rats. Bulletin of Environmental Contamination and Toxicology 58 (1997) 184-189
2. Baldwin A., Rogers H.J., Francis D., and Harwood J.L. Fatty acid elongation is important in the activity of thiocarbamate herbicides and in safening by dichlormid. Journal of Experimental Botany 54 (2003) 1289-1294
3. Bardalaye P.C., and Wheeler W.B. Gas chromatographic determination of ametryn and its metabolites in tropical roots crops. Analytical Chemistry 67 (1984) 280-284
4. Barret P.B., and Harwood J.L. Naphthalic anhydride prevents inhibition of fatty acid elongation by thiocarbamate. Phytochemistry 49 (1998) 1897-1903
5. Bayer de México. Tratamiento de la intoxicación por plaguicidas. Guía para Médicos (1994), Sector Agrochemicals Crop Protection Business Group, México pp. 1-84
6. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 (1976) 248-254
7. Calderón-Segura M.E., Gómez-Arroyo S., Villalobos-Pietrini R., and Espinosa-Ramírez M. In vivo and in vitro promutagen activation by Vicia faba of thiocarbamate herbicides molinate and butylate to products inducing sister chromatid exchanges in human lymphocyte cultures. Mutation Research 438 (1999) 81-88
8. Casida J.E., Kimmel E.C., Ohkawa H., and Ohkawa R. Sulfoxidation of thiocarbamate herbicides and metabolism of thiocarbamates sulfoxides in living mice and liver enzyme systems. Pesticide Biochemistry and Physiology 5 (1975) 1-11
9. Clements C., Ralph S., and Petras M. Genotoxicity of select herbicides in Rana catesbeiana tadpoles using the alkaline single-cell gel DNA electrophoresis (comet) assay. Environmental and Molecular Mutagenesis 29 (1997) 277-288
10. Coleman S., Linderman R., Hodgson E., and Rose R.L. Comparative Metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes. Environmental Health Perspectives 108 (2000) 1151-1157
11. Davies P.E., Cook L.S.J., and Geonarso D. Sublethal response to pesticides of several species of Australian freshwater fish and crustaceans and rainbow trout. Environmental Toxicology and Chemistry 13 (1994) 1341-1354
12. Edwards R., and Owen W.J. The comparative metabolism of the S-triazine herbicides atrazine and terbutryne in suspicions cultures of potato and weat. Pesticide Biochemistry and Physiology 34 (1989) 246-254
13. Fang J.L., and Vaca C.E. Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers. Carcinogenesis 18 (1997) 627-632
14. Farré M., Fernández J., Páez M., Granada L., Barba L., Gutiérrez H.M., Pulgarin C., and Barceló D. Analysis and toxicity of methomyl and ametryn after biodegration. Analytical and Bioanalytical Chemistry 373 (2002) 704-709
15. Flores-Maya S., Gómez-Arroyo S., Calderón-Segura M.E., Villalobos-Pietrini R., Waliszewski S.M., and Gómez de la Cruz L. Promutagen activation by Vicia faba of triazine herbicides metribuzin and ametryn through Vicia faba inducing sister chromatid exchanges in human peripheral lymphocyte cultures in vitro and in vivo Vicia faba root tip meristems. Toxicology In Vitro 19 (2005) 243-251
16. Frear D.S., Mansager E.R., Swanson H.R., and Tanaka F.S. Metribuzin metabolism in tomato: isolation and identification of N-g lucoside conjugates. Pesticide Biochemistry and Physiology 19 (1983) 270-281
17. Frear D.S., Swanson H.R., and Mansager E.R. Alternate pathways of metribuzin metabolism in soybean: formation of N-glucoside and homoglutathione conjugates. Pesticide Biochemistry and Physiology 23 (1985) 56-65
18. Gómez-Arroyo S., Calderón-Segura M.E., and Villalobos-Pietrini R. Sister chromatid exchange in human lymphocytes induced by propoxur following plant activation by Vicia faba. Environmental and Molecular Mutagenesis 26 (1995) 324-330
19. Gómez-Arroyo S., Calderón-Segura M.E., and Villalobos-Pietrini R. Biomonitoring of pesticides by plant metabolism: an assay based on the induction of sister-chromatid exchanges in human lymphocyte cultures by promutagen activation of Vicia faba. In: Butterworth F.M., Gunatilaka A., and Gonsebatt M.E. (Eds). Biomonitors and Biomarkers as Indicators of Environmental Change vol. 2 (2000), Plenum Press, New York 439-455
20. Hanioka N., Jinno H., Tanaka-Kagawa T., Nishimura T., and Ando M. In vitro of chlorotriazines: Characterization of simazine, atrazine, and propazine metabolism using liver microsomes from rats with various cytochrome P-450 inducers. Toxicology and Applied Pharmacology 156 (1999) 195-205
21. Hartmann A., and Speit G. The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay). Toxicology Letters 90 (1997) 183-188
22. Hartmann A., Kiskinis E., Fjallman A., and Suter W. Influence of cytotoxicity and compound precipitation on test results in the alkaline comet assay. Mutation Research 497 (2001) 199-212
23. Henderson L., Wolfreys A., Fedyk J., Bourner C., and Windebank S. The ability of the comet assay to discriminate between genotoxins and cytotoxins. Mutagenesis 13 (1998) 89-994
24. IARC, 2000. Triazines. Review.
25. Kaya B., Yanikoglu A., Creus A., and Marcos R. Genotoxicity testing of five herbicides in the Drosophila wing spot test. Mutation Research 465 (2000) 77-84
26. Kaya B., Marcos R., Yanikoglu A., and Creus A. Evaluation of the genotoxicity of four herbicides in the wing spot test of Drosophila melanogaster two different strains. Mutation Research 465 (2004) 77-84
27. Kligerman A.D., Doerr C.L., Tennant A.H., and Zucker R.M. Cytogenetic studies of three triazines herbicides I: In vitro studies. Mutation Research 465 (2000) 53-59
28. Kligerman A.D., Doerr C.L., Tennant A.H., and Peng B. Cytogenetic studies of three triazines herbicides II. In vivo micronucleus studies in mouse bone marrow. Mutation Research 47 (2000) 107-112
29. Kuroda K., Yamaguchi Y., and Endo G. Mitotic toxicity, sister chromatid exchange, and rec assay of pesticides. Archives of Environmental Contamination and Toxicology 23 (1992) 13-18
30. Lamoureux G.L., and Rusness D.G. EPTC. Mutagenic in corn, cotton and soybean: identification of a novel metabolite derived from the metabolism of glutathione conjugate. Journal Agricultural Food Chemistry 35 (1987) 1-7
31. Lang D.H., Criegee D., Grothusen A., Saalfrank R.W., and Bocker R.H. In vitro metabolism of atrazine, terbutylazine, ametryne and terbutryne in rats, pigs and humans. Drug Metabolism and Disposition 122 (1996) 27-37
32. Lang D.H., Rettie A.E., and Böcker R.H. Identification of enzimes involved in the metabolism of atrazine, terbuthylazine, ametryne and terbutryne in human liver microsomes. Chemistry Research and Toxicology 10 (1997) 1037-1044
33. Moretti M., Marcarelli M., Villarini M., Fatigoni C., Scassellati-Sforzolini G., and Pasquini R. In vitro testing for genotoxicity of the herbicide terbutryn: cytogenetic and primary DNA damage. Toxicology in Vitro 16 (2002) 81-88
34. Moriya M., Ohta T., Watanabe K., Miyazawa T., Kato K., and Shiraso Y. Futher mutagenicity studies on pesticides in bacterial reversion assay system. Mutation Research 116 (1983) 185-216
35. Obe G., Jonas R., and Schmidt S. Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: acetaldehyde not ethanol is mutagenic. Mutation Research 174 (1986) 47-51
36. Pauli B.D., Kent R.A., and Wong M.P. Canadian Water Quality Guidelines For Metribuzin (1990), Environmental Canada, Ottawa, Canada
37. Plewa M.J. Activation of chemical into mutagen by green plants: a preliminary discussion. Environmental and Health Perspectives 27 (1978) 45-50
38. Plewa M.J., and Gentile J.M. The activation of chemicals into mutagens by green plants. In: De Serres F.J., and Hollaender A. (Eds). Chemical Mutagens: Principles and Methods for their Detection vol. 7 (1982), Plenum Press, New York 401-420
39. Pöschl G., and Seitz H.K. Alcohol and cancer: review. Alcohol and Alcoholism 39 (2004) 155-165
40. Ribas G., Surrallés J., Carbonell E., Creus A., Xamena N., and Marcos R. Lack of genotoxicity of the herbicide atrazine in cultured human lymphocytes. Mutation Research 416 (1998) 93-99
41. Sandermann H. Plant metabolism of xenobiotics. Trends Biochemistry Science 17 (1992) 82-84
42. Singh N.P., McCoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantification of low levels of DNA damage in individual cells. Experimental Cell Research 17 (1988) 184-191
43. Smulders C.J., Bueters T.J., Van Kleef R.G., and Vijverberg H.P. Selective effects of carbamate pesticides on rat neural nicotinic acetylcholine and rat brain acetylcholinesterase. Toxicology and Applied Pharmacology 193 (2003) 139-146
44. Staub R.E., Sparks S.E., Gary B., Quistad G.B., and Casida J.E. S-methyl N-butylthiocarbamate sulfoxide. Selective carbamoylating agent for mouse mitochondrial aldehyde dehydrogenase. Biochemistry and Pharmacology 58 (1999) 1467-1473
45. Tadeo J.L., Sánchez-Brunete C., Pérez R.A., and Fernández M.D. Analysis of herbicides residues in cereals, fruits and vegetables. Chromatography 882 (2000) 175-195
46. Takehisa S., Kanaya N., and Rieger R. Promutagen activation by Vicia faba: an assay based on the induction of sister chromatid exchanges in Chinese hamster ovary cells. Mutation Research 197 (1988) 195-205
47. Tchounwoul P.B., Wilson B.I., Ransome R., Huang M.J., and Leszcynski J. Toxic assessment of atrazine and related triazine compounds in the microtox assay, and computational modeling for their structure-activity relationship. International Journal of Molecular Science 1 (2000) 63-74
48. Tennant A.H., Peng B., and Kligerman A.D. Genotoxicity studies of three triazine herbicides: in vivo studies using the alkaline single cell gel (SGC) assay. Mutation Research 493 (2001) 1-10
49. Tice R.R., Agurell E., Anderson D., Burlinson B., Hartmann A., Kobayashi H., Miyamae Y., Rojas E., Ryu J.C., and Sosaki Y.F. Single cell gel/comet Assay: guideline for in vitro and in vivo genetic toxicology testing. Environmental and Molecular Mutagenesis 35 (2000) 206-221
50. Venkat J.A., Shami S., Davis K., Plimmer J.R., Pfeil R., and Nair P.P. Relative genotoxic activities of pesticides evaluated by a modified SOS microplaque assay. Environmental and Molecular Mutagenesis 25 (1995) 67-76
51. Villarini M., Scassellati-Sforzolini G., Moretti M., and Pasquini R. In vitro genotoxicity of terbutryn evaluated by the alkaline single-cell microgel electrophoresis ́comet assay". Cell Biology and Toxicology 16 (2000) 285-292
52. Xu H.H., and Scurr K.M. Genotoxicity of 22 pesticides in the microtitration SOS chromotest. Toxicity Assessment 5 (1990) 1-14
53. Zimmerman L.J., Valentine H.S., and Valentine W.M. Charactization of S-(N-N-dialkylaminocarbonyl) cysteine adducts and enzyme inhibition produced by thiocarbamate herbicides in the rat. Chemical Research and Toxicology 17 (2004) 258-267