Structural determinants of opioid activity in the orvinols and related structures: Ethers of orvinol and isoorvinol

Journal of Medicinal Chemistry

Volumn 43, Issue 9, 2000, Pages 1852-1857

  Coop, Andrew ^a   Norton, Claire L ^a   Berzetei Gurske, Ilona ^b   Burnside, Jackie ^b   Toll, Lawrence ^b   Husbands, Stephen M ^a   Lewis, John W ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SRI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHER DERIVATIVE; ETORPHINE; ISOORVINOL; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; OPIATE DERIVATIVE; ORVINOL; UNCLASSIFIED DRUG;

ARTICLE; CHO CELL; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; LIPOPHILICITY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

ANALGESICS, OPIOID; ANIMALS; BINDING, COMPETITIVE; CELL MEMBRANE; CHO CELLS; CRICETINAE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUINEA PIGS; HUMANS; HYDROXAMIC ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; NARCOTICS; SPECTROPHOTOMETRY, INFRARED; STEREOISOMERISM;

EID: 0034103808     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990951r     Document Type: Article

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