Retinal tubulin binds macular carotenoids

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 1, 1997, Pages 167-175

  Bernstein, Paul S ^a,b   Balashov, Nikita A ^a   Tsong, Edward D ^b   Rando, Robert R ^b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

binding protein; carotenoid; labeling; macula; photoaffinity; tubulin

Indexed keywords

BINDING PROTEIN; CAROTENOID; TUBULIN; XANTHOPHYLL; ZEAXANTHIN;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CATTLE; GEL FILTRATION CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; ION EXCHANGE CHROMATOGRAPHY; NONHUMAN; PHOTOAFFINITY LABELING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; PROTEIN STABILITY; RETINA FOVEA; RETINA MACULA DEGENERATION; RETINA MACULA LUTEA;

AFFINITY LABELS; ANIMALS; BETA CAROTENE; BLOTTING, WESTERN; CATTLE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; LUTEIN; MACULA LUTEA; PROTEIN BINDING; RETINA; TUBULIN; XANTHOPHYLLS;

EID: 0031015866     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Snodderly DM, Brown PK, Delori FC, Auran JD. The macular pigment: I: Absorbance spectra, localization, and discrimination from other yellow pigments in primate retinas. Invest Ophthalmol Vis Sci 1984;25:660-673.
2. Snodderly DM, Auran JD, Delori FC. The macular pigment: II: Spatial distribution in primate retinas. Invest Ophthalmol Vis Sci 1984;25:674-685.
3. Bone RA, Landrum JT, Tarsis SL. Preliminary identification of the human macular pigment. Vision Res 1985;25:1531-1535.
4. Handelman GJ, Snodderly DM, Adler AJ, Russen MD, Dratz EA. Measurement of carotenoids in human and monkey retinas. Methods Enzymol 1992;213:220-230.
5. Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E and advanced agerelated macular degeneration: A multicentcr study. JAMA 1994;272:1413-1420.
6. Schalen W. Carotenoids in the retina: A review of their possible role in preventing or limiting damage caused by light or oxygen. In: Emerit I, Chance B, eds. Free Radicals and Aging. Basel, Switzerland: Birkhauser Verlag; 1992:280-298.
7. Bone RA, Landrum JT, Hime GW, Cains A, Zamor J. Stereochemistry of the macular carotenoids. Invest Ophthalmol Vis Sci 1993;34:2033-2040.
8. Malinow MR, Feeney-Burns L, Peterson LH, Klein ML, Neuringer M. Diet related macular abnormalities in monkeys. Invest Ophthalmol Vis Sci 1980;19:857-863.
9. O'Fallon JV, Chew BP. The subcellular distribution of β-carotene in bovine corpus luteum. Proc Soc Exp Biol Med 1984;177:406-411.
10. Rodgers RJ, Lavranos TC, Rodgers HF, Young FM, Vella CA. The physiology of the ovary: Maturation of ovarian granulosa cells and a novel role for antioxidants in the corpus luteum. J Steroid Biochem Mol Biol 1995;52:241-246.
11. 2 subunit of the carotenoid pigment complex, crustacyanin. Eur J Biochem 1991;197:407-414.
12. Zagalsky PF. Carotenoproteins. In: Britton G, Liaaen-Jensen S, Pfander H, eds. Carotenoids: Isolation and analysis. Vol. 1A. Basel, Switzerland: Birkhauser-Verlag; 1995:287-294.
13. Gomez R, Milicua JCG. Use of borohydride reduction methods to probe carotenoid-protein binding. Methods Enzymol 1993;213:100-110.
14. Reddy KJ, Bullerjahn GS, Sherman LA. Characteristics of membrane-associated carotenoid-binding proteins in cyanobacteria and prochlorophytes. Methods Enzymol 1993;214:390-401.
15. Verma SP, Philippot JR, Bonnet B, Sainte-Marie J, Moschetto Y, Wallach DFH. Resonance Raman spectra of beta-carotene in native and modified low-density lipoprotein. Biochem Biophys Res Comm 1984;122:867-875.
16. Pettersson T, Ernstrom U, Griffiths W, Sjovall J, Bergman T, Jornvall H. Lutein associated with a transthyretin indicates carotenoid derivation and novel multiplicity of transthyretin ligands. FEBS Letts 1995;365:23-26.
17. Dufour E, Haertle T. Binding of retinoids and β-carotene to β-lactoglobulin: Influence of protein modifications. Biochim Biophys Acta 1991;1079:316-320.
18. Hemmi H, Hata M, Takeuchi M. Studies on the carotenoids in the muscle of salmon: V: Combination of astaxanthin and canthaxanthin with bovine serum albumin and egg albumin. Comp Biochem Physiol 1991;99B:609-612.
19. Lakshman MR, Okoh C. Carotenoid-protein complexes. Methods Enzymol 1993;214:74-86.
20. Arden GB, Barker FM. Canthaxanthin and the eye: A critical ocular toxicological assessment. J Toxicol-Cutaneous and Ocular Toxicol 1991;10:115-155.
21. Bowmaker JK, Kovach JK, Whitmore AV, Loew ER. Visual pigments and oil droplets in genetically manipulated and carotenoid deprived quail: A microspectrophotometric study. Vision Res 1993;33:571-578.
22. Bernstein PS, Choi S-Y, Ho Y-C, Rando RR. Photoaffinity labeling of retinoic acid-binding proteins. Proc Nat Acad Sci USA 1995;92:654-658.
23. Khachik F, Beecher GR, Goli MB, Lusby WR, Daitch CE. Separation and quantification of carotenoids in human plasma. Methods Enzymol 1992;213:205-219.
24. Bone RA, Landrum JT, Cains A. Optical density spectra of the macular pigment in vivo and in vitro. Vision Res 1992;32:105-110.
25. Eye Disease Case-Control Study Group. Antioxidant status and neovascular age related macular degeneration. Arch Ophthalmol 1993;111:104-109.
26. Nagle BW, Okamoto C, Taggert B, Burnside B. The teleost cone cytoskeleton: Localization of actin, microtubules, and intermediate filaments. Invest Ophthalmol Vis Sci 1986;27:689-701.
27. Taylor JD. Does the introduction of a new player, the endoplasmic reticulum, create more or less confusion in understanding the mechanism (s) of pigmentary organelle translocations? Pigment Cell Res 1992;5:49-57.
28. Handelman GJ, Snodderly DM, Krinsky NI, Russett MD, Adler AJ. Biological control of primate macular pigment: Biochemical and densitometric studies. Invest Ophthalmol Vis Sci 1991;32:257-267.
29. Bone RA. The role of the macular pigment in the detection of polarized light. Vision Res 1980;20:213-220.
30. Bone RA, Landrum JT. Macular pigment in Henle fiber membranes: A model for Haidinger's brushes. Vision Res 1984;24:103-108.