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Volumn 67, Issue 11, 2007, Pages 1152-1162

Androgen receptor or estrogen receptor-β blockade alters DHEA-, DHT-, and E2-induced proliferation and PSA production in human prostate cancer cells

Author keywords

AR; Casodex; DHEA; DHT; E2; ER ; ICI 182,780; PSA

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; BICALUTAMIDE; ESTRADIOL; ESTROGEN RECEPTOR BETA; FULVESTRANT; MESSENGER RNA; METRIBOLONE; PRASTERONE; PROSTATE SPECIFIC ANTIGEN; SMALL INTERFERING RNA;

EID: 34547700033     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20585     Document Type: Article
Times cited : (49)

References (39)
  • 1
    • 79955715818 scopus 로고    scopus 로고
    • Alesci S, Manoli I, Blackman MR. Dehydrodepiandrosterone (DHEA). In: Coates P, Blackman MR, Cragg G, Levine M, Moss J, White J, editors. Encyclopedia of dietary supplements, 1st ed. New York, NY: Marcel Dekker, Inc.; 2005:167-176.
    • Alesci S, Manoli I, Blackman MR. Dehydrodepiandrosterone (DHEA). In: Coates P, Blackman MR, Cragg G, Levine M, Moss J, White J, editors. Encyclopedia of dietary supplements, 1st ed. New York, NY: Marcel Dekker, Inc.; 2005:167-176.
  • 2
    • 13844262629 scopus 로고    scopus 로고
    • Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells
    • Arnold JT, Le H, McFann KK, Blackman MR. Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells. Am J Physiol Endocrinol Metab 2005; 288(3):E573-E584.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , Issue.3
    • Arnold, J.T.1    Le, H.2    McFann, K.K.3    Blackman, M.R.4
  • 3
    • 0026562430 scopus 로고
    • The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens
    • Veldscholte J, Berrevoets CA, Ris-Stalpers C, Kuiper GG, Jenster G, Trapman J, Brinkmann AO, Mulder E. The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens. J Steroid Biochem Mol Biol 1992;41(3-8):665-669.
    • (1992) J Steroid Biochem Mol Biol , vol.41 , Issue.3-8 , pp. 665-669
    • Veldscholte, J.1    Berrevoets, C.A.2    Ris-Stalpers, C.3    Kuiper, G.G.4    Jenster, G.5    Trapman, J.6    Brinkmann, A.O.7    Mulder, E.8
  • 5
    • 0034126666 scopus 로고    scopus 로고
    • Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: Regulation by methylation and involvement in growth regulation
    • Lau KM, LaSpina M, Long J, Ho SM. Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: Regulation by methylation and involvement in growth regulation. Cancer Res 2000;60(12):3175-3182.
    • (2000) Cancer Res , vol.60 , Issue.12 , pp. 3175-3182
    • Lau, K.M.1    LaSpina, M.2    Long, J.3    Ho, S.M.4
  • 6
    • 20544459160 scopus 로고    scopus 로고
    • Receptor isoform and ligand-specific modulation of dihydrotestosterone-induced prostate specific antigen gene expression and prostate tumor cell growth by estrogens
    • discussion 509-510
    • Zhu YS, Cai LQ, Huang Y, Fish J, Wang L, Zhang ZK, Imperato-McGinley JL. Receptor isoform and ligand-specific modulation of dihydrotestosterone-induced prostate specific antigen gene expression and prostate tumor cell growth by estrogens. J Androl 2005;26:4500-4508; discussion 509-510.
    • (2005) J Androl , vol.26 , pp. 4500-4508
    • Zhu, Y.S.1    Cai, L.Q.2    Huang, Y.3    Fish, J.4    Wang, L.5    Zhang, Z.K.6    Imperato-McGinley, J.L.7
  • 8
    • 33646435242 scopus 로고    scopus 로고
    • Dihydrotestosterone, Testosterone, but not DHEA or Estradiol, differentially modulate IGF-I, IGFBP-2 and IGFBP-3 Gene and protein expression in primary cultures of human prostatic stromal cells
    • Le H, Arnold JT, McFann KK, Blackman MR. Dihydrotestosterone, Testosterone, but not DHEA or Estradiol, differentially modulate IGF-I, IGFBP-2 and IGFBP-3 Gene and protein expression in primary cultures of human prostatic stromal cells. Am J Physiol Endocrinol Metab 2005;290(5):E952-E960.
    • (2005) Am J Physiol Endocrinol Metab , vol.290 , Issue.5
    • Le, H.1    Arnold, J.T.2    McFann, K.K.3    Blackman, M.R.4
  • 9
    • 27844516613 scopus 로고    scopus 로고
    • Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
    • Liu X, Rubin JS, Kimmel AR. Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins. Curr Biol 2005;15(22):1989-1997.
    • (2005) Curr Biol , vol.15 , Issue.22 , pp. 1989-1997
    • Liu, X.1    Rubin, J.S.2    Kimmel, A.R.3
  • 10
    • 3843145374 scopus 로고    scopus 로고
    • Estrogens and anti-estrogens: Key mediators of prostate carcinogenesis and new therapeutic candidates
    • Ho SM. Estrogens and anti-estrogens: Key mediators of prostate carcinogenesis and new therapeutic candidates. J Cell Biochem 2004;91(3):491-503.
    • (2004) J Cell Biochem , vol.91 , Issue.3 , pp. 491-503
    • Ho, S.M.1
  • 11
    • 0031737726 scopus 로고    scopus 로고
    • Estrogen receptor-beta messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estrogenized rats
    • Prins GS, Marmer M, Woodham C, Chang W, Kuiper G, Gustafsson JA, Birch L. Estrogen receptor-beta messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estrogenized rats. Endocrinology 1998;139 (3):874-883.
    • (1998) Endocrinology , vol.139 , Issue.3 , pp. 874-883
    • Prins, G.S.1    Marmer, M.2    Woodham, C.3    Chang, W.4    Kuiper, G.5    Gustafsson, J.A.6    Birch, L.7
  • 14
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • Heinlein CA, Chang C. Androgen receptor in prostate cancer. Endocr Rev 2004;25(2):276-308.
    • (2004) Endocr Rev , vol.25 , Issue.2 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 15
    • 0036219874 scopus 로고    scopus 로고
    • Mechanisms involved in the progression of androgen-independent prostate cancers: It is not only the cancer cell's fault
    • Arnold JT, Isaacs JT. Mechanisms involved in the progression of androgen-independent prostate cancers: It is not only the cancer cell's fault. Endocr Relat Cancer 2002;9(1):61-73.
    • (2002) Endocr Relat Cancer , vol.9 , Issue.1 , pp. 61-73
    • Arnold, J.T.1    Isaacs, J.T.2
  • 16
    • 0024452707 scopus 로고
    • Steroid sulfate sulfatase in human benign prostatic hyperplasia: Characterization and quantification of the enzyme in epithelium and stroma
    • Klein H, Molwitz T, Bartsch W. Steroid sulfate sulfatase in human benign prostatic hyperplasia: Characterization and quantification of the enzyme in epithelium and stroma. J Steroid Biochem 1989;33(2):195-200.
    • (1989) J Steroid Biochem , vol.33 , Issue.2 , pp. 195-200
    • Klein, H.1    Molwitz, T.2    Bartsch, W.3
  • 17
    • 11144298641 scopus 로고    scopus 로고
    • Is there a receptor for dehydroepian-drosterone or dehydroepiandrosterone sulfate?
    • Widstrom RL, Dillon JS. Is there a receptor for dehydroepian-drosterone or dehydroepiandrosterone sulfate? Semin Reprod Med 2004;22(4):289-298.
    • (2004) Semin Reprod Med , vol.22 , Issue.4 , pp. 289-298
    • Widstrom, R.L.1    Dillon, J.S.2
  • 19
    • 0022386057 scopus 로고
    • Adrenal androgen blockade in relapsed prostate cancer
    • Geller J, Albert JD. Adrenal androgen blockade in relapsed prostate cancer. Eur J Cancer Clin Oncol 1985;21(10):1127-1131.
    • (1985) Eur J Cancer Clin Oncol , vol.21 , Issue.10 , pp. 1127-1131
    • Geller, J.1    Albert, J.D.2
  • 21
    • 26844575977 scopus 로고    scopus 로고
    • Does DHEA exert direct effects on androgen and estrogen receptors, and does it promote or prevent prostate cancer?
    • Arnold JT, Blackman MR. Does DHEA exert direct effects on androgen and estrogen receptors, and does it promote or prevent prostate cancer? Endocrinology 2005;146(11):4565-4567.
    • (2005) Endocrinology , vol.146 , Issue.11 , pp. 4565-4567
    • Arnold, J.T.1    Blackman, M.R.2
  • 22
    • 0032805744 scopus 로고    scopus 로고
    • Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis
    • De Marzo AM, Marchi VL, Epstein JI, Nelson WG. Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis. Am J Pathol 1999;155(6):1985-1992.
    • (1999) Am J Pathol , vol.155 , Issue.6 , pp. 1985-1992
    • De Marzo, A.M.1    Marchi, V.L.2    Epstein, J.I.3    Nelson, W.G.4
  • 23
    • 8644220601 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induced myofibroblasts regulate LNCaP cell death
    • Singh H, Dang TD, Ayala GE, Rowley DR. Transforming growth factor-beta1 induced myofibroblasts regulate LNCaP cell death. J Urol 2004;172 (6 Pt 1):2421-2425.
    • (2004) J Urol , vol.172 , Issue.6 PART 1 , pp. 2421-2425
    • Singh, H.1    Dang, T.D.2    Ayala, G.E.3    Rowley, D.R.4
  • 24
    • 0035931345 scopus 로고    scopus 로고
    • Crucial role of cytokines in sex steroid formation in normal and tumoral tissues
    • Simard J, Gingras S. Crucial role of cytokines in sex steroid formation in normal and tumoral tissues. Mol Cell Endocrinol 2001;171(1-2):25-40.
    • (2001) Mol Cell Endocrinol , vol.171 , Issue.1-2 , pp. 25-40
    • Simard, J.1    Gingras, S.2
  • 26
    • 0032743557 scopus 로고    scopus 로고
    • Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a
    • Zhao XY, Boyle B, Krishnan AV, Navone NM, Peehl DM, Feldman D. Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a. J Urol 1999;162(6):2192-2199.
    • (1999) J Urol , vol.162 , Issue.6 , pp. 2192-2199
    • Zhao, X.Y.1    Boyle, B.2    Krishnan, A.V.3    Navone, N.M.4    Peehl, D.M.5    Feldman, D.6
  • 27
    • 33746102558 scopus 로고    scopus 로고
    • Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells
    • Bhattacharyya RS, Krishnan AV, Swami S, Feldman D. Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells. Mol Cancer Ther 2006;5(6):1539-1549.
    • (2006) Mol Cancer Ther , vol.5 , Issue.6 , pp. 1539-1549
    • Bhattacharyya, R.S.1    Krishnan, A.V.2    Swami, S.3    Feldman, D.4
  • 30
    • 3042735780 scopus 로고    scopus 로고
    • Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7
    • Peekhaus NT, Chang T, Hayes EC, Wilkinson HA, Mitra SW, Schaeffer JM, Rohrer SP. Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7. J Mol Endocrinol 2004;32(3): 987-995.
    • (2004) J Mol Endocrinol , vol.32 , Issue.3 , pp. 987-995
    • Peekhaus, N.T.1    Chang, T.2    Hayes, E.C.3    Wilkinson, H.A.4    Mitra, S.W.5    Schaeffer, J.M.6    Rohrer, S.P.7
  • 31
    • 0033595102 scopus 로고    scopus 로고
    • Distinct effects on the conformation of estrogen receptor alpha and beta by both the antiestrogens ICI 164,384 and ICI 182,780 leading to opposite effects on receptor stability
    • Van Den Bemd GJ, Kuiper GG, Pols HA, Van Leeuwen JP. Distinct effects on the conformation of estrogen receptor alpha and beta by both the antiestrogens ICI 164,384 and ICI 182,780 leading to opposite effects on receptor stability. Biochem Biophys Res Commun 1999;261(1):1-5.
    • (1999) Biochem Biophys Res Commun , vol.261 , Issue.1 , pp. 1-5
    • Van Den Bemd, G.J.1    Kuiper, G.G.2    Pols, H.A.3    Van Leeuwen, J.P.4
  • 32
    • 0033755307 scopus 로고    scopus 로고
    • Antagonist/agonist balance of the nonsteroidal antiandrogen bicalutamide (Casodex) in a new prostate cancer model
    • Hobisch A, Hoffmann J, Lambrinidis L, Eder IE, Bartsch G, Klocker H, Culig Z. Antagonist/agonist balance of the nonsteroidal antiandrogen bicalutamide (Casodex) in a new prostate cancer model. Urol Int 2000;65(2):73-79.
    • (2000) Urol Int , vol.65 , Issue.2 , pp. 73-79
    • Hobisch, A.1    Hoffmann, J.2    Lambrinidis, L.3    Eder, I.E.4    Bartsch, G.5    Klocker, H.6    Culig, Z.7
  • 33
    • 0037226103 scopus 로고    scopus 로고
    • Novel mutations of androgen receptor: A possible mechanism of bicalutamide withdrawal syndrome
    • Hara T, Miyazaki J, Araki H, Yamaoka M, Kanzaki N, Kusaka M, Miyamoto M. Novel mutations of androgen receptor: A possible mechanism of bicalutamide withdrawal syndrome. Cancer Res 2003;63(1):149-153.
    • (2003) Cancer Res , vol.63 , Issue.1 , pp. 149-153
    • Hara, T.1    Miyazaki, J.2    Araki, H.3    Yamaoka, M.4    Kanzaki, N.5    Kusaka, M.6    Miyamoto, M.7
  • 34
    • 27544485276 scopus 로고    scopus 로고
    • Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient
    • Yoshida T, Kinoshita H, Segawa T, Nakamura E, Inoue T, Shimizu Y, Kamoto T, Ogawa O. Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient. Cancer Res 2005;65(21):9611-9616.
    • (2005) Cancer Res , vol.65 , Issue.21 , pp. 9611-9616
    • Yoshida, T.1    Kinoshita, H.2    Segawa, T.3    Nakamura, E.4    Inoue, T.5    Shimizu, Y.6    Kamoto, T.7    Ogawa, O.8
  • 35
    • 0037312834 scopus 로고    scopus 로고
    • Molecular basis for the subtype discrimination of the estrogen receptor-beta-selective ligand, diarylpropionitrile
    • Sun J, Baudry J, Katzenellenbogen JA, Katzenellenbogen BS. Molecular basis for the subtype discrimination of the estrogen receptor-beta-selective ligand, diarylpropionitrile. Mol Endocrinol 2003;17(2):247-258.
    • (2003) Mol Endocrinol , vol.17 , Issue.2 , pp. 247-258
    • Sun, J.1    Baudry, J.2    Katzenellenbogen, J.A.3    Katzenellenbogen, B.S.4
  • 36
    • 0037972896 scopus 로고    scopus 로고
    • Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ER beta in the uterus
    • Frasor J, Barnett DH, Danes JM, Hess R, Parlow AF, Katzenellenbogen BS. Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ER beta in the uterus. Endocrinology 2003;144(7):3159-3166.
    • (2003) Endocrinology , vol.144 , Issue.7 , pp. 3159-3166
    • Frasor, J.1    Barnett, D.H.2    Danes, J.M.3    Hess, R.4    Parlow, A.F.5    Katzenellenbogen, B.S.6
  • 37
    • 0030130570 scopus 로고    scopus 로고
    • 2-Phenylindoles with sulfur containing side chains. Estrogen receptor affinity, antiestrogenic potency, and antitumor activity
    • Biberger C, von Angerer E. 2-Phenylindoles with sulfur containing side chains. Estrogen receptor affinity, antiestrogenic potency, and antitumor activity. J Steroid Biochem Mol Biol 1996;58(1):31-43.
    • (1996) J Steroid Biochem Mol Biol , vol.58 , Issue.1 , pp. 31-43
    • Biberger, C.1    von Angerer, E.2
  • 39
    • 0034714893 scopus 로고    scopus 로고
    • Interactions between androgen and estrogen receptors and the effects on their transactivational properties
    • Panet-Raymond V, Gottlieb B, Beitel LK, Pinsky L, Trifiro MA. Interactions between androgen and estrogen receptors and the effects on their transactivational properties. Mol Cell Endocrinol 2000;167(1-2):139-150.
    • (2000) Mol Cell Endocrinol , vol.167 , Issue.1-2 , pp. 139-150
    • Panet-Raymond, V.1    Gottlieb, B.2    Beitel, L.K.3    Pinsky, L.4    Trifiro, M.A.5


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