A convenient solution and solid-phase synthesis of Δ5-2-oxopiperazines via N-acyliminium ions cyclization

Tetrahedron Letters

Volumn 43, Issue 36, 2002, Pages 6293-6295

  Cheng, Jie Fei ^a   Chen, Mi ^a   Arrhenius, Thomas ^a   Nadzan, Alex ^a  

^a LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; AMIDE; IMINE; ION; N ACYLIMINIUM; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CYCLIZATION; LIQUID; POLYMERIZATION; SOLID; SYNTHESIS;

EID: 0037009683     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01403-X     Document Type: Article

References (18)

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13. . See for example: Strocker A.M., Keating T.A., Tempest P.A., Armstrong R.W. Tetrahedron Lett. 37:1996;1149.
14. Immobilization of isocyanide strategy: (a) Arshady, R.; Ugi, I. Z. Naturforsch. 1981, 36b, 1202. The isocyanomethyl resin is recently made available by Bachem Biosciences Inc. (b) Short, K.; Ching, B.; Mjalli, A. M. M. Tetrahedron 1997, 53, 6653.
15. Immobilization of isocyanide strategy: (a) Arshady, R.; Ugi, I. Z. Naturforsch. 1981, 36b, 1202. The isocyanomethyl resin is recently made available by Bachem Biosciences Inc. (b) Short, K.; Ching, B.; Mjalli, A. M. M. Tetrahedron 1997, 53, 6653.
16. Convertible isocyanide strategy: (a) Strocker, A. M.; Keating, T. A.; Tempest, P. A.; Armstrong, R. W. Tetrahedron Lett. 1996, 37, 1149; (b) Tempest, P. A.; Brown, S. D.; Armstrong, R. W. Angew. Chem., Int. Ed. Engl. 1996, 35, 640.
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18. 3CN) δ 19.5, 20.2, 30.3, 34.3, 48.3, 53.3, 62.1, 110.4, 116.3 (2C), 117.1, 118.6 (2C), 129.4, 130.5 (2C), 130.7, 131.3 (2C), 133.0, 140.1, 156.8, 165.2 (CON), 167.3 (CON), 169.0 (COO).