A new bioluminescent cellular assay to measure the transcriptional effects of chemicals that modulate the alpha-1 thyroid hormone receptor

Toxicology in Vitro

Volumn 21, Issue 6, 2007, Pages 1197-1205

  Jugan, M L ^a,b   Levy Bimbot M ^a   Pomerance M ^b,c   Tamisier Karolak, S ^a   Blondeau, J P ^a,b   Levi Y ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b INSERM   (France)

^c Universite Paris Sud   (France)

Author keywords

Endocrine disruptors; Environmental xenobiotics; In vitro bioassay; l Triiodothyronine; PC12 cell line; Reporter gene assay; TBBPA; Thyroid hormone receptor (TR)

Indexed keywords

2,4,6 TRIIODOPHENOL; 3,3',5,5' TETRABROMOBISPHENOL A; 3,3',5,5' TETRACHLOROBISPHENOL A; 4 HYDROXY 2',3,4',5,6' PENTACHLOROBIPHENYL; ENDOCRINE DISRUPTOR; HALOPHENOL; LIOTHYRONINE; LUCIFERASE; PENTACHLOROPHENOL; PHENOL DERIVATIVE; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR ALPHA1; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL CELL; ARTICLE; BIOLUMINESCENCE; CELL ASSAY; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME RELEASE; FOWL; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MODULATION; NONHUMAN; PROMOTER REGION; RAT; REPORTER GENE; REPRODUCIBILITY; SCREENING TEST; SIGNAL TRANSDUCTION; SIMIAN VIRUS 40; SUBTOTAL THYROIDECTOMY;

AVES; MAMMALIA;

EID: 34547775769     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.03.020     Document Type: Article

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