메뉴 건너뛰기




Volumn 12, Issue 5, 2007, Pages 695-703

Quadruple nucleoside therapy with zidovudine, lamivudine, abacavir and tenofovir in the treatment of HIV

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; EFAVIRENZ; LAMIVUDINE; NUCLEOSIDE ANALOG; RNA DIRECTED DNA POLYMERASE INHIBITOR; TENOFOVIR; ZIDOVUDINE;

EID: 34547749322     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (19)

References (76)
  • 1
    • 13844312888 scopus 로고    scopus 로고
    • German-Austrian recommendations for the antiretroviral therapy of HIV-infection (Status May 2004)
    • Salzberger B, Marcus U, Vielhaber B, et al. German-Austrian recommendations for the antiretroviral therapy of HIV-infection (Status May 2004). Eur J Med Res 2004; 9:491-504.
    • (2004) Eur J Med Res , vol.9 , pp. 491-504
    • Salzberger, B.1    Marcus, U.2    Vielhaber, B.3
  • 2
    • 33750999624 scopus 로고    scopus 로고
    • British HIV Association (BHIVA) guidelines for the treatment of HIV-infected adults with antiretroviral therapy (2006)
    • Gazzard B, Bernard AJ, Boffito M, et al. British HIV Association (BHIVA) guidelines for the treatment of HIV-infected adults with antiretroviral therapy (2006). HIV Med 2006; 7:487-503.
    • (2006) HIV Med , vol.7 , pp. 487-503
    • Gazzard, B.1    Bernard, A.J.2    Boffito, M.3
  • 3
    • 33747122666 scopus 로고    scopus 로고
    • Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel
    • Hammer SM, Saag MS, Schechter M, et al. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel. JAMA 2006; 296:827-843.
    • (2006) JAMA , vol.296 , pp. 827-843
    • Hammer, S.M.1    Saag, M.S.2    Schechter, M.3
  • 4
    • 0345012053 scopus 로고    scopus 로고
    • Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection
    • Robbins GK, De G, V, Shafer RW, et al. Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003; 349:2293-2303.
    • (2003) N Engl J Med , vol.349 , pp. 2293-2303
    • Robbins, G.K.1    De, G.V.2    Shafer, R.W.3
  • 5
    • 0344149561 scopus 로고    scopus 로고
    • Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection
    • Shafer RW, Smeaton LM, Robbins GK, et al. Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003; 349:2304-2315.
    • (2003) N Engl J Med , vol.349 , pp. 2304-2315
    • Shafer, R.W.1    Smeaton, L.M.2    Robbins, G.K.3
  • 6
    • 0038707454 scopus 로고    scopus 로고
    • Triple nucleoside combination zidovudine/lamivudine/abacavir versus zidovudine/lamivudine/ nelfinavir as first-line therapy in HIV-1-infected adults: A randomized trial
    • Matheron S, Descamps D, Boue F, et al. Triple nucleoside combination zidovudine/lamivudine/abacavir versus zidovudine/lamivudine/ nelfinavir as first-line therapy in HIV-1-infected adults: a randomized trial. Antivir Ther 2003; 8:163-171.
    • (2003) Antivir Ther , vol.8 , pp. 163-171
    • Matheron, S.1    Descamps, D.2    Boue, F.3
  • 7
    • 0035819909 scopus 로고    scopus 로고
    • Abacavir-lamivudine- zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial
    • Staszewski S, Keiser P, Montaner J, et al. Abacavir-lamivudine- zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: a randomized equivalence trial. JAMA 2001; 285:1155-1163.
    • (2001) JAMA , vol.285 , pp. 1155-1163
    • Staszewski, S.1    Keiser, P.2    Montaner, J.3
  • 8
    • 3242708850 scopus 로고    scopus 로고
    • Triple nucleoside treatment with abacavir plus the lamivudine/zidovudine combination tablet (COM) compared to indinavir/COM in antiretroviral therapy-naive adults: Results of a 48-week open-label, equivalence trial (CNA3014)
    • Vibhagool A, Cahn P, Schechter M, et al. Triple nucleoside treatment with abacavir plus the lamivudine/zidovudine combination tablet (COM) compared to indinavir/COM in antiretroviral therapy-naive adults: results of a 48-week open-label, equivalence trial (CNA3014). Curr Med Res Opin 2004; 20:1103-1114.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1103-1114
    • Vibhagool, A.1    Cahn, P.2    Schechter, M.3
  • 9
    • 2342537759 scopus 로고    scopus 로고
    • Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection
    • Gulick RM, Ribaudo HJ, Shikuma CM, et al. Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection. N Engl J Med 2004; 350:1850-1861.
    • (2004) N Engl J Med , vol.350 , pp. 1850-1861
    • Gulick, R.M.1    Ribaudo, H.J.2    Shikuma, C.M.3
  • 10
    • 3142682708 scopus 로고    scopus 로고
    • Poor virologic responses and early emergence of resistance in treatment naive, HIV-infected patients receiving a once daily triple nucleoside regimen of didanosine, lamivudine, and tenofovir DF
    • 8-11 February, San Francisco, CA, USA. Abstract 51
    • Jemsek J, Hutcherson P, Harper E. Poor virologic responses and early emergence of resistance in treatment naive, HIV-infected patients receiving a once daily triple nucleoside regimen of didanosine, lamivudine, and tenofovir DF. 11th Conference on Retroviruses and Opportunistic Infections. 8-11 February 2004, San Francisco, CA, USA. Abstract 51.
    • (2004) 11th Conference on Retroviruses and Opportunistic Infections
    • Jemsek, J.1    Hutcherson, P.2    Harper, E.3
  • 11
    • 22544472176 scopus 로고    scopus 로고
    • Comparative selection of the K65R and M184V/I mutations in human immunodeficiency virus type 1-infected patients enrolled in a trial of first-line triple-nucleoside analog therapy (Tonus IMEA 021)
    • Delaunay C, Brun-Vezinet F, Landman R, et al. Comparative selection of the K65R and M184V/I mutations in human immunodeficiency virus type 1-infected patients enrolled in a trial of first-line triple-nucleoside analog therapy (Tonus IMEA 021). J Virol 2005; 79:9572-9578.
    • (2005) J Virol , vol.79 , pp. 9572-9578
    • Delaunay, C.1    Brun-Vezinet, F.2    Landman, R.3
  • 12
    • 27944472569 scopus 로고    scopus 로고
    • Early virologic nonresponse to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive subjects
    • Gallant JE, Rodriguez AE, Weinberg WG, et al. Early virologic nonresponse to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive subjects. J Infect Dis 2005; 192:1921-1930.
    • (2005) J Infect Dis , vol.192 , pp. 1921-1930
    • Gallant, J.E.1    Rodriguez, A.E.2    Weinberg, W.G.3
  • 13
    • 16444373985 scopus 로고    scopus 로고
    • Early virologic failure in a pilot study evaluating the efficacy of therapy containing once-daily abacavir, lamivudine, and tenofovir DF in treatment-naive HIV-infected patients
    • Khanlou H, Yeh V, Guyer B, Farthing C. Early virologic failure in a pilot study evaluating the efficacy of therapy containing once-daily abacavir, lamivudine, and tenofovir DF in treatment-naive HIV-infected patients. AIDS Patient Care STDS 2005; 19:135-140.
    • (2005) AIDS Patient Care STDS , vol.19 , pp. 135-140
    • Khanlou, H.1    Yeh, V.2    Guyer, B.3    Farthing, C.4
  • 14
    • 33644766239 scopus 로고    scopus 로고
    • Early virologic failure and rescue therapy of tenofovir, abacavir, and lamivudine for initial treatment of HIV-1 infection: TONUS study
    • Landman R, Descamps D, Peytavin G, et al. Early virologic failure and rescue therapy of tenofovir, abacavir, and lamivudine for initial treatment of HIV-1 infection: TONUS study. HIV Clin Trials 2005; 6:291-301.
    • (2005) HIV Clin Trials , vol.6 , pp. 291-301
    • Landman, R.1    Descamps, D.2    Peytavin, G.3
  • 15
    • 33644511106 scopus 로고    scopus 로고
    • An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy
    • Moyle G, Higgs C, Teague A, et al. An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy. Antivir Ther 2006; 11:73-78.
    • (2006) Antivir Ther , vol.11 , pp. 73-78
    • Moyle, G.1    Higgs, C.2    Teague, A.3
  • 16
    • 0032551258 scopus 로고    scopus 로고
    • Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance
    • Carr A, Samaras K, Chisholm DJ, Cooper DA. Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance. Lancet 1998; 351:1881-1883.
    • (1998) Lancet , vol.351 , pp. 1881-1883
    • Carr, A.1    Samaras, K.2    Chisholm, D.J.3    Cooper, D.A.4
  • 17
    • 0032493043 scopus 로고    scopus 로고
    • A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
    • Carr A, Samaras K, Burton S, et al. A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors. AIDS 1998; 12:F51-F58.
    • (1998) AIDS , vol.12
    • Carr, A.1    Samaras, K.2    Burton, S.3
  • 19
    • 0034005969 scopus 로고    scopus 로고
    • Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection
    • Mulligan K, Grunfeld C, Tai VW, et al. Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection. J Acquir Immune Defic Syndr 2000; 23:35-43.
    • (2000) J Acquir Immune Defic Syndr , vol.23 , pp. 35-43
    • Mulligan, K.1    Grunfeld, C.2    Tai, V.W.3
  • 20
    • 0032558803 scopus 로고    scopus 로고
    • Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients
    • Walli R, Herfort O, Michl GM, et al. Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients. AIDS 1998; 12:F167-F173.
    • (1998) AIDS , vol.12
    • Walli, R.1    Herfort, O.2    Michl, G.M.3
  • 21
    • 24044474081 scopus 로고    scopus 로고
    • The management of HIV-1 protease inhibitor pharmacokinetic interactions
    • Winston A, Boffito M. The management of HIV-1 protease inhibitor pharmacokinetic interactions. J Antimicrob Chemother 2005; 56:1-5.
    • (2005) J Antimicrob Chemother , vol.56 , pp. 1-5
    • Winston, A.1    Boffito, M.2
  • 22
    • 0024310253 scopus 로고
    • Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
    • Larder BA, Kemp SD. Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 1989; 246:1155-1158.
    • (1989) Science , vol.246 , pp. 1155-1158
    • Larder, B.A.1    Kemp, S.D.2
  • 23
    • 0026565278 scopus 로고
    • Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
    • Kellam P, Boucher CA, Larder BA. Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. Proc Natl Acad Sci USA 1992; 89:1934-1938.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1934-1938
    • Kellam, P.1    Boucher, C.A.2    Larder, B.A.3
  • 24
    • 0029843986 scopus 로고    scopus 로고
    • Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility
    • Harrigan PR, Kinghorn I, Bloor S, et al. Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility. J Virol 1996; 70:5930-5934.
    • (1996) J Virol , vol.70 , pp. 5930-5934
    • Harrigan, P.R.1    Kinghorn, I.2    Bloor, S.3
  • 25
    • 10244227943 scopus 로고    scopus 로고
    • An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3′-azido-3′-deoxythymidine
    • Hooker DJ, Tachedjian G, Solomon AE, et al. An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3′-azido-3′-deoxythymidine. J Virol 1996; 70:8010-8018.
    • (1996) J Virol , vol.70 , pp. 8010-8018
    • Hooker, D.J.1    Tachedjian, G.2    Solomon, A.E.3
  • 26
    • 0027285372 scopus 로고
    • Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
    • Tisdale M, Kemp SD, Parry NR, Larder BA. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc Natl Acad Sci USA 1993; 90:5653-5656.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5653-5656
    • Tisdale, M.1    Kemp, S.D.2    Parry, N.R.3    Larder, B.A.4
  • 27
    • 0030945276 scopus 로고    scopus 로고
    • Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89
    • Tisdale M, Alnadaf T, Cousens D. Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89. Antimicrob Agents Chemother 1997; 41:1094-1098.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1094-1098
    • Tisdale, M.1    Alnadaf, T.2    Cousens, D.3
  • 28
    • 0034088720 scopus 로고    scopus 로고
    • Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group
    • Harrigan PR, Stone C, Griffin P, et al. Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group. J Infect Dis 2000; 181:912-920.
    • (2000) J Infect Dis , vol.181 , pp. 912-920
    • Harrigan, P.R.1    Stone, C.2    Griffin, P.3
  • 29
    • 0033995190 scopus 로고    scopus 로고
    • HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy
    • Miller V, Ait-Khaled M, Stone C, et al. HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy. AIDS 2000; 14:163-171.
    • (2000) AIDS , vol.14 , pp. 163-171
    • Miller, V.1    Ait-Khaled, M.2    Stone, C.3
  • 30
    • 0034069732 scopus 로고    scopus 로고
    • The role of abacavir (ABC, 1592) in antiretroviral therapy-experienced patients: Results from a randomized, double-blind, trial. CNA3002 European Study Team
    • Katlama C, Clotet B, Plettenberg A, et al. The role of abacavir (ABC, 1592) in antiretroviral therapy-experienced patients: results from a randomized, double-blind, trial. CNA3002 European Study Team. AIDS 2000; 14:781-789.
    • (2000) AIDS , vol.14 , pp. 781-789
    • Katlama, C.1    Clotet, B.2    Plettenberg, A.3
  • 31
    • 0033022106 scopus 로고    scopus 로고
    • Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development
    • Palmer S, Shafer RW, Merigan TC. Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development. AIDS 1999; 13:661-667.
    • (1999) AIDS , vol.13 , pp. 661-667
    • Palmer, S.1    Shafer, R.W.2    Merigan, T.C.3
  • 32
    • 20644436472 scopus 로고    scopus 로고
    • In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA
    • Wainberg MA, Miller MD, Quan Y, et al. In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA. Antivir Ther 1999; 4:87-94.
    • (1999) Antivir Ther , vol.4 , pp. 87-94
    • Wainberg, M.A.1    Miller, M.D.2    Quan, Y.3
  • 33
    • 1542327561 scopus 로고    scopus 로고
    • Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients
    • Miller MD, Margot N, Lu B, et al. Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients. J Infect Dis 2004; 189:837-846.
    • (2004) J Infect Dis , vol.189 , pp. 837-846
    • Miller, M.D.1    Margot, N.2    Lu, B.3
  • 34
    • 0036203532 scopus 로고    scopus 로고
    • Phenotypic susceptibilities to tenofovir in a large panel of clinically derived human immunodeficiency virus type 1 isolates
    • Harrigan PR, Miller MD, McKenna P, Brumme ZL, Larder BA. Phenotypic susceptibilities to tenofovir in a large panel of clinically derived human immunodeficiency virus type 1 isolates. Antimicrob Agents Chemother 2002; 46:1067-1072.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1067-1072
    • Harrigan, P.R.1    Miller, M.D.2    McKenna, P.3    Brumme, Z.L.4    Larder, B.A.5
  • 35
    • 0028273314 scopus 로고
    • Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations
    • Shafer RW, Kozal MJ, Winters MA, et al. Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations. J Infect Dis 1994; 169:722-729.
    • (1994) J Infect Dis , vol.169 , pp. 722-729
    • Shafer, R.W.1    Kozal, M.J.2    Winters, M.A.3
  • 36
    • 0028940084 scopus 로고
    • Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides
    • Shirasaka T, Kavlick MF, Ueno T, et al. Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides. Proc Natl Acad Sci USA 1995; 92:2398-2402.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2398-2402
    • Shirasaka, T.1    Kavlick, M.F.2    Ueno, T.3
  • 37
    • 0030048748 scopus 로고    scopus 로고
    • Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy
    • Iversen AK, Shafer RW, Wehrly K, et al. Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. J Virol 1996; 70:1086-1090.
    • (1996) J Virol , vol.70 , pp. 1086-1090
    • Iversen, A.K.1    Shafer, R.W.2    Wehrly, K.3
  • 38
    • 19244363136 scopus 로고    scopus 로고
    • Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain
    • Schmit JC, Cogniaux J, Hermans P, et al. Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain. J Infect Dis 1996; 174:962-968.
    • (1996) J Infect Dis , vol.174 , pp. 962-968
    • Schmit, J.C.1    Cogniaux, J.2    Hermans, P.3
  • 39
    • 0032533207 scopus 로고    scopus 로고
    • A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors
    • Winters MA, Coolley KL, Girard YA, et al. A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors. J Clin Invest 1998; 102:1769-1775.
    • (1998) J Clin Invest , vol.102 , pp. 1769-1775
    • Winters, M.A.1    Coolley, K.L.2    Girard, Y.A.3
  • 40
    • 0033552832 scopus 로고    scopus 로고
    • Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs
    • de Jong JJ, Goudsmit J, Lukashov VV, et al. Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs. AIDS 1999; 13:75-80.
    • (1999) AIDS , vol.13 , pp. 75-80
    • de Jong, J.J.1    Goudsmit, J.2    Lukashov, V.V.3
  • 41
    • 0032817241 scopus 로고    scopus 로고
    • A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance
    • Larder BA, Bloor S, Kemp SD, et al. A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance. Antimicrob Agents Chemother 1999; 43:1961-1967.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1961-1967
    • Larder, B.A.1    Bloor, S.2    Kemp, S.D.3
  • 43
    • 0025950055 scopus 로고
    • Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
    • St Clair MH, Martin JL, Tudor-Williams G, et al. Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 1991; 253:1557-1559.
    • (1991) Science , vol.253 , pp. 1557-1559
    • St Clair, M.H.1    Martin, J.L.2    Tudor-Williams, G.3
  • 44
    • 0029028067 scopus 로고
    • Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
    • Larder BA, Kemp SD, Harrigan PR. Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Science 1995; 269:696-699.
    • (1995) Science , vol.269 , pp. 696-699
    • Larder, B.A.1    Kemp, S.D.2    Harrigan, P.R.3
  • 45
    • 0032766314 scopus 로고    scopus 로고
    • Zidovudine resensitization and dual HIV-1 resistance to zidovudine and lamivudine in the delta lamivudine roll-over study
    • Masquelier B, Descamps D, Carriere I, et al. Zidovudine resensitization and dual HIV-1 resistance to zidovudine and lamivudine in the delta lamivudine roll-over study. Antivir Ther 1999; 4:69-77.
    • (1999) Antivir Ther , vol.4 , pp. 69-77
    • Masquelier, B.1    Descamps, D.2    Carriere, I.3
  • 46
    • 0037076708 scopus 로고    scopus 로고
    • Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF
    • Margot NA, Isaacson E, McGowan I, Cheng AK, Schooley RT, Miller MD. Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF. AIDS 2002; 16:1227-1235.
    • (2002) AIDS , vol.16 , pp. 1227-1235
    • Margot, N.A.1    Isaacson, E.2    McGowan, I.3    Cheng, A.K.4    Schooley, R.T.5    Miller, M.D.6
  • 47
    • 0142042463 scopus 로고    scopus 로고
    • Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates
    • Whitcomb JM, Parkin NT, Chappey C, Hellmann NS, Petropoulos CJ. Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates. J Infect Dis 2003; 188:992-1000.
    • (2003) J Infect Dis , vol.188 , pp. 992-1000
    • Whitcomb, J.M.1    Parkin, N.T.2    Chappey, C.3    Hellmann, N.S.4    Petropoulos, C.J.5
  • 48
    • 0033921632 scopus 로고    scopus 로고
    • In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-β-D- dioxolane-guanosine and suppress resistance to 3′-azido-3′- deoxythymidine
    • Bazmi HZ, Hammond JL, Cavalcanti SC, Chu CK, Schinazi RF, Mellors JW. In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-β-D- dioxolane-guanosine and suppress resistance to 3′-azido-3′- deoxythymidine. Antimicrob Agents Chemother 2000; 44:1783-1788.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1783-1788
    • Bazmi, H.Z.1    Hammond, J.L.2    Cavalcanti, S.C.3    Chu, C.K.4    Schinazi, R.F.5    Mellors, J.W.6
  • 49
    • 3042848853 scopus 로고    scopus 로고
    • Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: A 3-year randomized trial
    • Gallant IE, Staszewski S, Pozniak AL, et al. Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial. JAMA 2004; 292:191-201.
    • (2004) JAMA , vol.292 , pp. 191-201
    • Gallant, I.E.1    Staszewski, S.2    Pozniak, A.L.3
  • 50
    • 27544431950 scopus 로고    scopus 로고
    • A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT
    • White KL, Margot NA, Ly JK, et al. A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT. AIDS 2005; 19:1751-1760.
    • (2005) AIDS , vol.19 , pp. 1751-1760
    • White, K.L.1    Margot, N.A.2    Ly, J.K.3
  • 51
    • 0037118912 scopus 로고    scopus 로고
    • M184V is associated with a low incidence of thymidine analogue mutations and low phenotypic resistance to zidovudine and stavudine
    • Ait-Khaled M, Stone C, Amphlett G, et al. M184V is associated with a low incidence of thymidine analogue mutations and low phenotypic resistance to zidovudine and stavudine. AIDS 2002; 16:1686-1689.
    • (2002) AIDS , vol.16 , pp. 1686-1689
    • Ait-Khaled, M.1    Stone, C.2    Amphlett, G.3
  • 52
    • 33748052358 scopus 로고    scopus 로고
    • Antagonism between the HIV-1 reverse-transcriptase mutation K65R and thymidine-analogue mutations at the genomic level
    • Parikh UM, Barnas DC, Faruki H, Mellors JW. Antagonism between the HIV-1 reverse-transcriptase mutation K65R and thymidine-analogue mutations at the genomic level. J Infect Dis 2006; 194:651-660.
    • (2006) J Infect Dis , vol.194 , pp. 651-660
    • Parikh, U.M.1    Barnas, D.C.2    Faruki, H.3    Mellors, J.W.4
  • 53
    • 33646440592 scopus 로고    scopus 로고
    • The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations
    • Parikh UM, Bacheler L, Koontz D, Mellors JW. The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations. J Virol 2006; 80:4971-4977.
    • (2006) J Virol , vol.80 , pp. 4971-4977
    • Parikh, U.M.1    Bacheler, L.2    Koontz, D.3    Mellors, J.W.4
  • 54
    • 20244383737 scopus 로고    scopus 로고
    • Clonal analyses of HIV quasispecies in patients harbouring plasma genotype with K65R mutation associated with thymidine analogue mutations or L74V substitution
    • Wirden M, Malet I, Derache A, et al. Clonal analyses of HIV quasispecies in patients harbouring plasma genotype with K65R mutation associated with thymidine analogue mutations or L74V substitution. AIDS 2005; 19:630-632.
    • (2005) AIDS , vol.19 , pp. 630-632
    • Wirden, M.1    Malet, I.2    Derache, A.3
  • 55
    • 9244234943 scopus 로고    scopus 로고
    • Effect of concurrent zidovudine use on the resistance pathway selected by abacavir-containing regimens
    • Lanier ER, Givens N, Stone C, et al. Effect of concurrent zidovudine use on the resistance pathway selected by abacavir-containing regimens. HIV Medicine 2004; 5:394-399.
    • (2004) HIV Medicine , vol.5 , pp. 394-399
    • Lanier, E.R.1    Givens, N.2    Stone, C.3
  • 56
    • 7744219542 scopus 로고    scopus 로고
    • Predictors of selection of K65R: Tenofovir use and lack of thymidine analogue mutations
    • Valer L, Martin-Carbonero L, De Mendoza C, Corral A, Soriano V. Predictors of selection of K65R: tenofovir use and lack of thymidine analogue mutations. AIDS 2004; 18:2094-2096.
    • (2004) AIDS , vol.18 , pp. 2094-2096
    • Valer, L.1    Martin-Carbonero, L.2    De Mendoza, C.3    Corral, A.4    Soriano, V.5
  • 57
    • 2142657848 scopus 로고    scopus 로고
    • Which nucleoside and nucleotide backbone combinations select for the K65R mutation in HIV-1 reverse transcriptase
    • Winston A, Pozniak A, Mandalia S, Gazzard B, Pillay D, Nelson M. Which nucleoside and nucleotide backbone combinations select for the K65R mutation in HIV-1 reverse transcriptase. AIDS 2004; 18:949-951.
    • (2004) AIDS , vol.18 , pp. 949-951
    • Winston, A.1    Pozniak, A.2    Mandalia, S.3    Gazzard, B.4    Pillay, D.5    Nelson, M.6
  • 58
    • 20044390947 scopus 로고    scopus 로고
    • Resistance mutations before and after tenofovir regimen failure in HIV-1 infected patients
    • Wirden M, Marcelin AG, Simon A, et al. Resistance mutations before and after tenofovir regimen failure in HIV-1 infected patients. J Med Virol 2005; 76:297-301.
    • (2005) J Med Virol , vol.76 , pp. 297-301
    • Wirden, M.1    Marcelin, A.G.2    Simon, A.3
  • 59
    • 34547772466 scopus 로고    scopus 로고
    • Greiger-Zanlungo P, Rubin D, Blick G. Quadruple nucleoside reverse transcriptase inhibitor (NRTI) therapy with trizivir (TZV) and viread (TDF) in naive and experienced patients. 15th International AIDS Conference. 11-16 July 2004, Bangkok, Thailand. Poster TuPeB4513.
    • Greiger-Zanlungo P, Rubin D, Blick G. Quadruple nucleoside reverse transcriptase inhibitor (NRTI) therapy with trizivir (TZV) and viread (TDF) in naive and experienced patients. 15th International AIDS Conference. 11-16 July 2004, Bangkok, Thailand. Poster TuPeB4513.
  • 60
    • 30944468562 scopus 로고    scopus 로고
    • Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV
    • Gallant JE, DeJesus E, Arribas JR, et al. Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV. N Engl J Med 2006; 354:251-260.
    • (2006) N Engl J Med , vol.354 , pp. 251-260
    • Gallant, J.E.1    DeJesus, E.2    Arribas, J.R.3
  • 61
    • 33746706779 scopus 로고    scopus 로고
    • Eron J, Jr., Yeni P, Gathe J, Jr., et al. The KLEAN study of fosamprenavir-ritonavir versus lopinavir-ritonavir, each in combination with abacavir-lamivudine, for initial treatment of HIV infection over 48 weeks: a randomised non-inferiority trial. Lancet 2006; 368:476-482.
    • Eron J, Jr., Yeni P, Gathe J, Jr., et al. The KLEAN study of fosamprenavir-ritonavir versus lopinavir-ritonavir, each in combination with abacavir-lamivudine, for initial treatment of HIV infection over 48 weeks: a randomised non-inferiority trial. Lancet 2006; 368:476-482.
  • 62
    • 33847405664 scopus 로고    scopus 로고
    • Evolution of resistance mutations during low-level viral replication in HIV-1-infected patients treated with zidovudine/lamivudine/abacavir as a first-line regimen
    • Sturmer M, Dauer B, Moesch M, et al. Evolution of resistance mutations during low-level viral replication in HIV-1-infected patients treated with zidovudine/lamivudine/abacavir as a first-line regimen. Antivir Ther 2007; 12:25-30.
    • (2007) Antivir Ther , vol.12 , pp. 25-30
    • Sturmer, M.1    Dauer, B.2    Moesch, M.3
  • 63
    • 34547810719 scopus 로고    scopus 로고
    • Ruane P, Luber A, Gaultier C, et al. Efficacy of trizivir (TZV) and tenofovir (TDF) as HAART for HIV infected patients with current or underlying reverse transcriptase (RT) resistance. 15th International AIDS Conference. 11-16 July 2004, Bangkok, Thailand. Poster TuPeB4600.
    • Ruane P, Luber A, Gaultier C, et al. Efficacy of trizivir (TZV) and tenofovir (TDF) as HAART for HIV infected patients with current or underlying reverse transcriptase (RT) resistance. 15th International AIDS Conference. 11-16 July 2004, Bangkok, Thailand. Poster TuPeB4600.
  • 64
    • 20644434386 scopus 로고    scopus 로고
    • Switching from protease inhibitors to a single-class regimen of abacavir/lamivudine/zidovudine plus tenofovir in patients with HIV load suppression
    • d'Ettorre G, Mastroianni CM, Massetti AP, Lichtner M, D'Agostino C, Vullo V. Switching from protease inhibitors to a single-class regimen of abacavir/lamivudine/zidovudine plus tenofovir in patients with HIV load suppression. AIDS 2005; 19:841-842.
    • (2005) AIDS , vol.19 , pp. 841-842
    • d'Ettorre, G.1    Mastroianni, C.M.2    Massetti, A.P.3    Lichtner, M.4    D'Agostino, C.5    Vullo, V.6
  • 65
    • 34147095485 scopus 로고    scopus 로고
    • Intensification of a triple-nucleoside regimen with tenofovir or efavirenz in HIV-1-infected patients with virological suppression
    • Gulick RM, Lalama CM, Ribaudo HJ, et al. Intensification of a triple-nucleoside regimen with tenofovir or efavirenz in HIV-1-infected patients with virological suppression. AIDS 2007; 21:813-823.
    • (2007) AIDS , vol.21 , pp. 813-823
    • Gulick, R.M.1    Lalama, C.M.2    Ribaudo, H.J.3
  • 66
    • 17144414563 scopus 로고    scopus 로고
    • Efficacy of Tenofovir as intensification of zidovudine/lamivudine/abacavir fixed-dose combination in the treatment of HIV-positive patients
    • Khanlou H, Guyer B, Farthing C. Efficacy of Tenofovir as intensification of zidovudine/lamivudine/abacavir fixed-dose combination in the treatment of HIV-positive patients. J Acquir Immune Defic Syndr 2005; 38:627-628.
    • (2005) J Acquir Immune Defic Syndr , vol.38 , pp. 627-628
    • Khanlou, H.1    Guyer, B.2    Farthing, C.3
  • 67
    • 24044554243 scopus 로고    scopus 로고
    • Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol
    • Latham V, Stebbing J, Mandalia S, et al. Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol. J Antimicrob Chemother 2005; 56:186-189.
    • (2005) J Antimicrob Chemother , vol.56 , pp. 186-189
    • Latham, V.1    Stebbing, J.2    Mandalia, S.3
  • 68
    • 28944437873 scopus 로고    scopus 로고
    • Patients experiencing early virologic failure on a protease inhibitor- or nonnucleoside reverse transcriptase inhibitor-based initial regimen containing a thymidine analogue and Lamivudine can be successfully treated with a quadruple-nucleoside regimen
    • Rodriguez A, Hill-Zabala C, Sloan L, et al. Patients experiencing early virologic failure on a protease inhibitor- or nonnucleoside reverse transcriptase inhibitor-based initial regimen containing a thymidine analogue and Lamivudine can be successfully treated with a quadruple-nucleoside regimen. J Acquir Immune Defic Syndr 2006; 41:127-129.
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 127-129
    • Rodriguez, A.1    Hill-Zabala, C.2    Sloan, L.3
  • 69
    • 77950240918 scopus 로고    scopus 로고
    • Impact of different TAMs on outcome of a HAART regimen with ABC+3TC+AZT (Trizivir) and TDF
    • 29-31 March, Monte Carlo, Monaco. Poster 69
    • Berg T, Dupke S, Hintsche B, Mayr C, Schlote F. Impact of different TAMs on outcome of a HAART regimen with ABC+3TC+AZT (Trizivir) and TDF. 4th European Drug Resistance Workshop. 29-31 March 2006, Monte Carlo, Monaco. Poster 69.
    • (2006) 4th European Drug Resistance Workshop
    • Berg, T.1    Dupke, S.2    Hintsche, B.3    Mayr, C.4    Schlote, F.5
  • 70
    • 34547752780 scopus 로고    scopus 로고
    • Virologic Response to tenofovir DF (TDF) plus trizivir (TZV) therapy in heavily antiretroviral (ART)-experienced, HIV+ patients: 24 weeks results
    • 16-19 December, Washington, DC, USA. Abstract
    • Dauer B, Sturmer M, Muller A, et al. Virologic Response to tenofovir DF (TDF) plus trizivir (TZV) therapy in heavily antiretroviral (ART)-experienced, HIV+ patients: 24 weeks results. 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. 16-19 December 2005, Washington, DC, USA. Abstract H-520.
    • (2005) 45th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Dauer, B.1    Sturmer, M.2    Muller, A.3
  • 71
    • 0347364835 scopus 로고    scopus 로고
    • Change to abacavir-lamivudine-tenofovir combination treatment in patients with HIV-1 who had complete virological suppression
    • Hoogewerf M, Regez RM, Schouten WE, Weigel HM, Frissen PH, Brinkman K. Change to abacavir-lamivudine-tenofovir combination treatment in patients with HIV-1 who had complete virological suppression. Lancet 2003; 362:1979-1980.
    • (2003) Lancet , vol.362 , pp. 1979-1980
    • Hoogewerf, M.1    Regez, R.M.2    Schouten, W.E.3    Weigel, H.M.4    Frissen, P.H.5    Brinkman, K.6
  • 72
    • 17844391588 scopus 로고    scopus 로고
    • High virological failure rate in HIV patients after switching to a regimen with two nucleoside reverse transcriptase inhibitors plus tenofovir
    • Perez-Elias MJ, Moreno S, Gutierrez C, et al. High virological failure rate in HIV patients after switching to a regimen with two nucleoside reverse transcriptase inhibitors plus tenofovir. AIDS 2005; 19:695-698.
    • (2005) AIDS , vol.19 , pp. 695-698
    • Perez-Elias, M.J.1    Moreno, S.2    Gutierrez, C.3
  • 73
    • 20844434101 scopus 로고    scopus 로고
    • Early virologic response at 1 month, and 8 months median follow-up, of a New Triple NUCS combination (zidovudine, lamivudine and tenofovir) in 42 antiretroviral naïve, HIV-1 infected patients
    • 22-25 February, Boston, MA, USA. Abstract 599
    • Rey D, Krebs M, Partisani M, et al. Early virologic response at 1 month, and 8 months median follow-up, of a New Triple NUCS combination (zidovudine, lamivudine and tenofovir) in 42 antiretroviral naïve, HIV-1 infected patients. 12th Conference on Retroviruses and Opportunistic Infections. 22-25 February 2005, Boston, MA, USA. Abstract 599.
    • (2005) 12th Conference on Retroviruses and Opportunistic Infections
    • Rey, D.1    Krebs, M.2    Partisani, M.3
  • 74
    • 33744495252 scopus 로고    scopus 로고
    • Twenty-four-week efficacy and resistance profile of a zidovudine/lamivudine/tenofovir DF combination therapy in antiretroviral-naive patients
    • Masquelier B, Neau D, Boucher S, et al. Twenty-four-week efficacy and resistance profile of a zidovudine/lamivudine/tenofovir DF combination therapy in antiretroviral-naive patients. Antiviral Therapy 2005; 10:S22-S22.
    • (2005) Antiviral Therapy , vol.10
    • Masquelier, B.1    Neau, D.2    Boucher, S.3
  • 75
    • 33745450105 scopus 로고    scopus 로고
    • Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa
    • DART Virology Group and Trial Team
    • DART Virology Group and Trial Team. Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa. AIDS 2006; 20:1391-1399.
    • (2006) AIDS , vol.20 , pp. 1391-1399
  • 76
    • 12144282312 scopus 로고    scopus 로고
    • Low rate of treatment failure on antiretroviral therapy with tenofovir, lamivudine and zidovudine
    • Mauss S, Milinkovic A, Hoffmann C, et al. Low rate of treatment failure on antiretroviral therapy with tenofovir, lamivudine and zidovudine. AIDS 2005; 19:101-102.
    • (2005) AIDS , vol.19 , pp. 101-102
    • Mauss, S.1    Milinkovic, A.2    Hoffmann, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.