Malnutrition enhances cardiovascular responses to chemoreflex activation in awake rats

Life Sciences

Volumn 81, Issue 7, 2007, Pages 609-614

  Penitente, Arlete Rita ^a   Fernandes, Luciano Gonçalves ^a   Cardoso, Leonardo Máximo ^a   Silva, Marcelo Eustáquio ^a   Pedrosa, Maria Lúcia ^a   Silva, Antônio Leite ^a   Haibara, Andréa Siqueira ^b   Moraes, Márcio Flávio Dutra ^b   Chianca, Deoclécio Alves ^a  

^a FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Albumin; Arterial pressure; Chemoreflex; Low protein diet; Sympathetic activity

Indexed keywords

ALBUMIN; GLUCOSE; PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; BRADYCARDIA; CARDIOVASCULAR REFLEX; CARDIOVASCULAR RESPONSE; CAROTID ARTERY LIGATION; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; HEART RATE; MALE; MALNUTRITION; MEAN ARTERIAL PRESSURE; NEUROTRANSMISSION; NONHUMAN; PRESSOR RESPONSE; PROTEIN RESTRICTION; RAT; STATISTICAL ANALYSIS; SYMPATHETIC TONE; WAKEFULNESS; WEANING;

ANIMALS; AUTONOMIC NERVOUS SYSTEM; BLOOD GLUCOSE; BLOOD PRESSURE; BLOOD PROTEINS; CARDIOVASCULAR PHYSIOLOGY; CAROTID ARTERIES; CAROTID BODY; DIET; HEART RATE; MALE; MALNUTRITION; POTASSIUM CYANIDE; RATS; RATS, INBRED F344; REFLEX; SERUM ALBUMIN;

ANIMALIA; RATTUS;

EID: 34547670206     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.07.006     Document Type: Article

References (37)

1. Agarwal K.N., Prasad C., and Taneja V. Protein deprivation and the brain: effect on enzymes and free amino acids related to glutamate metabolism in rats. Annals of Nutrition & Metabolism 25 (1981) 228-233
2. Barker D.J., Bull A.R., Osmond C., and Simmonds S.J. Fetal and placental size and risk of hypertension in adult life. British Medical Journal 301 (1990) 259-262
3. Barker D.J., Gluckman P.D., Godfrey K.M., Harding J.E., Owens J.A., and Robinson J.S. Fetal nutrition and cardiovascular disease in adult life. Lancet 341 (1993) 938-941
4. Barros R.C., Bonagamba L.G., Okamoto-Canesin R., de Oliveira M., Branco L.G., and Machado B.H. Cardiovascular responses to chemoreflex activation with potassium cyanide or hypoxic hypoxia in awake rats. Autonomic Neuroscience 97 (2002) 110-115
5. Benabe J.E., and Martinez-Maldonado M. Dietary modification of the renin angiotensin system. Seminars in Nephrology 13 (1993) 567-572
6. Benabe J.E., and Martinez-Maldonado M. The impact of malnutrition on kidney function. Mineral and Electrolyte Metabolism 24 (1998) 20-26
7. Benabe J.E., Fernandez-Repollet E., Tapia E., Luo C., and Martinez-Maldonado M. Angiotensin II and catecholamines interaction in short-term low protein feeding. Kidney International 44 (1993) 285-293
8. Benabe J.E., Wang S., Wilcox J.N., and Martinez-Maldonado M. Modulation of ANG II receptor and its mRNA in normal rat by low-protein feeding. American Journal of Physiology 265 (1993) F660-F669
9. Dick T.E., Hsieh Y.H., Wang N., and Prabhakar N. Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat. Experimental Physiology 92 (2007) 87-97
10. Efron D.T., and Barbul A. Arginine and nutrition in renal disease. Journal of Renal Nutrition 9 (1999) 142-144
11. Fletcher E.C. Hypertension in patients with sleep apnoea, a combined effect?. Thorax 55 (2000) 726-728
12. Fletcher E.C. Invited review: physiological consequences of intermittent hypoxia: systemic blood pressure. Journal of Applied Physiology 90 (2001) 1600-1605
13. Fletcher E.C., Orolinova N., and Bader M. Blood pressure response to chronic episodic hypoxia: the renin-angiotensin system. Journal of Applied Physiology 92 (2002) 627-633
14. Franchini K.G., and Krieger E.M. Carotid chemoreceptors influence arterial pressure in intact and aortic-denervated rats. American Journal of Physiology 262 (1992) R677-R683
15. Franchini K.G., and Krieger E.M. Cardiovascular responses of conscious rats to carotid body chemoreceptor stimulation by intravenous KCN. Journal of the Autonomic Nervous System 42 (1993) 63-69
16. Gonzalez C., Lopez-Lopez J.R., Obeso A., Perez-Garcia M.T., and Rocher A. Cellular mechanisms of oxygen chemoreception in the carotid body. Respiration Physiology 102 (1995) 137-147
17. Haibara A.S., Colombari E., Chianca Jr. D.A., Bonagamba L.G., and Machado B.H. NMDA receptors in NTS are involved in bradycardic but not in pressor response of chemoreflex. American Journal of Physiology 269 (1995) H1421-H1427
18. Haibara A.S., Bonagamba L.G., and Machado B.H. Sympathoexcitatory neurotransmission of the chemoreflex in the NTS of awake rats. American Journal of Physiology 276 (1999) R69-R80
19. Hawkins P., Steyn C., McGarrigle H.H., Saito T., Ozaki T., Stratford L.L., Noakes D.E., and Hanson M.A. Effect of maternal nutrient restriction in early gestation on responses of the hypothalamic-pituitary-adrenal axis to acute isocapnic hypoxaemia in late gestation fetal sheep. Experimental Physiology 85 (2000) 85-96
20. Irigoyen M.C., Paulini J., Flores L.J., Flues K., Bertagnolli M., Moreira E.D., Consolim-Colombo F., Bello-Klein A., and De Angelis K. Exercise training improves baroreflex sensitivity associated with oxidative stress reduction in ovariectomized rats. Hypertension 46 (2005) 998-1003
21. Langley-Evans S.C., Phillips G.J., Benediktsson R., Gardner D.S., Edwards C.R., Jackson A.A., and Seckl J.R. Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat. Placenta 17 (1996) 169-172
22. Langley-Evans S.C., Langley-Evans A.J., and Marchand M.C. Nutritional programming of blood pressure and renal morphology. Archives of Physiology and Biochemistry 111 (2003) 8-16
23. Mancia G. Bjorn Folkow Award Lecture. The sympathetic nervous system in hypertension. Journal of Hypertension 15 (1997) 1553-1565
24. Marshall J.M. Peripheral chemoreceptors and cardiovascular regulation. Physiological Reviews 74 (1994) 543-594
25. Oliveira E.L., Cardoso L.M., Pedrosa M.L., Silva M.E., Dun N.J., Colombari E., Moraes M.F., and Chianca Jr. D.A. A low protein diet causes an increase in the basal levels and variability of mean arterial pressure and heart rate in Fisher rats. Nutritional Neuroscience 7 (2004) 201-205
26. Pimentel F.F., Bonagamba L.G., and Machado B.H. Pressor response to chemoreflex activation before and after microinjection of glycine into the NTS of awake rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 284 (2003) R1000-R1009
27. Plagemann A., Harder T., Rake A., Melchior K., Rohde W., and Dorner G. Hypothalamic nuclei are malformed in weanling offspring of low protein malnourished rat dams. Journal of Nutrition 130 (2000) 2582-2589
28. Prabhakar N.R., Dick T.E., Nanduri J., and Kumar G.K. Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia. Experimental Physiology 92 (2007) 39-44
29. Sapru H.N., and Krieger A.J. Carotid and aortic chemoreceptor function in the rat. Journal of Applied Physiology 42 (1977) 344-348
30. Sawaya A.L., Martins P., Hoffman D., and Roberts S.B. The link between childhood undernutrition and risk of chronic diseases in adulthood: a case study of Brazil. Nutrition Reviews 61 (2003) 168-175
31. Sinski M., Lewandowski J., Abramczyk P., Narkiewicz K., and Gaciong Z. Why study sympathetic nervous system?. Journal of Physiology and Pharmacology 57 Suppl 11 (2006) 79-92
32. Tahawi Z., Orolinova N., Joshua I.G., Bader M., and Fletcher E.C. Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats. Journal of Applied Physiology 90 (2001) 2007-2013
33. Tonkiss J., Trzcinska M., Galler J.R., Ruiz-Opazo N., and Herrera V.L. Prenatal malnutrition-induced changes in blood pressure: dissociation of stress and nonstress responses using radiotelemetry. Hypertension 32 (1998) 108-114
34. Tropia F.C., Cardoso L.M., Pedrosa M.L., Silva M.E., Haibara A.S., Moraes M.F., and Chianca Jr. D.A. Effects of low-protein diet on the baroreflex and Bezold-Jarisch reflex in conscious rats. Nutritional Neuroscience 4 (2001) 99-107
35. Vasquez E.C., Meyrelles S.S., Mauad H., and Cabral A.M. Neural reflex regulation of arterial pressure in pathophysiological conditions: interplay among the baroreflex, the cardiopulmonary reflexes and the chemoreflex. Brazilian Journal of Medical and Biological Research 30 (1997) 521-532
36. Woods S.E., and Raju U. Maternal smoking and the risk of congenital birth defects: a cohort study. Journal of the American Board of Family Practice 14 (2001) 330-334
37. Young J.B., Kaufman L.N., Saville M.E., and Landsberg L. Increased sympathetic nervous system activity in rats fed a low-protein diet. American Journal of Physiology 248 (1985) R627-R637