Effect of essential oils and isolated compounds from Pimpinella species on NF-κB: A target for antiinflammatory therapy

Phytotherapy Research

Volumn 21, Issue 8, 2007, Pages 741-745

  Tabanca, Nurhayat ^a   Ma, Guoyi ^b   Pasco, David S ^a,b   Bedir, Erdal ^c   Kirimer, Nese ^d   Baser, K Husnu Can ^d   Khan, Ikhlas A ^a,b   Khan, Shabana I ^b,e  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c EGE UNIVERSITY   (Turkey)

^d ANADOLU UNIVERSITY   (Turkey)

^e UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Essential oil; NF B mediated transcription; Phenylpropanoid; Pimpinella species

Indexed keywords

2 METHOXY 2 (3 METHYLOXIRANYL)PHENYLISOBUTYRATE; 4 (2 PROPENYL)PHENYLANGELATE; 4 (3 METHYLOXIRANYL)PHENYLTIGLATE; 4 METHOXY 2 (3 METHOXIRANYL)PHENYLANGELATE; ANISE OIL; EPOXY PSEUDOISOEUGENOL 2 METHYLBUTYRATE; ESSENTIAL OIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PIMPINELLA CORYMBOSA EXTRACT; PIMPINELLA RHODANTA EXTRACT; PIMPINELLA TRAGIUM EXTRACT; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANISE; ARTICLE; CANCER CELL CULTURE; DRUG ISOLATION; HUMAN; HUMAN CELL; IC 50; INFLAMMATION; NONHUMAN; PIMPINELLA CORYMBOSA; PIMPINELLA RHODANTA; PIMPINELLA TRAGIUM; PLANT ROOT; SPECIES DIFFERENCE; TRANSCRIPTION REGULATION; VERO CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CERCOPITHECUS AETHIOPS; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR STRUCTURE; NF-KAPPA B; OILS, VOLATILE; PHYTOTHERAPY; PIMPINELLA; PLANT COMPONENTS, AERIAL; PLANT OILS; PLANT ROOTS; SPECIES SPECIFICITY;

MAMMALIA; PIMPINELLA; PIMPINELLA CORYMBOSA; PIMPINELLA TRAGIUM;

EID: 34547702251     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2154     Document Type: Article

References (18)

1. Baldwin AS. 1996. The NF-kappa B and I kappa B proteins: New discoveries and insights. Annu Rev Immunol 14: 649-681.
2. Baser KHC. 1997. Tibbi ve Aromatik Bitkilerin ilac ve Alkollu icki Sanayinde Kullanimi. Istanbul Ticaret Odasi Yayinlari: Istanbul, Turkey, 33-35.
3. th International Symposium on Natural Product Chemistry, 18-22 January 2000, Karachi, Pakistan. HEJ: Karachi, 271-289.
4. Bottini AT, Dev V, Garfagnoli DJ et al. 1986. Oxiranylphenyl esters from Pimpinella diversifolia. Phytochemistry 25: 207-211.
5. Bremner P, Tang S, Birkmayer H et al. 2004. Phenylpropanoid NF-κB inhibitors from Bupleurum fruticosum. Planta Med 70: 914-918.
6. Diaz AM, Abad MJ, Fernandez L, Silvan AM, De Santos J, Bermejo P. 2004. Phenylpropanoid glycosides from Scrophularia scorodonia: In vitro anti-inflammatory activity. Life Sci 74: 2515-2526.
7. Kubeczka KH. 1997. The essential oil composition of Pimpinella species. In The 28th International Symposium on Essential Oils, Proceedings, Baser KHC, Kirimer N. (eds), 1-3 September, Anadolu University Press: Eskisehir, Turkey, 35-56.
8. Ma G, Khan SI, Benavides G et al. 2006. Inhibition of NF-κB mediated transcription and induction of apoptosis by melampolides and repandolides. Cancer Chemother Pharmacol (in press). DOI: 10.1007/s00280-006-0344-0.
9. Nagaraju N, Rao KN. 1990. A survey of plant crude drugs of India. J Ethnopharmacol 29: 137-158.
10. Rayyan Y, Williams J, Rigas B. 2002. The role of NSAIDs in the prevention of colon cancer. Cancer Invest 7-8: 1002-1011.
11. Sahpaz S, Garbacki N, Tits M, Bailleul F. 2002. Isolation and pharmacological activity of phenylpropanoid esters from Marrubium vulgare. J Ethnopharmacol 79: 389-392.
12. Scaife CL, Kuang J, Wills JC et al. 2002. Nuclear factor κB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis. Cancer Res 62: 6870-6878.
13. Tabanca N, Bedir E, Ferraira D et al. 2005a. Bioactive constituents from Pimpinella Species growing in Turkey. Chem Biodiv 2: 221-232.
14. Tabanca N, Bedir E, Kirimer N et al. 2003. Antimicrobial compounds from Pimpinella species growing in Turkey. Planta Med 69: 933-938.
15. Tabanca N, Douglas AW, Bedir E et al. 2005b. Patterns of essential oil relationships in Pimpinella (Umbelliferae) based on phylogenetic relationships using nuclear and chloroplast sequences. Plant Genet Resour 3: 149-169.
16. Tabanca N, Khan SI, Bedir E et al. 2004. Estrogenic activity of isolated compounds and essential oils of Pimpinella species from Turkey, evaluated using a recombinant yeast screen. Planta Med 70: 728-735.
17. Wulczyn FG, Krappmann D, Scheidereit C. 1996. The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammation. J Mol Med 74: 749-769.
18. Yin MJ, Yamamoto J, Gaynor RB. 1998. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I κB kinase-B. Nature 396: 77-80.