Estrogenic activity of isolated compounds and essential oils of Pimpinella species from Turkey, evaluated using a recombinant yeast screen

Planta Medica

Volumn 70, Issue 8, 2004, Pages 728-735

  Tabanca, Nurhayat ^a,b   Khan, Shabana I ^b,e   Bedir, Erdal ^b,d   Annavarapu, Srinivas ^c   Willett, Kristine ^c   Khan, Ikhlas A ^b,c   Kirimer, Nese ^a   Baser, K Husnu Can ^a  

^a ANADOLU UNIVERSITY   (Turkey)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c UNIVERSITY OF MISSISSIPPI   (United States)

^d EGE UNIVERSITY   (Turkey)

^e UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

(E) anethole; Apiaceae; Essential oil, GC and GC MS; Estrogenic activity; Phenylpropanoid; Pimpinella species

Indexed keywords

2,4 DIMETHOXYPROPENYLBENZENE ISOOSMORHIZOLE; 4 (1 PROPENYL)PHENYL TIGLATE; 4 (2 PROPENYL)PHENYL ANGELATE; 4 CYMENE; 4 METHOXY 2 (3 METHYLOXIRANYL)PHENYL ISOBUTYRATE; ALPHA ZINGIBERENE; ANETHOLE; ANISE OIL; BETA BERGAMOTENE; BETA BISABOLENE; BETA EUDESMOL; BETA FARNESENE; BETA PINENE; CARYOPHYLLENE; EPOXYPSEUDOISOEUGENOL 2 METHYLBUTYRATE; ESSENTIAL OIL; ESTRADIOL; GAMMA HIMACHALENE; GEIJERENE; GERMACRENE D; ISOOSMORHIZOLE; LIMONENE; O METHYLCHAVICOL; O METHYLEUGENOL; PIMPINELLA EXTRACT; PINENE; PLANT EXTRACT; SABINENE; TERPINENE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANISE; ARTICLE; ESTROGEN ACTIVITY; MEDICINAL PLANT; NONHUMAN; PIMPINELLA ANISETUM; PIMPINELLA AUREA; PIMPINELLA FLABELLIFOLIA; PIMPINELLA ISAURICA; PIMPINELLA NUDICAULIS; PIMPINELLA PEREGRINA; PIMPINELLA PEUCEDANIFOLIA; PIMPINELLA PUBERULA; PIMPINELLA RHODANTHA; PIMPINELLA TRAGIUM; TURKEY (REPUBLIC); YEAST;

DOSE-RESPONSE RELATIONSHIP, DRUG; FRUIT; HUMANS; ISOFLAVONES; PHYTOESTROGENS; PHYTOTHERAPY; PIMPINELLA; PLANT COMPONENTS, AERIAL; PLANT OILS; PLANT PREPARATIONS; PLANT ROOTS; SACCHAROMYCES CEREVISIAE;

APIACEAE; MYRRHIS ODORATA; PEREGRINA; PIMPINELLA; PIMPINELLA ANISETUM; PIMPINELLA AUREA; PIMPINELLA FLABELLIFOLIA; PIMPINELLA ISAURICA; PIMPINELLA NUDICAULIS; PIMPINELLA PEREGRINA; PIMPINELLA PEUCEDANIFOLIA; PIMPINELLA PUBERULA; PIMPINELLA RHODANTHA; PIMPINELLA TRAGIUM;

EID: 4444263408     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-827203     Document Type: Article

References (21)

1. Howes MJ, Houghton PJ, Barlow DJ, Pocock VJ, Milligan SR. Assessment of estrogenic activity in some common essential oil constituents. J Pharm Pharmacol 2002; 54: 1521-8
2. Diel P, Smolnikar K, Michna H. In vitro test systems for the evaluation of the estrogenic activity of natural products. Planta Medica 1999; 65: 197-203
3. Dhar SK. Antifertility activity and hormonal profile of trans-anethole in rats. Indian J Physiol Pharmacol 1995; 39: 63-7
4. Setchell KDR, Cassidy A. Dietary isoflavones: biological effects and relevance to human health. J Nutr 1999; 129: 758-67
5. Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KPL, Booth N, Constantinou AI, Pezzuto JM, Fong HHS, Farnsworth NR, Bolton JL. Evolution of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem 2001; 49: 2472-9
6. Kurzer MS, Xu X. Dietary phytoestrogens. Ann Rev Nutr 1997; 17: 353-81
7. Cosman F, Lindsay R. Selective estrogen receptor modulators: clinical spectrum. Endocr Rev 1999; 20: 418-34
8. Sainer AG, Amat L, Carbo-Dorca R, Schultz TW, Cronin MTD. Molecular quantum similarity analysis of estrogenic activity. J Chem Inf Comput Sci 2003; 43: 166-76
9. Morton MS, Arisaka O, Miyake N, Morgan LD, Evans BA. Phytoestrogen concentrations in serum from Japanese men and women over forty years of age. J Nutr 2002; 132: 3168-71
10. Davis PH. Flora of Turkey and East Aegean Islands; vol. 4 University Press, Edinburgh: 1972: pp 352-64
11. Albert-Puleo M. Fennel and anise as estrogenic agents. J Ethnopharmacol 1980; 2: 337-44
12. Duke JA. Handbook of medicinal herbs. CRC Press, London: 1985: pp 374-5
13. Santos PM, Figueireido AC, Oliveira MM, Barroso JG, Pedro LG, Deans SG, Younus AKM, Scheffer JC. Morphological stability of Pimpinella anisum hairy root cultures and time-course study of their essential oils. Biotech Lett 1999; 21: 859-64
14. Santos PM, Figueirdo AC, Oliveira MM, Barroso JG, Pedro LG, Deans SG, Younus AKM, Scheffer JC. Essential oils from hairy root cultures and from fruits and roots of Pimpinella anisum. Phytochemistry 1998; 48: 455-60
15. Routledge EJ, Sumpter JP. Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen. Environ Toxicol Chem 1996; 15: 241-8
16. Kleiman R, Plattner DR, Weisleder D. Antigermination of phenylpropanoids from the genus Pimpinella. J Nat Prod 1988; 52: 249-56
17. Tabanca N, Bedir E, Kirimer N, Baser KHC, Khan SI, Jacob MR, Khan IA. Antimicrobial compounds from Pimpinella species growing in Turkey. Planta Medica 2003; 69: 933-8
18. Kubeczka KH, Bartsch A, Ullmann I. Recent Investigations of essential oils of Apiaceae. In: Aetherísche Oele, Kubeczka KH (editor). George Thieme Verlag, Stuttgart: 1982: pp 158-87
19. Markiewicz L, Garey J, Adlercreutz H, Gurpide E. In vitro bioassays of non-steriodal phytoestrogens. J Steroid Biochem Mol 1993; 45: 399-405
20. Collins BM, McLachlan JA, Arnold SF. The estrogenic and antiestrogenic activities of phytochemicals with human estrogen receptor expressed in yeast. Steroids 1997; 62: 365-72
21. Milligan SR, Balasubramanian AV, Kalita JC. Relative potency of xenobiotic estrogens in an acute in vivo, mammalian assay. Environ Health Perspect 1998; 106: 23-26