Molecular evolution perspectives on intraspecific lateral DNA transfer of topoisomerase and gyrase loci in Streptococcus pneumoniae, with implications for fluoroquinolone resistance development and spread

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 10, 2005, Pages 4315-4326

  Stanhope, Michael J ^a,b   Walsh, Stacey L ^a   Becker, Julie A ^a   Italia, Michael J ^a   Ingraham, Karen A ^a   Gwynn, Michael N ^a   Mathie, Tom ^a   Poupard, James A ^a   Miller, Linda A ^a   Brown, James R ^a   Amrine Madsen, Heather ^a  

^a GLAXOSMITHKLINE   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); GATIFLOXACIN; GEMIFLOXACIN; GREPAFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TROVAFLOXACIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; CONTROLLED STUDY; DNA SEQUENCE; DNA TRANSFER; GENE SEQUENCE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARC GENE; PARE GENE; PARSIMONY ANALYSIS; POPULATION DENSITY; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; UNINDEXED SEQUENCE;

AMINO ACID SEQUENCE; ANTI-INFECTIVE AGENTS; BASE SEQUENCE; DNA GYRASE; DNA TOPOISOMERASES, TYPE II, BACTERIAL; DRUG RESISTANCE, BACTERIAL; EVOLUTION, MOLECULAR; FLUOROQUINOLONES; GENE TRANSFER, HORIZONTAL; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOCOCCUS PNEUMONIAE;

EID: 25844497084     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.10.4315-4326.2005     Document Type: Article

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