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Journal of Molecular Modeling

Volumn 13, Issue 9, 2007, Pages 993-1000

3D-QSAR studies on fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors by CoMFA and CoMSIA

(4) Zeng, Juan a Liu, Guixia a Tang, Yun a Jiang, Hualiang a,b

a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (China)

b SHANGHAI INSTITUTE OF MATERIA MEDICA (China)

Author keywords

3D QSAR; CoMFA; CoMSIA; Diabetes mellitus; Dipeptidyl peptidase IV (DP IV)

Indexed keywords

4 AMINOCYCLOHEXYLGLYCINE DERIVATIVE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLYCINE DERIVATIVE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; COMPUTER PROGRAM; CONCENTRATION RESPONSE; CONSTANTS AND COEFFICIENTS; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHOBICITY; IN VITRO STUDY; LIGAND BINDING; MATHEMATICAL COMPUTING; MOLECULAR INTERACTION; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING; VALIDATION STUDY;

AMIDES; ANTIGENS, CD26; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; PYRROLIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34547626099 PISSN: 16102940 EISSN: 09485023 Source Type: Journal
DOI: 10.1007/s00894-007-0221-8 Document Type: Article

Times cited : (21)

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