Cornichon regulates transport and secretion of TGFα-related proteins in metazoan cells

Journal of Cell Science

Volumn 120, Issue 14, 2007, Pages 2454-2466

  Perez Castro, Carolina ^a   Piscopo, Denise ^a   Nakagawa, Takatoshi ^a   Derynck, Rik ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cornichon; EGFR; Functional conversation; Secretion; Transport

Indexed keywords

CORNICHON; MEMBRANE PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HUMAN; IMMUNOPRECIPITATION; METAZOON; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN TRANSPORT; REGULATORY MECHANISM; YEAST;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DROSOPHILA; DROSOPHILA PROTEINS; EGG PROTEINS; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSFORMING GROWTH FACTOR ALPHA;

MAMMALIA; METAZOA;

EID: 34547793722     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.004200     Document Type: Article

References (39)

1. Bokel, C., Dass, S., Wilsch-Brauninger, M. and Roth, S. (2006). Drosophila Cornichon acts as cargo receptor for ER export of the TGFα-like growth factor Gurken. Development 133, 459-470.
2. Brachmann, C. B., Davies, A., Cost, G. J., Caputo, E., Li, J., Hieter, P. and Boeke, J. D. (1998). Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14, 115-132.
3. Brachmann R., Lindquist, P. B., Nagashima, M., Kohr, W., Lipari, T., Napier, M. and Derynck, R. (1989). Transmembrane TGFα precursors activate EGF/TGFα receptors. Cell 56, 691-700.
4. Bringman, T. S., Lindquist, P. B. and Derynck, R. (1987). Different transforming growth factor-alpha species are derived from a glycosylated and palmitoylated transmembrane precursor. Cell 48, 429-440.
5. Brown, C. L., Meise, K. S., Plowman, G. D., Coffey, R. J. and Dempsey, P. J. (1998). Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a metalloprotease inhibitor. Release of a predominant N-glycosylated 43-kDa soluble form. J. Biol. Chem. 273, 17258-17268.
6. Clemens, J. C., Worby, C. A., Simonson-Leff, N., Muda, M., Maehama, T., Hemmings, B. A. and Dixon, J. E. (2000). Use of doublr-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad Sci. USA 97, 6499-6503.
7. Derynck, R. (1992). The physiology of transforming growth factor-alpha. Adv. Cancer Res. 58, 27-52.
8. Fan, H. and Derynck, R. (1999). Ectodomain shedding of TGFα and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J. 18, 6962-6972.
9. Feng, X. H., Filvaroff, E. H. and Derynck, R. (1995). Transforming growth factor-beta (TGFβ)-induced down-regulation of cyclin A expression requires a functional TGFβ receptor complex. Characterization of chimeric and truncated type I and type II receptors. J. Biol. Chem. 270, 24237-24245.
10. Feng, X. H., Zhang, Y., Wu, R. Y. and Derynck, R. (1998). The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGFβ-induced transcriptional activation. Genes Dev. 12, 2153-2163.
11. Ghiglione, C., Bach, E. A., Paraiso, Y., Carraway, K. L., 3rd, Noselli, S. and Perrimon, N. (2002). Mechanism of activation of the Drosophila EGF receptor by the TGFα ligand Gurken during oogenesis. Development 129, 175-186.
12. Guichard, A., Roark, M., Ronshaugen, M. and Bier, E. (2000). brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling. Dev. Biol. 226, 255-266.
13. Hopper, N. A., Lee, J. and Sternberg, P. W. (2000). ARK-1 inhibits EGFR signaling in C. elegans. Mol. Cell 6, 65-75.
14. Kondylis, V. and Rabouille, C. (2003). A novel role for dpl 15 in the organization of tER sites in Drosophila. J. Cell Biol. 162, 185-198.
15. Kuo, A., Zhong, C., Lane, W. S. and Derynck, R. (2000). Transmembrane transforming growth factor-alpha tethers to the PDZ domain-containing, Golgi membrane-associated protein p59/GRASP55. EMBO J. 19, 6427-6439.
16. Lee, D. C., Fenton, S. E., Berkowitz, E. A. and Hissong, M. A. (1995). Transforming growth factor alpha: expression, regulation, and biological activities. Pharmacol. Rev. 47, 51-85.
17. Massague, J. and Pandiella, A. (1993). Membrane-anchored growth factors. Annu. Rev. Biochem. 62, 515-541.
18. McCaffery, J. M. and Farquhar, M. G. (1995). Localization of GTPases by indirect immunofluorescence and immunoelectron microscopy. Meth. Enzymol. 257, 259-279.
19. Nakagawa, T., Guichard, A., Castro, C. P., Xiao, Y., Rizen, M., Zhang, H. Z., Hu, D., Bang, A., Helms, J., Bier, E. et al. (2005). Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGFα family ligands. Dev. Dyn. 233, 1315-1331.
20. Neuman-Silberberg, F. S. and Schupbach, T. (1996). The Drosophila TGFalpha-like protein Gurken: expression and cellular localization during Drosophila oogenesis. Mech. Dev. 59, 105-113.
21. Perrimon, N. and Perkins, L. A. (1997). There must be 50 ways to rule the signal: the case of the Drsophila EGF receptor. Cell 89, 13-16.
22. Powers, J. and Barlowe, C. (1998). Transport of ax12p depends on erv14p, an ER-vesicle protein related to the Drosophila cornichon gene product. J. Cell Biol. 142, 1209-1222.
23. Powers, J. and Barlowe, C. (2002). Erv14p directs a transmembrane secretory protein into COPII-coated transport vesicles. Mol. Biol. Cell 13, 880-891.
24. Queenan, A. M., Barcelo, G., Van Buskirk, C. and Schupbach, T. (1999). The transmembrane region of Gurken is not required for biological activity, but is necessary for transport to the oocyte membrane in Drosophila. Mech. Dev. 89, 35-42.
25. Ray, R. P. and Schupbach, T. (1996). Intercellular signaling and the polarization of body axes during Drosophila oogenesis. Genes Dev. 10, 1711-1723.
26. Roth, S., Neuman-Silberberg, F. S., Barcelo, G. and Schupbach, T. (1995). cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila. Cell 81, 967-978.
27. Sabin, U., Weskamp, G., Kelly, K., Zhou, H. M., Higashiyama, S., Peschon, J., Hartmann, D., Saftig, P. and Blobel, C. P. (2004). Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J. Cell Biol. 164, 769-779.
28. Schlessinger, J. (2002). Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110, 669-672.
29. Schweitzer, R., Shaharabany, M., Seger, R. and Shilo, B. Z. (1995). Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev. 9, 1518-1529.
30. Shi, W., Fan, H., Shum, L. and Derynck, R. (2000). The tetraspanin CD9 associates with transmembrane TGFα and regulates TGFα-induced EGF receptor activation and cell proliferation. J. Cell Biol. 148, 591-602.
31. Shilo, B. Z. (2005). Regulating the dynamics of EGF receptor signaling in space and time. Development 132, 4017-4027.
32. Shum, L., Reeves, S. A., Kuo, A. C., Fromer, E. S. and Derynck, R. (1994). Association of the transmembrane TGFα precursor with a protein kinase complex. J. Cell Biol. 125, 903-916.
33. Sunnarborg, S. W., Hinkle, C. L., Stevenson, M., Russell, W. E., Raska, C. S., Peschon, J. J., Castner, B. J., Gerhart, M, J., Paxton, R. J., Black, R. A. et al. (2002). Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability. J. Biol. Chem. 277, 12838-12845.
34. Tsruya, R., Schlesinger, A., Reich, A., Gabay, L., Sapir, A. and Shilo, B. Z. (2002). Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz. Genes Dev. 16, 222-234.
35. Urban, S. and Freeman, M. (2002). Intramembrane protelysis controls diverse signalling pathways throughout evolution. Curr. Opin. Genet. Dev. 12, 512-518.
36. Urban, S., Lee, J. R. and Freeman, M. (2002). A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands. EMBO J. 21, 4277-4286.
37. Utku, N., Bulwin, G. C., Beinke, S., Heinemann, T., Beato, F., Randall, J., Schnieders B., Sandhoff, K., Volk, H. D., Milford, E. et al. (1999). The human homolog of Drosophila cornichon protein is differentially expressed in alloactivated T-cells. Biochim. Biophys. Acta 1449, 203-210.
38. Watson, P., Towney, A. K., Koko, P., Palmer, K. J. and Stephens, D. J. (2006). Sec 16 defines endoplasmic reticulum exit sites and is required for secretory cargo export in mammallian cells. Traffic 7, 1678-1687.
39. Zheng, Y. Schlondorff, J. and Blobel, C. P. (2002). Evidence for regulation ofthe tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1. J. Biol. Chem. 277, 42463-42470.