In vitro genotoxicity of terbutryn evaluated by the alkaline single-cell microgel-electrophoresis "comet" assay

Cell Biology and Toxicology

Volumn 16, Issue 5, 2000, Pages 285-292

  Villarini, M ^a   Scassellati Sforzolini, G ^a   Moretti, M ^a   Pasquini, R ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

"Comet" assay; Genotoxicity; Metabolic activation; Primary DNA damage; Terbutryn; Triazine herbicides

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; DIMETHYL SULFOXIDE; DRINKING WATER; HERBICIDE; TERBUTRYN; TRIAZINE DERIVATIVE;

ADULT; AGRICULTURE; ARTICLE; CEREAL; COMET ASSAY; CYTOTOXICITY; DNA DAMAGE; DRUG HALF LIFE; ECOSYSTEM; FOOD INDUSTRY; GEL ELECTROPHORESIS; GENOTOXICITY; GRASS; HUMAN; HUMAN CELL; LEACHING; LEGUME; LEUKOCYTE; LIVER HOMOGENATE; LIVER MICROSOME; MALE; NORMAL HUMAN; PH; PRIORITY JOURNAL;

ADULT; ANIMALS; DNA DAMAGE; ELECTROPHORESIS; GELS; HERBICIDES; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; RATS; TRIAZINES;

POACEAE;

EID: 0034526041     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026794213308     Document Type: Article

References (36)

1. In vitro studies of the metabolism of atrazine, simazine, and terbutryn in several vertebrate species
2. The single cell gel electrophoresis assay for induced DNA damage (comet assay): Measurement of tail length and moment
3. Studio del destino ambientale di alcuni presidi sanitari con particolare riferimento alle s-triazine, fenossiacidi e piretroidi artificiali
4. Triazine herbicide concentrations in the German Wadden sea
5. Cells of different tissues for in vitro and in vivo studies in toxicology: Compilation of isolation methods
6. Rapid biorecognition assay for herbicides in biological matrices
7. Enzyme immunoassays for striazines herbicides and their application in environmental and food analysis
8. The use of biological methods for pesticide monitoring
9. The concepts of tail moment and tail inertia in the single cell gel electrophoresis assay
10. Genotoxicity testing of five herbicides in the Drosophila wing spot test
11. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide
12. Isotachoforethic determination of herbicides prometryne, desmetryne, terbutryn and hydroxy-derivatives of atrazine and simazine in extracts of milk
13. Identification of enzymes involved in the metabolism of atrazine, terbuthylazine, ametryne, and terbutryne in human liver microsomes
14. Mass spectral characterization of the glucuronide conjugates of terbutryn (2-(t-butylamino)-4-(ethylamino)-6-methylthio)-s-triazine). Metabolites from rats and goats
15. Mutagenicity studies on 10 pesticides, on trichloroethane and on diaminobenzidine
16. Revised method for the Salmonella mutagenicity test
17. Extent of DNA damage in density-separated trout erythrocytes assessed by the 'comet' assay
18. Determination of terbutryn and its degradation products in water sediments, aquatic plants, and fish
19. Antialgal substances for iodine-disinfected swimming pools
20. Pollution potential of selected pesticides in soils
21. Herbicide cantamination of Mediterranean estuarine waters
22. Herbicide-induced DNA damage in human lymphocytes evaluated by the single-cell gel electrophoresis (SCGE) assay
23. Single cell gel electrophoresis assay: Methodology and applications
24. UV detection of triazine herbicides and their hydroxylated and dealkylated degradation products in well water
25. A simple technique for quantitation of low levels of DNA damage in individual cells
26. Analysis of triazine herbicides residues in butter and pasteurized milk
27. Enzyme-linked immunosorbent assay compared with gas chromatography/mass spectrometry for the determination of triazine herbicides in water
28. Genotoxicity to two triazine herbicides tested in the Drosophila wing spot and sex-linked recessive lethal tests
29. In vitro genotoxic effects of the insecticide deltamethrin in human peripheral blood leukocytes: DNA damage ('comet' assay) in relation to the induction of sister-chromatid exchanges and micronuclei