Fluoroquinolone resistance in atypical pneumococci and oral streptococci: Evidence of horizontal gene transfer of fluoroquinolone resistance determinants from Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 8, 2007, Pages 2690-2700

  Ip, Margaret ^a   Chau, Shirley S L ^a   Chi, Fang ^a   Tang, Julian ^a   Chan, Paul K ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISERUM; AUTOLYSIN; CIPROFLOXACIN; DNA TOPOISOMERASE; ETHYLHYDROCUPREINE; GYRASE INHIBITOR; PNEUMOLYSIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RNA 16S;

ALPHA HEMOLYTIC STREPTOCOCCUS; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIGEN ANTIBODY REACTION; ARTICLE; ATYPICAL MYCOBACTERIUM; BACTEREMIA; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BILE; BILE SOLUBILITY; GENE CLUSTER; GENE MUTATION; GENE SEQUENCE; GENE TRANSFER; GENETIC ANALYSIS; GENOTYPE; GYRA GENE; GYRB GENE; HUMAN; MINIMUM INHIBITORY CONCENTRATION; MULTILOCUS SEQUENCE TYPING; NONHUMAN; OPTOCHIN SUSCEPTIBILITY; PARC GENE; PARE GENE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RNA SEQUENCE; SEROTYPE; SOLUBILITY; STREPTOCOCCUS; STREPTOCOCCUS MITIS; STREPTOCOCCUS ORALIS; STREPTOCOCCUS PNEUMONIAE;

AMINO ACID SUBSTITUTION; ANTI-INFECTIVE AGENTS; BACTERIAL PROTEINS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; GENE TRANSFER, HORIZONTAL; GENOTYPE; HUMANS; MICROBIAL SENSITIVITY TESTS; PHENOTYPE; PHYLOGENY; STREPTOCOCCUS; STREPTOCOCCUS MITIS; STREPTOCOCCUS ORALIS; STREPTOCOCCUS PNEUMONIAE;

EID: 34547615768     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00258-07     Document Type: Article

References (39)

1. Adam, H. J., K. N. Schurek, K. A. Nichol, C. J. Hoban, T. J. Baudry, N. M. Laing, D. J. Hoban, and G. G. Zhanel. 2007. Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae in Canada, 1997 to 2005. Antimicrob. Agents Chemother. 51:198-207.
2. Arbique, J. C., C. Poyart, P. Trieu-Cuot, G. Quesne, G. Carvalho Mda, A. G. Steigerwalt, R. E. Morey, D. Jackson, R. J. Davidson, and R. R. Facklam. 2004. Accuracy of phenotypic and genotypic testing for identification of Streptococcus pneumoniae and description of Streptococcus pseudopneumoniae sp. nov. J. Clin. Microbiol. 42:4686-4696.
3. Balsalobre, L. M. J. Ferrandiz, J. Linares, F. Tubau, and A. G. de la Campa. 2003. Viridans group streptococci are donors in horizontal transfer of topoisomerase IV genes to Streptococcus pneumoniae. Antimicrob. Agents Chemother. 47:2072-2081.
4. Bast, D. J., D. E. Low, C. L. Duncan, L. Kilburn, L. A. Mandell, R. J. Davidson, and J. C. de Azavedo. 2000. Fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae: contributions of type II topoisomerase mutations and efflux to levels of resistance. Antimicrob. Agents Chemother. 44:3049-3054.
5. Borek, A. P., D. C. Dressel, J. Hussong, and L. R. Peterson. 1997. Evolving clinical problems with Streptococcus pneumoniae: increasing resistance to antimicrobial agents, and failure of traditional optochin identification in Chicago, Illinois, between 1993 and 1996. Diagn. Microbiol. Infect. Dis. 29:209-214.
6. Brenwald, N. P., M. J. Gill, and R. Wise. 1998. Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemother. 42:2032-2035.
7. Chi, F., O. Nolte, C. Bergmann, M. Ip, and R. Hakenbeck. 2007. Crossing the barrier: Evolution and spread of a major class of mosaic pbp2x in Streptococcus pneumoniae, S. mitis and S. oralis. Int. J. Med. Microbiol. doi:10.1016/ j-ijmm.2007.02.009.
8. Clinical Laboratory Standards Institute. 2004. Performance standards for antimicrobial susceptibility testing, M100-S14. Clinical Laboratory Standards Institute, Wayne, PA.
9. de la Campa, A. G., L. Balsalobre, C. Ardanuy, A. Fenoll, E. Perez-Trallero, J. Linares, and Spanish Pneumococcal Infection Study Network G03/103. 2004. Fluoroquinolone resistance in penicillin-resistant Streptococcus pneumoniae clones, Spain. Emerg. Infect. Dis. 10:1751-1759.
10. Denys, G. A., and R. B. Carey. 1992. Identification of Streptococcus pneumoniae with a DNA probe. J. Clin. Microbiol. 30:2725-2727.
11. Gonzalez, I., M. Georgiou, F. Alcaide, D. Balas, J. Linares, and A. G. de la Campa. 1998. Fluoroquinolone resistance mutations in the parC, parE, and gyrA genes of clinical isolates of viridans group streptococci. Antimicrob. Agents Chemother. 42:2792-2798.
12. Guerin, F., E. Varon, A. B. Hoi, L. Gutmann, and I. Podglajen. 2000. Fluoroquinolone resistance associated with target mutations and active efflux in oropharyngeal colonizing isolates of viridans group streptococci. Antimicrob. Agents Chemother. 44:2197-2200.
13. Hanage, W. P., T. Kaijalainen, E. Herva, A. Saukkoriipi, R. Syrjanen, and B. J. Spratt. 2005. Using multilocus sequence data to define the pneumococcus. J. Bacteriol. 187:6223-6230.
14. Hanage, W. P., B. J. Spratt, K. M. E. Turner, and C. Fraser. 2006. Modelling bacterial speciation. Philos. Trans. R. Soc. Lond. B 261:2039-2044.
15. Ho, P. L., R. W. Yung, D. N. Tsang, T. L. Que, M. Ho, W. H. Seto, T. K. Ng, W. C. Yam, and W. W. Ng. 2001. Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: results of a Hong Kong multicentre study in 2000. J. Antimicrob. Chemother. 48:659-665.
16. Ho, P. L., T. L. Que, S. S. Chiu, R. W. H. Yung, T. K. Ng, D. N. C. Tsang, W. H. Seto, and Y. L. Lau. 2004. Fluoroquinolone and other antimicrobial resistance in invasive pneumococci, Hong Kong, 1995-2001. Emerg. Infect. Dis. 7:1250-1257.
17. Ip, M., S. S. Chau, F. Chi, A. Qi, and R. W. Lai. 2006. Rapid screening of fluoroquinolone resistance determinants in Streptococcus pneumoniae by PCR-restriction fragment length polymorphism and single-strand conformational polymorphism. J. Clin. Microbiol. 44:970-975.
18. Ip, M., F. Chi, S. S. L. Chau, M. Hui, J. Tang, and P. K. S. Chan. 2006. Use of the housekeeping genes, gdh (zwf) and gki, in multilocus sequence typing (MLST) to differentiate S. pneumoniae from S. mitis and S. oralis. Diagn. Microbiol. Infect. Dis. 56:321-324.
19. Janoir, C., I. Podglajen, M. D. Kitzis, C. Poyart, and L. Gutmann. 1999. In vitro exchange of fluoroquinolone resistance determinants between Streptococcus pneumoniae and viridans streptococci and genomic organization of the parE-parC region in S. mitis. J. Infect. Dis. 180:555-558.
20. Kawamura, Y., X. Hou, F. Sultana, H. Miura, and T. Ezaki. 1995. Determination of 16S rRNA sequences of Streptococcus mitis and Streptococcus gordonii and phylogenetic relationships among members of the genus Streptococcus. Int. J. Syst. Bacteriol. 45:406-408.
21. Kellogg, J. A., D. A. Bankert, C. J. Elder, J. L. Gibbs, and M. C. Smith. 2001. Identification of Streptococcus pneumoniae revisited. J. Clin. Microbiol. 39: 3373-3375.
22. Ko, K. S., W. S. Oh, K. R. Peck, J. H. Lee, N. Y. Lee, and J. H. Song. 2005. Phenotypic and genotypic discrepancy of Streptococcus pneumoniae strains isolated from Asian countries. FEMS Immunol. Med. Microbiol. 45:63-70.
23. Kumar, S., K. Tamura, and M. Nei. 2004. MEGA3: integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief. Bioinform. 5:150-163.
24. Mandell, L. A., J. G. Bartlett, S. F. Dowell, T. M. File, Jr., D. M. Musher, and C. Whitney. 2003. Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults. Clin. Infect. Dis. 37:1405-1433.
25. Mandell, L. A., T. J. Marrie, R. F. Grossman, A. W. Chow, R. H. Hyland, Canadian Infectious Disease Society, and Canadian Thoracic Society. 2000. Summary of Canadian guidelines for the initial management of community-acquired pneumonia: an evidence-based update by the Canadian Infectious Disease Society and the Canadian Thoracic Society. Can. Respir. J. 7:371-382.
26. Martin-Galiano, A. J., L. Balsalobre, A. Fenoll, and A. G. de la Campa. 2003. Genetic characterization of optochin-susceptible viridans group streptococci. Antimicrob. Agents Chemother. 47:3187-3194.
27. Muñoz, R., and A. G. De La Campa. 1996. ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyrase A subunit in forming resistance phenotype. Antimicrob Agents Chemother. 40:2252-2257.
28. Neeleman, C., C. H. W. Klaassen, D. M. Klomberg, H. A. de Valk, and J. W. Mouton. 2004. Pneumolysin is a key factor in misidentification of macrolide-resistant Streptococcus pneumoniae and is a putative virulence factor of S. mitis and other streptococci. J. Clin. Microbiol. 42:4355-4357.
29. Picard, F. J., D. Ke, D. K. Boudreau, M. Boissinot, A. Huletsky, D. Richard, M. Ouellette, P. H. Roy, and M. G. Bergeron. 2004. Use of tuf sequences for genus-specific PCR detection and phylogenetic analysis of 28 streptococcal species. J. Clin. Microbiol. 42:3686-3695.
30. Pikis, A., J. M. Campos, W. J. Rodriguez, and J. M. Keith. 2001. Optochin resistance in Streptococcus pneumoniae: mechanism, significance, and clinical implications. J. Infect. Dis. 184:582-590.
31. Pletz, M. W. R., L. McGee, B. Beall, C. G. Whitney, and K. P. Klugman. 2005. Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States. Antimicrob Agents Chemother. 49: 779-780.
32. Poyart, C., G. Quesne, S. Coulon, P. Berche, and P. Trieu-Cuot. 1998. Identification of streptococci to species level by sequencing the gene encoding the manganese-dependent superoxide dismutase. J. Clin. Microbiol. 36: 41-47.
33. Richter, S. S., K. P. Heilmann, S. E. Beekmann, N. J. Miller, C. L. Rice, and G. V. Doern. 2005. The molecular epidemiology of Streptococcus pneumoniae with quinolone resistance mutations. Clin. Infect. Dis. 40:225-235.
34. Rudolph, K. M., A. J. Parkinson, C. M. Black, and L. W. Mayer. 1993. Evaluation of polymerase chain reaction for diagnosis of pneumococcal pneumonia. J. Clin. Microbiol. 31:2661-2666.
35. Song, J. H., S. I. Jung, S. K. Kwan, Y. K. Na, J. S. Son, H. H. Chang, H. K. Ki, W. S. Oh, J. Y. Suh, K. R. Peck, N. Y. Lee, Y. H. Yang, Q. Lu, A. Chongthaleong, C. H. Chiu, M. K. Lalitha, J. Perera, T. T. Yee, G. Kumarasinghe, F. Jamal, A. Kamarulzaman, N. Parasakthi, P. H. Van, C. Carlos, T. So, T. K. Ng, and A. Shibl. 2004. High prevalence of antimicrobial resistance among clinical Streptococcus pneumoniae isolates in Asia (an ANSORP study). Antimicrob. Agents Chemother. 48:2101-2107.
36. Stanhope, M. J., S. L. Walsh, J. A. Becker, M. J. Italia, K. A. Ingraham, M. N. Gwynn, T. Mathie, J. A. Poupard, L. A. Miller, J. R. Brown, and H. Amrine-Madsen. 2005. Molecular evolution perspectives on intraspecific lateral DNA transfer of topoisomerase and gyrase loci in Streptococcus pneumoniae, with implications for fluoroquinolone resistance development and spread. Antimicrob. Agents Chemother. 49:4315-4326.
37. Verhelst, R., T. Kayalainen, T. De Baere, G. Verschraegen, G. Claeys, L. Van Simaey, C. De Ganck, and M. Vaneechoutte. 2003. Comparison of five genotypic techniques for identification of optochin-resistant pneumococcus-like isolates. J. Clin. Microbiol. 41:3521-3525.
38. Wester, C. W., D. Ariga, C. Nathan, T. W. Rice, J. Pukirenti, R. Patel, F. Kocka, J. Ortiz, and R. A. Weinstein. 2002. Possible overestimation of penicillin resistant Streptococcus pneumoniae colonization rates due to misidentification of oropharyngeal streptococci. Diagn. Microbiol. Infect. Dis. 42:263-268.
39. Whatmore, A. M., A. Efstratiou, A. P. Pickerill, K. Broughton, G. Woodard, D. Sturgeon, R. George, and C. G. Dowson. 2000. Genetic relationships between clinical isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: characterization of "atypical" pneumococci and organisms allied to S. mitis harboring S. pneumoniae virulence factor-encoding genes. Infect. Immun. 68:1374-1382.