Study on mechanism of Abnormal Savda Munziq flavonoids in induction of apoptosis of Hep2 cells

Zhongguo Zhongyao Zazhi

Volumn 32, Issue 11, 2007, Pages 1068-1071

  Yusup, Abdiryim ^a,b   Upur, Halmurat ^a   Tursun, Xirali ^b   Berke, Bénédicte ^c   Baudrimont, Isabelle ^c   Moore, Nicholas ^c  

^a XINJIANG MEDICAL UNIVERSITY   (China)

^b Xinjiang Institute of Traditional Uighur Medicine   (China)

^c UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Abnormal Savda Munziq; Apoptosis; Flavonoid; HepG2

Indexed keywords

ANTINEOPLASTIC AGENT; FLAVONOID; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL PROLIFERATION; CHEMISTRY; DRUG COMBINATION; DRUG EFFECT; FLOW CYTOMETRY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; LIVER CELL CARCINOMA; LIVER TUMOR; MEDICINAL PLANT; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG COMBINATIONS; FLAVONOIDS; FLOW CYTOMETRY; HUMANS; LIVER NEOPLASMS; PLANTS, MEDICINAL; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS P21(RAS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34547634400     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Ren W, Qiao Z, Wang H, et al. Flavonoids: promising anticancer agents[J]. Med Res Rev, 2003,23(4):519.
2. Yao L H, Jiang Y M, Shi J, et al. Flavonoids in food and their health benefits[J]. Plant Foods Hum Nutr, 2004,59(3):113.
3. Chinese source
4. Abdiryim Y, Halmurat U, Baudrimont I, et al. Cytotoricity of abnormal Savda Munziq aqueous extract in human hepatoma (HepG2) Cells[J]. Fundam Clin Pharmacol, 2005,19(4):465.
5. Abid Essefi S, Baudrimont I, Hassen W, et al. DNA fragmentation, apoptosis and cell cycle arrest induced by zearalenone in cultured DOK, Vero and Caco-2 cells; prevention by Vitamin E[J]. Toxicology, 2003,192(2-3):237.
6. Huang S T, Yang R C, Chen M Y, et al. Phyllanthus urinaria induces the fas receptor/ligand expression and ceramide-mediated apoptosis in HL-60 cells[J]. Life Sci, 2004,75(3):339.
7. Hendrich A B. Flavonoid-membrane interactions: possible consequences for biological effects of some polyphenolic compounds[J]. Acta Pharmacol Sin, 2006,27(1):27.
8. Kanadaswami C, Lee L T, Lee P P, et al. The antitumor activities of flavonoids[J]. In Vivo, 2005,19(5):895.
9. Chinese source
10. Halmurat U, Abdiryim Y, Anwar U, et al. Uighur traditional medicine syndrome of Abnormal Savda in men is associated with oxidative stress, which can be improved by Munziq and Mushil of Abnormal Savda[J]. Therapie, 2004,59(4):483.
11. Chinese source
12. Abdiryim Y, Halmurat U, Anwar U, et al. Protective effects of Munziq and Mushil of abnormal Savda to mitochondrial oxidative damage[J]. Fundam Clin Pharmacol, 2004,18(4):471.