Production of a polyclonal anti-myostatin antibody and the effects of in ovo administration of the antibody on posthatch broiler growth and muscle mass

Poultry Science

Volumn 86, Issue 6, 2007, Pages 1196-1205

  Kim, Y S ^a   Bobbili, N K ^a   Lee, Y K ^a   Jin, H J ^a,b   Dunn, M A ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b Gangneung Wonju National University   (South Korea)

Author keywords

Antibody; Broiler; Myostatin; Propeptide

Indexed keywords

AVES; ESCHERICHIA COLI; ORYCTOLAGUS CUNICULUS; SPONDIAS PURPUREA;

ANTIBODY; MYOSTATIN; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; CHICK EMBRYO; CHICKEN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; ORGAN SIZE; SKELETAL MUSCLE;

ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; CHICK EMBRYO; CHICKENS; GENE EXPRESSION REGULATION; MUSCLE, SKELETAL; ORGAN SIZE; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 34547673709     PISSN: 00325791     EISSN: 15253171     Source Type: Journal    
DOI: 10.1093/ps/86.6.1196     Document Type: Article

References (39)

1. Armand, A. S., G. B. Della, T. Launay, F. Charbonnier, C. L. Gallien, and C. Chanoine. 2003. Expression and neural control of follistatin versus myostatin genes during regeneration of mouse soleus. Dev. Dyn. 227:256-265.
2. Bogdanovich, S., T. O. Krag, E. R. Barton, L. D. Morris, L. A. Whittemore, R. S. Ahima, and T. S. Khurana. 2002. Functional improvement of dystrophic muscle by myostatin blockade. Nature 420:418-421.
3. Carlson, C. J., F. W. Booth, and S. E. Gordon. 1999. Skeletal muscle myostatin mRNA expression is fiber-type specific and increases during hindlimb unloading. Am. J. Physiol. 277:R601-R606.
4. Gonzalez-Cadavid, N. F., W. E. Taylor, K. Yarasheski, I. Sinha-Hikim, K. Ma, S. Ezzat, R. Shen, R. Lalani, S. Asa, M. Mamita, G. Nair, S. Arver, and S. Bhasin. 1998. Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting. Proc. Natl. Acad. Sci. USA 95:14938-14943.
5. Grobet, L., L. J. Martin, D. Poncelet, D. Pirottin, B. Brouwers, J. Riquet, A. Schoeberlein, S. Dunner, F. Menissier, J. Massabanda, R. Fries, R. Hanset, and M. Georges. 1997. A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat. Genet. 17:71-74.
6. Grobet, L., D. Pirottin, F. Farnir, D. Poncelet, L. J. Royo, B. Brouwers, E. Christians, D. Desmecht, F. Coignoul, R. Kahn, and M. Georges. 2003. Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene. Genesis 35:227-238.
7. Kambadur, R., M. Sharma, T. P. Smith, and J. J. Bass. 1997. Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle. Genome Res. 7:910-916.
8. Kim, Y. S., N. K. Bobbili, K. S. Paek, and H. J. Jin. 2006. Production of a monoclonal anti-myostatin antibody and the effects of in ovo administration of the antibody on posthatch broiler growth and muscle mass. Poult. Sci. 85:1062-1071.
9. Kirk, S., J. Oldham, R. Kambadur, M. Sharma, P. Dobbie, and J. Bass. 2000. Myostatin regulation during skeletal muscle regeneration. J. Cell. Physiol. 184:356-363.
10. Kocamis, H., D. C. Kirkpatrick-Keller, H. Klandorf, and J. Killefer. 1998. In ovo administration of recombinant human insulin-like growth factor-I alters postnatal growth and development of the broiler chicken. Poult. Sci. 77:1913-1919.
11. Kocamis, H., Y. N. Yeni, D. C. Kirkpatrick-Keller, and J. Killefer. 1999. Postnatal growth of broilers in response to in ovo administration of chicken growth hormone. Poult. Sci. 78:1219-1226.
12. Laemmli, U. K. 1970. Cleavage of structural proteinsduring the assembly of the head of bacteriophage T4. Nature 227:680-685.
13. Lalani, R., S. Bhasin, F. Byhower, R. Tarnuzzer, M. Grant, R. Shen, S. Asa, S. Ezzat, and N. F. Gonzalez-Cadavid. 2000. Myostatin and insulin-like growth factor-I and -II expression in the muscle of rats exposed to the microgravity environment of the NeuroLab space shuttle flight. J. Endocrinol. 167:417-428.
14. Langley, B., M. Thomas, A. Bishop, M. Sharma, S. Gilmour, and R. Kambadur. 2002. Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J. Biol. Chem. 277:49831-49840.
15. Lee, Y. K. 2003. Production and characterization of polyclonal antibodies against chicken myostain. MS Thesis Univ. Hawaii, Manoa.
16. Lee, S. J., and A. C. McPherron. 2001. Regulation of myostatin activity and muscle growth. Proc. Natl. Acad. Sci. USA 98:9306-9311.
17. McCroskery, S., M. Thomas, L. Maxwell, M. Sharma, and R. Kambadur. 2003. Myostatin negatively regulates satellite cell activation and self-renewal. J. Cell Biol. 162:1135-1147.
18. McFarlane, C., E. Plummer, M. Thomas, A. Hennebry, M. Ashby, N. Ling, H. Smith, M. Sharma, and R. Kambadur. 2006. Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism. J. Cell. Physiol. 209:501-514.
19. McFarland, D. C., S. G. Velleman, J. E. Pesall, and C. Liu. 2006. Effect of myostatin on turkey myogenic satellite cells and embryonic myoblasts. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 144:501-508.
20. McPherron, A. C., A. M. Lawler, and S. J. Lee. 1997. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387:83-90.
21. Mendler, L., E. Zador, H. M. Ver, L. Dux, and F. Wuytack. 2000. Myostatin levels in regenerating rat muscles and in myogenic cell cultures. J. Muscle Res. Cell Motil. 21:551-563.
22. Reardon, K. A., J. Davis, R. M. Kapsa, P. Choong, and E. Byrne. 2001. Myostatin, insulin-like growth factor-1, and leukemia inhibitory factor mRNAs are upregulated in chronic human disuse muscle atrophy. Muscle Nerve 24:893-899.
23. Reisz-Porszasz, S., S. Bhasin, J. N. Artaza, R. Shen, I. Sinha-Hikim, A. Hogue, T. J. Fielder, and N. F. Gonzalez-Cadavid. 2003. Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin. Am. J. Physiol. Endocrinol. Metab. 285:E876-E888.
24. Rios, R., I. Carneiro, V. M. Arce, and J. Devesa. 2002. Myostatin is an inhibitor of myogenic differentiation. Am. J. Physiol. Cell Physiol. 282:C993-C999.
25. Ryoo, H., M. Lee, and Y. Kim. 2006. Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells. Gene 365:51-57.
26. Sato, F., M. Kurokawa, N. Yamauchi, and M. A. Hattori. 2006. Gene silencing of myostatin in differentiation of chicken embryonic myoblasts by small interfering RNA 41. Am. J. Physiol. Cell Physiol. 291:C538-C545.
27. Schuelke, M., K. R. Wagner, L. E. Stolz, C. Hubner, T. Riebel, W. Komen, T. Braun, J. F. Tobin, and S. J. Lee. 2004. Myostatin mutation associated with gross muscle hypertrophy in a child. New Engl. J. Med. 350:2682-2688.
28. Sharma, M., R. Kambadur, K. G. Matthews, W. G. Somers, G. P. Devlin, J. V. Conaglen, P. J. Fowke, and J. J. Bass. 1999. Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct. J. Cell. Physiol. 180:1-9.
29. Taylor, W. E., S. Bhasin, J. Artaza, F. Byhower, M. Azam, D. H. Willard, Jr., F. C. Kull, Jr., and N. Gonzalez-Cadavid. 2001. Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cells. Am. J. Physiol. Endocrinol. Metab. 280:E221-E228.
30. Thies, R. S., T. Chen, M. V. Davies, K. N. Tomkinson, A. A. Pearson, Q. A. Shakey, and N. M. Wolfman. 2001. GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding. Growth Factors 18:251-259.
31. Thomas, M., B. Langley, C. Berry, M. Sharma, S. Kirk, J. Bass, and R. Kambadur. 2000. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J. Biol. Chem. 275:40235-40243.
32. van den Berg, W. B., P. M. van der Kraan, A. Scharstuhl, and H. M. van Beuningen. 2001. Growth factors and cartilage repair. Clin. Orthop. Relat. Res. 319:S244-S250.
33. Wehling, M., B. Cai, and J. G. Tidball. 2000. Modulation of myostatin expression during modified muscle use. FASEB J. 14:103-110.
34. Welle, S., K. Bhatt, B. Shah, and C. Thornton. 2002. Insulin-like growth factor-1 and myostatin mRNA expression in muscle: Comparison between 62-77 and 21-31 yr old men. Exp. Gerontol. 37:833-839.
35. Whittemore, L. A., K. Song, X. Li, J. Aghajanian, M. Davies, S. Girgenrath, J. J. Hill, M. Jalenak, P. Kelley, A. Knight, R. Maylor, D. O'Hara, A. Pearson, A. Quazi, S. Ryerson, X. Y. Tan, K. N. Tomkinson, G. M. Veldman, A. Widom, J. F. Wright, S. Wudyka, L. Zhao, and N. M. Wolfman. 2003. Inhibition of myostatin in adult mice increases skeletal muscle mass and strength. Biochem. Biophys. Res. Commun. 300:965-971.
36. Wolfman, N. M., A. C. McPherron, W. N. Pappano, M. V. Davies, K. Song, K. N. Tomkinson, J. F. Wright, L. Zhao, S. M. Sebald, D. S. Greenspan, and S. J. Lee. 2003. Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. Proc. Natl. Acad. Sci. USA 100:15842-15846.
37. Yamaguchi, A., T. Fujikawa, M. Tateoka, H. Soya, K. Sakuma, T. Sugiura, I. Morita, Y. Ikeda, and T. Hirai. 2006. The expression of IGF-I and myostatin mRNAs in skeletal muscle of hypophysectomized and underfed rats during postnatal growth. Acta Physiol. (Oxf.) 186:291-300.
38. Yang, J., T. Ratovitski, J. P. Brady, M. B. Solomon, K. D. Wells, and R. J. Wall. 2001. Expression of myostatin pro domain results in muscular transgenic mice. Mol. Reprod. Dev. 60:351-361.
39. Zimmers, T. A., M. V. Davies, L. G. Koniaris, P. Haynes, A. F. Esquela, K. N. Tomkinson, A. C. McPherron, N. M. Wolfman, and S. J. Lee. 2002. Induction of cachexia in mice by systemically administered myostatin. Science 296:1486-1488.