The solubilisation pattern of lutein, zeaxanthin, canthaxanthin and β-carotene differ characteristically in liposomes, liver microsomes and retinal epithelial cells

Biophysical Chemistry

Volumn 129, Issue 2-3, 2007, Pages 111-119

  Shafaa, Medhat Wahba Ismail ^a,b   Diehl, Horst A ^a   Socaciu, Carmen ^c  

^a UNIVERSITY OF BREMEN   (Germany)

^b RESEARCH INSTITUTE OF OPHTHALMOLOGY   (Egypt)

^c UNIVERSITY OF AGRICULTURAL SCIENCES AND VETERINARY MEDICINE   (Romania)

Author keywords

Canthaxanthin ; EYPC liposomes; Liver microsomes; Lutein ; RPE cells; Zeaxanthin ; carotene incorporation

Indexed keywords

BETA CAROTENE; CANTHAXANTHIN; CAROTENOID; LAURDAN; LIPOSOME; TETRAHYDROFURAN; XANTHOPHYLL; ZEAXANTHIN;

ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; LIVER MICROSOME; MEMBRANE; NONHUMAN; PHOTOCHEMICAL QUENCHING; PIGMENT CELL; PRIORITY JOURNAL; PROTEIN BINDING; SERUM; SOLUBILITY; ULTRAVIOLET RADIATION;

EID: 34547588529     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2007.05.007     Document Type: Article

References (30)

1. Britton G., Liannen-Jensen S., and Pfander H. Carotenoids. Isolation and Analysis vol. 1 (1995), Birkhauser Verlag, Basel 103-107
2. Britton G., Liaaen-Jensen S., and Pfander H. Carotenoids Handbook (2004), Birkhauser Verlag AG, Basel
3. Von Luntig J., and Vogt K. Filling the gap in Vitamin A Research. Molecular identification of an enzyme-cleaving β-carotene to retinal. J. Biol. Chem. 275 (2000) 11915-11920
4. Landrum J.T., and Bone R.A. Lutein, zeaxanthin, and the macular pigment. Arch. Biochem. Biophys. 385 (2001) 28-40
5. Socaciu C., Haertel S., and Diehl H.A. Carotenoids in DPPC vesicles: membrane dynamics. Spectrochim. Acta, Part A 55 (1999) 2289-2297
6. Pintea A., Diehl H.A., Momeu C., Aberle L., and Socaciu C. Incorporation of carotenoid esters into liposomes. Biophys. Chemist. 118 (2005) 7-14
7. Socaciu C., Jessel R., and Diehl H.A. Carotenoid incorporation into microsomes: yields, stability and membrane dynamics. Spectrochim. Acta, Part A: Mol. Biomol. Spectrosc. 56 (2000) 2799-2809
8. Schalch W. Carotenoids in the retina - a review of their possible role in preventing or limiting damage caused by light and oxygen. In: Emerit I., and Chance B. (Eds). Free Radicals and Aging (1992), Birkhäuser-Verlag Base 280-298
9. Ham W.T., and Mueller W.A. The photopathology and nature of the blue-light and near-UV retinal lesion produced by lasers and other optical sources. In: Wolbarsht M.L. (Ed). Laser Applications in Medicine and Biology (1989), Plenum Press, N.Y. 191-246
10. Burton G.W. Antioxidant action of carotenoids. J. Nutr. 119 (1989) 109-111
11. Mortensen A., Skibsted L.H., and Truscott T.G. The interaction of dietary carotenoids with radical species. Arch. Biochem. Biophys. 385 (2001) 13-19
12. McCarty C., and Taylor H.R. Light and risk for age-related eye diseases. In: Taylor A. (Ed). Nutritional and Environmental Influences on the Eye (1999), CRC Press, Boca Raton 215-250
13. Schalch W. Possible contribution of lutein and zeaxanthin, carotenoids of the macula lutea, to reducing the risk of age macular degeneration: a review. HKJ Ophthalmol. 4 (2000) 31-42
14. Khachik F., Spangler C.J., and Smith J.C. Identification quantification, and relative concentrations of carotenoids and their metabolites in human milk and serum. Anal. Chem. 69 (1997) 1873-1881
15. Krinsky N.I., Russett M.D., Handelman G.J., and Snodderly D.M. Structural and geometrical isomers of carotenoids in human plasma. J. Nutr. 120 (1990) 1654-1661
16. Yemelyanov A.Y., Katz N.B., and Bernstein P.S. Ligand-binding characterization of xanthophyll carotenoids to solubilized membrane proteins derived from the human retina. Exp. Eye Res. 72 (2001) 381-392
17. Billsten H.H., Bhosale P., Yemelyanov A., Bernstein P.S., and Polívka T. Photophysical properties of xanthophylls in carotenoproteins from human retina. Photochem. Photobiol. 78 (2003) 138-145
18. Bhosale P., Larson A.J., Frederick J.M., Southwick K., Thulin C.D., and Bernstein P.S. Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye. J. Biol. Chem. 279 (2004) 49447-49454
19. Bernstein P.S., Balashov N.A., Tsong E.D., and Rando R.R. Retinal tubulin binds macular carotenoids. Invest. Ophthalmol. Vis. Sci. 38 (1997) 167-175
20. Deamer D.W., and Uster P.S. Preparation of liposomes. In: Ostro M.J. (Ed). Liposomes (1983), Marcel Dekker, New York 1
21. Steward J.C.M. Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal. Biochem. 104 (1980) 10-14
22. Lu A.Y.H., and Levin W. Partial purification of cytochrome P-450 and P-448 from rat liver microsomes. Biochem. Biophys. Res. Commun. 46 (1972) 1334-1339
23. Peterson G.L. A simplification of the protein assay method of Lowry et al., which is more generally applicable. Anal. Biochem. 83 (1977) 346-356
24. Davis A.A., Bernstein P.S., Bok D., Turner J., Nachtigal M., and Hunt R.C. A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture. Invest. Ophthalmol. Vis. Sci. 36 (1995) 955-964
25. Cooney R.V., Kappock T.J., Pung A., and Bertram J.S. Solubilisation, cellular uptake, and activity of β-carotene and other carotenoids as inhibitors of neoplastic transformations in cultured cells. Methods Enzymol. 214 (1993) 55-68
26. Parasassi T., De Stasio G., Ravagnan G., Rusch R.M., and Gratton E. Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence. Biophys. J. 60 (1991) 179-189
27. Sujak A., Gabrielska J., Grudzinski W., Borc R., Mazurek P., and Gruszecki W.I. Lutein and zeaxanthin as protectors of lipid membranes against oxidative damage: the structural aspects. Arch. Biochem. Biophys. 371 (1999) 301-307
28. Gruszecki W.I. Carotenoid orientation: role in membrane stabilization. In: Krinsky N.I., Mayne S.T., and Sies H. (Eds). Carotenoids in Health and Disease (2004), Marcel Dekker AG, Basel 151-163
29. Socaciu C., Bojarski P., Aberle L., and Diehl H.A. Different ways to insert carotenoids into liposomes affect structure and dynamics of the bilayer differently. Biophys. Chem. 99 (2002) 1-15
30. Gabrielska J., and Gruszecki W.I. Zeaxanthin (dihydroxy-beta-carotene) but not beta-carotene rigidifies lipid membranes: a 1H-NMR study of carotenoid-egg phosphatidylcholine liposomes. Biochim. Biophys. Acta 1285 (1996) 167-174