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Volumn 17, Issue 17, 2007, Pages 4829-4831
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Functionalization of the 6,14-bridge of the orvinols. Part 3: Preparation and pharmacological evaluation of 18- and 19-hydroxyl substituted orvinols
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Author keywords
Analgesics; Drug abuse; Partial agonism
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Indexed keywords
ALCOHOL;
BUPRENORPHINE;
ETORPHINE;
OPIATE DERIVATIVE;
ORVINOL;
THIENORPHINE;
UMB 94;
UMB 95;
UMB 96;
UMB 97;
UNCLASSIFIED DRUG;
ARTICLE;
BINDING AFFINITY;
CELL MEMBRANE;
CRYSTALLOGRAPHY;
DEMETHYLATION;
DRUG BINDING;
DRUG EFFICACY;
DRUG RECEPTOR BINDING;
HYDROBORATION;
HYDROXYLATION;
NONHUMAN;
OPIATE ADDICTION;
PROTON NUCLEAR MAGNETIC RESONANCE;
SUBSTITUTION REACTION;
ALCOHOLS;
ANALGESICS, OPIOID;
BUPRENORPHINE;
CHEMISTRY, PHARMACEUTICAL;
CRYSTALLOGRAPHY, X-RAY;
DRUG DESIGN;
DRUG EVALUATION, PRECLINICAL;
GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE);
MODELS, CHEMICAL;
PROTEIN BINDING;
RECEPTORS, OPIOID, MU;
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EID: 34547498743
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmcl.2007.06.050 Document Type: Article |
Times cited : (5)
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References (13)
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